DON’T PACIFY A BEAST THAT CANNOT BE PACIFIED. We did so so so many things wrong with #COVID19 response. We were sadly reactive when when should have been proactive. We fiddled while Rome burned. If we don’t stop virus this month—we are screwed. The epidemiology models are dark...
2) The Denmark 🇩🇰 CDC released this model yesterday. They are now so certain the new virus B117 strain will take over the country (and the world) by Feb and March that they show what currently happens will longer work unless we have epic suppression now!

endcoronavirus.org/papers/covid-s…
3) here is a more precise explanation of the graph and what it means.
4) Danish CDC: "it is crucial to turn the epidemic curve around and get the reproduction number significantly below 1 in the coming weeks, so that the infection rates are as low as possible when cluster B.1.1.7 becomes the dominant virus in mid-February."
5) because even if we hold the virus in check with a minimum R=0.96... by the time the new virus variant takes hold, it will be woefully insufficient, since the B117 strain is 40-80% more infectious (multiply current R*1.4 or *1.8). Other experts agree....
6) Notably, the virus is such a beast—suppose we have 1000 cases/day now... with an R=0.86 we could reduce it to 500/day in 2 weeks.

➡️But w/ added contagiousness of B117 variant that has ~60% higher R, in 2 weeks, we’d have 3000 new cases/day instead—3x!

HT @GosiaGasperoPhD
7) “it is our assessment that this variant of concern may over time, replace other circulating lineages, as seen in the 🇬🇧, and increasingly in Denmark”, WHO Europe @hans_kluge said. “W/ increased transmissibility, and similar disease severity, the variant does ... raise alarm."

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More from @DrEricDing

9 Jan
MOST EFFECTIVE INTERVENTIONS: What works best for reducing R(t)?

📌Limiting gatherings <10 people: 42% reduction

📌Closing schools & universities: 38% reduction—which was “remarkably robust“

➡️big paper published in @ScienceMagazine—Legit.

#COVID19 🧵
science.sciencemag.org/content/early/… Image
2) Notice how big a drop school closing offer in dropping R below 3.3 baseline. And especially when combined with other things, schools can bring it down below R<1. #COVID19

@dgurdasani1 has more children’s data - follow here. Image
3) here are the specific details of each govt intervention’s R reduction and their 95% CIs from@the study. Image
Read 7 tweets
9 Jan
BAD CORONAVIRUS VARIANT DATA—Folks, the B117 #SARSCoV2 variant from 🇬🇧 is a dangerous *hellish beast*. This new UK data shows attack rates (% exposed who get infected) of B117 vs common variants: B117 has 33-36% higher attack rate overall. It’s also maybe worse in kids.🧵#COVID19 Image
2) While the B117 variant is has 33-36% higher attack rate vs common types overall... it’s even greater in youngest kids. Notably, in kids 0-9, the new B117 is 43% higher in the shortcut B117 test.
assets.publishing.service.gov.uk/government/upl… Image
3) Furthermore, in genetic tests of b117, the B117 has 47.5% higher attack rate vs common virus type among kids age 0-9!

Compare that w/ only 39.5% higher for B117 among adults.

Two separate sets of data—same thing—with both pointing to higher relative increase in young kids. Image
Read 9 tweets
9 Jan
BREAKING—Reports of a highly contagious new variant in the United States are based on speculative statements made by Dr. Deborah Birx and are inaccurate, according to several government officials. CDC was dismayed and tried to stop her, but failed #COVID19
nytimes.com/2021/01/08/hea…
2) “erroneous report originated at a meeting where Dr. Birx presented graphs of the escalating cases in the country. She suggested to other members of the task force that a new, more transmissible variant originating in the U.S. might explain the surge”
3) “Her hypothesis made it into a weekly report sent to state governors. “This fall/winter surge has been at nearly twice the rate of rise of cases as the spring and summer surges...”
Read 5 tweets
8 Jan
So many GOP members of Congress laughed & mocked Rep. @LisaBRochester for her trying to hand out masks to GOP members while in lockdown during the MAGA terrorist attack on the Capitol. Such a crowded dense room—no masks. So dangerous for others. #COVID19
2) this is why I’m so worried about the riots being such a mass superspreading event.
3) We need to crush the epidemic as soon as possible. the new variant is going to rock us so bad if we don’t.
Read 8 tweets
8 Jan
ROLLOUT FINISH DATE: "All residents at elderly care homes in Denmark 🇩🇰 will have received their first dose of the #COVID19 vaccine by **today**” (if desired).

The entire country of Denmark will have gotten vaccine by June 27th. Wow!

➡️US is so behind.
thelocal.dk/20210108/today… Image
2) adults that is. Children vaccine dosing still awaiting finalization and testing.
3) Denmark is always so damn impressive. Ranking of European countries. Image
Read 4 tweets
8 Jan
Worried—Freshman GOP Kansas Congressman Jake LaTurner tests #COVID19 positive. Is 11th House member of 117th Congress—all of the same party.

But what worries me is MOCs were all holed up together yesterday during the siege. Many maskless. He was likely infectious.
2) Supposedly MOCs started getting vaccinated. But all the Freshmen MOCs yet? They just got sworn in. Also nobody has had 2nd shot yet. First shot partial protection only
3) Not just members of Congress, but also staffers and people across the US exposed to these people who are likely superspreading it as we speak as they return home.
Read 4 tweets

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