@WHO is concerned that there is a growing perception that the pandemic is over”, says @drtedros at #covid19 presser. "The truth is that at present, many places are witnessing very high transmission of the virus."
@WHO @DrTedros "We know it has been a hard year and people are tired, but in hospitals that are running at or over capacity it's the hardest it can possibly be”, says @DrTedros. "Please be careful. Think of health workers and act for the greater good, because it will save lives and livelihoods"
@WHO @DrTedros "The pandemic still has a long way to run and decisions made by leaders and citizens in the coming days will determine, both the course of the virus in the short term and when this pandemic will ultimately end”, says @drtedros. "Fighting this pandemic is everybody's business."
@WHO @DrTedros "With vaccines now being introduced, it’s really important that they are distributed equitably around the world”, says @drtedros. COVAX Facility, which aims to do this, is backed by 189 countries, he says.
@WHO @DrTedros “We’re asking all countries to do a country readiness assessment that takes into account cold chain, health worker capacity, micro-planning, initial target populations and training”, says @drtedros. "This will form the basis of national deployment and vaccination plans."
@WHO @DrTedros COVAX has secured 700 million doses of three vaccines, says @drtedros. “Next year we aim to use additional funds to ensure that at least two billion doses of safe and effective vaccines are available around the world."
@WHO @DrTedros The @ACTAccelerator "urgently requires a cash injection of $4.3 billion to fast-track critical areas of work and ensure that rapid tests, treatments and new #covid19 vaccines are distributed equitably”, says @drtedros.
@WHO @DrTedros @ACTAccelerator WHO’s Technical Advisory Group on Behavioural Insights and Sciences for Health, chaired by @CassSunstein, just released a report on “behavioural considerations for acceptance and uptake of #covid19 vaccines”

It’s up here: apps.who.int/iris/handle/10…
@WHO @DrTedros @ACTAccelerator @CassSunstein “This is an unprecedented and in some ways unique challenge”, says @CassSunstein. “There is a great need to adapt quickly to challenges and the technical advisory group together with @WHO colleagues will be engaged in doing exactly that.”
@WHO @DrTedros @ACTAccelerator @CassSunstein Three things should be helpful in providing a framework, says @CassSunstein:
1. "enabling environment for vaccination” is important
Where are vaccination opportunities located? How long does it take? How expensive? Are people treated with respect and kindness?
@WHO @DrTedros @ACTAccelerator @CassSunstein 2. promote favorable social norms
“Health professionals are often trusted, especially if they themselves have been vaccinated”, says @CassSunstein, especially health professionals who are part of the local community, connected to the people and place.
@WHO @DrTedros @ACTAccelerator @CassSunstein 3. "It's very important to put a spotlight on people's motivations”, says @CassSunstein. “Motivations are an outgrowth of values. They're outgrowth of emotions and they are an outgrowth of information"
@WHO @DrTedros @ACTAccelerator @CassSunstein “A central way to increase motivation is to increase trust through transparency and empathy and clarity and through meeting people where they are and listening very carefully to people's concerns and and fears”, says @CassSunstein.
@WHO @DrTedros @ACTAccelerator @CassSunstein Social benefits of getting vaccinated can also be very persuasive not just the benefit for the person getting vaccinated, says @CassSunstein. “The life you save may be your father's or your closest friend's grandmother."
@WHO @DrTedros @ACTAccelerator @CassSunstein “Vaccines do not equal zero #covid19. Vaccines and vaccination will add a major, powerful tool to the toolkit that we have”, says @DrMikeRyan. By themselves they will not do the job and therefore we have to add vaccines into an existing public health strategy."
@WHO @DrTedros @ACTAccelerator @CassSunstein @DrMikeRyan We're at an inflection point in the pandemic, says @DrMikeRyan. “We're not at a point where we can walk away from what we've been doing already. We ask that people sustain the effort sustain their behaviors, work in communities to drive community behavior."
@WHO @DrTedros @ACTAccelerator @CassSunstein @DrMikeRyan "I think the next six months are going to be difficult, but hopeful”, says @mvankerkhove. “We need to have the patience. We need to put in the work to keep ourselves safe and to keep our loved ones safe."
@WHO @DrTedros @ACTAccelerator @CassSunstein @DrMikeRyan @mvankerkhove “The decisions we make right now can change the course of the next six months”, says @mvankerkhove. "The steps that we take now mean life or death for us and mean life or death for our families."
@WHO @DrTedros @ACTAccelerator @CassSunstein @DrMikeRyan @mvankerkhove “As we enter into this critical holiday period right now, really consider what you do over this period, and who you interact with”, says @mvankerkhove. “If you can modify your contact patterns, you can modify the virus's ability to spread."
@WHO @DrTedros @ACTAccelerator @CassSunstein @DrMikeRyan @mvankerkhove Vaccines should give us hope, says @DrMikeRyan. “But those countries currently in the fight of their lives: You have got to stick with this! You've got to try and control this transmission or your health systems will not be able to cope."
@WHO @DrTedros @ACTAccelerator @CassSunstein @DrMikeRyan @mvankerkhove “We need the hope”, says @DrMikeRyan. “But we also need to be realistic. ... There are some countries on this planet whose health systems are at a point of collapse. Right now we have got to take the heat out of this transmission in order that those health systems can cope"

