Had a phone call today to go and receive the Biontech/Pfizer vaccine at a GP Hub which had run out of patients to inoculate
We turned up at 30min notice were screened, ID checked, and vaccinated in 10min
THANK YOU to all those who contributed to this!
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It made me reflect on what a vindication COVID has been for science
The scientific method of observation, generating a hypothesis, testing the hypothesis and adapting has worked brilliantly, even if we are all pretty gloomy
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This would all have been impossible even a few years ago
The advances in molecular biology and DNA sequencing have been staggering…
And compare this to flu 1918, or the hundreds of years of Plague!
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We have gone from a novel virus to starting mass vaccination in under a year…! Do people really realise how amazing that is?
Science has learned rapidly and collaboratively, and so fast!
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We have achieved in weeks what would have taken years or decades in the past… identifying the new variant is a real achievement and hugely important - we have been able to respond… and save many thousands of lives
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And when the next pandemic arrives we can choose to be well prepared, ready to track and trace, with good ICU and hospital capacity to buy us all time, and to make a vaccine…
It’s our choice.
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I am a senior doctor in Critical Care in one of the UK’s largest Trusts, so unhappily I have gained expertise in COVID, and humbly I say that there is much more pressure on hospitals, especially their ICUs
I realise my reply may seem facetious, so I will give more details. Initially COVID was presented as a simple disease and a bit of ventilation was all that was required. In fact it isn’t.
COVID is a multisystem disease that causes pneumonia skewed towards the highest severity of illness with terrible lung disease, kidney failure, brain involvement and very abnormal blood clotting. Some patients get poor cardiac function too. Treatment is rapidly evolving.
Reckless with Hydroxychloroquine, there is a better chance Trump will be right that REGN-CoV2 will be of benefit. But we don’t know for sure and RCTs are essential
Not so sure millions of doses will be available that fast though…
And there is some observational evidence in #COVID19 for convalescent plasma, the active ingredient of which is mixed antibody
Really important paper. It proves that live virus can be cultured from air 2-5m from patients, and gets suspended in the air. This doesn’t mean social distancing is valueless, but it means it is not enough.
There are major implications for businesses returning to work in September:
1. Social distancing won’t be enough 2. Cloth masks won’t be enough - these particles are <1micron in diameter 3. Keeping the windows open is a good idea
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4. We will need to review standards for ventilation and air conditioning 5. Risks will depend on the prevalence of SARS-CoV2, footfall, and immunity… 6. Probably respires particles like these are the most dangerous because they get right into the alveoli of the lungs
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They lacked capacity, and lacked the imagination to go to big molecular labs for help, or to take on staff for proper contact tracing. Their plan was superficial and not calibrated for a more major or lethal pandemic.
You either need a lot of courage or you need to feel very safe to stick your head above the parapet and say something unpopular. And in a pandemic the decisions are huge.