Nine vaccines have been approved so far. 53 more are in the pipeline on different stages of trials. All these vaccines cover pretty much the entire spectrum of technologies, from the ancient inactivation to state-of-the-art mRNA. 1/4
The Spike protein is highly immunogenic and many vaccines will probably work. We will have a wide choice in late 2021 / early 2022 and given the choice the interest in mRNA vaccines will most likely fade because the associated logistics are indubitably more problematic. 2/4
Pfizer and Moderna have released lots of unsupported claims lately: mRNA will stay stable at room temperature; protection will last two years; vaccines will work with variants (despite only N501Y data were released). I am grateful to those companies for their work so far. 3/4
I am very excited by the way mRNA vaccines can change medicine, not just in the field of transmissible disease. But I urge Moderna and Pfizer to adopt a more responsible communication strategy or else people will be excused from thinking they are trying the milk the 2021 cow.
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