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More from @kakape

5 Dec
One year ago today - before the rest of the world got to experience lockdown - the islands of Samoa locked down to defeat a different virus: measles


For those who speak German: We talk about this in a new @pandemiapodcast episode
For everyone: a thread
viertausendhertz.de/pan15/
@pandemiapodcast The outbreak in Samoa started in October 2019. As usual there are multiple, complex reasons that all led to vaccine coverage declining. There was complacency, there were structural changes in the health care system, there were anti-vaccine groups. And there was a terrible tragedy
@pandemiapodcast In July 2018, two children died just after receiving the measles vaccine. Nurses preparing the vaccine had accidentally mixed the powder with an anaesthetic instead of water. (They were sentenced to 5 years in prison.)
The deaths further fuelled fears about vaccines.
Read 22 tweets
1 Dec
I don’t really remember how we marked the beginning of a new week in pre-pandemic times, but these days we celebrate “good news on vaccines” Mondays, followed by “not so good news on global #covid19" Tuesdays.
That’s to say: the WHO’s weekly sitrep is up. Quick thread
Big picture:

3,935,330 new cases and
69,916 new deaths
were reported to @WHO last week.
That means deaths have risen for a sixth week (+3%), but cases are down 4% from last week.

It is a huge amount of death and disease from one little pathogen.
@WHO Number of new #covid19 cases finally going down after two months of increases may sound great.
The problem is that the data includes the craziness of US Thanksgiving numbers.
US case number is basically the same as last week, when it should probably be a lot higher.
Read 7 tweets
1 Dec
Here we go. Moderna and Biontech/Pfizer have today submitted the data on their #covid19 vaccines to the EMA to request a conditional market authorisation. EMA spokesperson told me they think a decision could come “by the end of this year at the earliest”.
If data submitted on Biontech vaccine is robust enough, “EMA’s scientific committee for human medicines (CHMP) will conclude its assessment during an extraordinary meeting scheduled for 29 December at the latest”

ema.europa.eu/en/news/ema-re…
If data on Moderna vaccine is robust “EMA’s scientific committee for human medicines (CHMP) will conclude its assessment during an extraordinary meeting scheduled for 12 January at the latest”.

ema.europa.eu/en/news/ema-re…
Read 4 tweets
30 Nov
“Last week saw the first decline in newly-reported #covid19 cases globally since September, due to a decrease in cases in Europe”, says @DrTedros at @WHO presser. Says it’s "thanks to the effectiveness of difficult but necessary measures put in place in recent weeks”.
@DrTedros @WHO #covid19 cases are still increasing inmost other regions, says @drtedros and warns that gains can easily be lost, especially with the holiday season coming up. "This is no time for complacency."
@DrTedros @WHO "We all need to consider whose life we might be gambling with in the decisions we make”, says @DrTedros. “We all want to be together with the people we love during festive periods. But being with family and friends is not worth putting them or yourself at risk."
Read 22 tweets
30 Nov
More stunning data out from Moderna’s vaccine trial today:

Of 196 #covid19 cases
185 were in placebo group
11 in vaccine group
- 94,1% efficacy

All 30 severe #covid19 cases were in placebo group
- so that’s, well, 100% for now

There was one #covid19 death in the placebo group
“Efficacy was consistent across age, race and ethnicity, and gender demographics”


The 196 #covid19 cases included:
33 in people 65+
42 in people "identifying as being from diverse communities”
Moderna says it will submit today for EUA at FDA and for conditional marketing authorisation at EMA.

FDA meeting to review safety and efficacy data likely on December 17.

Press release here (and yes, it’s another “vaccine news by press release Monday”):
investors.modernatx.com/news-releases/…
Read 8 tweets
29 Nov
Interesting piece by @mattapuzzo and others at @nytimes looking at the list of seven demands Trump conveyed to @WHO before he announced withdrawal. No clear strategy apparent. “It was all about my country, my politics, my election”, says @LawrenceGostin. nytimes.com/2020/11/27/wor…
“The third item asked Dr. Tedros to say that countries were right to consider travel restrictions during the pandemic ... Dr. Tedros was wary of being drawn into the American presidential campaign, where travel restrictions were a rallying cry for the Trump campaign.”
“The American requests also called for the W.H.O. to pre-qualify coronavirus drugs and vaccines for use around the world once they were authorized by major regulators in the United States, Canada, Europe or Japan.”
Read 4 tweets

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