📌Mask?
📌If so, what type of mask?
📌How much ventilation?
📌How many people?
📌Speaking time?
📌Speaking volume?
📌Size of room?
📌Ceiling height?
📌Duration in room? #COVID19 zeit.de/wissen/gesundh…
2) VENTILATION is key. Both ventilation and masks needed to reduce risk indoors. But most buildings not ventilated well enough.
📍REALITY—Many individuals who contracted #COVID19 ~5 days before Thanksgiving are just now becoming contagious. Even if tested on Mon-Wed—tests would have been performed too soon—negative, but not actually negative. 🧵
2) “That means that even many people who tried to do the right thing and get tested before traveling, might still be delivering contagious virus to their loved ones today. If a test were taken today, many would be starting to shed enough virus to mount a positive test.
3) Unfortunately, at-home tests of contagiousness have not yet become common and turnaround times for standard tests are slow. @jeremyfaust
More than 100 doctors, physician assistants & nurse practitioners who work at urgent-care facilities within Seattle’s MultiCare health system went on strike Monday, as #COVID19 pandemic worsens, to protest working without adequate PPEs and other harsh conditions. 🧵
2) “our biggest concern and challenge is having adequate PPE [personal protective equipment] at work and feeling like we’re in as safe a work environment as possible. Our concerns are being ignored and dismissed.”
3) “The providers want access to N95 respirators, plexiglass barriers in the reception areas, and for the company to discourage patients from using waiting rooms. Also health providers don’t have time for scheduled breaks, and often work days that stretch longer than 12 hours.”
Dosing error led to Oxford AZ vaccine 90% efficacy: “error in the dosage was made by a contractor—once discovered, regulators were immediately notified & signed off on the plan to continue testing in different doses.”
2) Having done trial epidemiology, it really depends how they analyzed the data after the 2-dosing regimens. Presumably the 90% from comparing the same sample who were randomized either to the low dose & the placebo of the low dose. If same 🍎 to placebo of 🍎 group, then valid.
3) However, if they analyzed all the placebo participants as a common pool used for comparison vs both the vaccine doses, then it might be biased. But anyone with good clinical trial epidemiology training would know not to do that. But only the full report would tell us.
NEW—Trial of Hydroxychloroquine post-exposure in Spain for prevent onset of #COVID19: results found a big fat null. Nothing. Zip. Zilch. Again. Checked many subgroups too.
We have wasted so much energy and time goose chasing this. But important to debunk. nejm.org/doi/full/10.10…
2) I’ve spent what feels like eternity now debunking HCQ. So here it is hopefully for the last time... thread 🧵 on all almost trial studies HCQ.
2) we honestly shouldn’t hold any Thanksgiving gatherings. But if you must, or already committed (never too late to cancel), make sure you ventilate your home sufficiently—but this is not zero risk. The better option is outdoor gathering only.
3) Personally, I’m not gathering for thanksgiving. But if I were to, I would only do it outdoors. That is the safest honestly. Wear jackets and use heat lamps.