The latest update from @ICNARC on COVID intensive care activity has been published, summarised here on behalf of @COVID19Actuary. We've now passed a sobering milestone with more admissions (12,115) in the second wave than the first (10,935), with 2,938 in the last 14 days. 1/18
Here's the recent geographical split, and the emphasis on London and surrounding regions is as clear as it is not surprising. Only the East and London have yet to pass their first wave total, and at current rates, they will do so in the next few days. This data is to 7 Jan. 2/18
The recent upsurge is very clear here, after a slight dip following the November lockdown. Whilst the early phase of the second wave was much less severe than in March, the recent increase is not dissimilar, and from a base of a much higher level of activity. 3/18
London, the East, and the SE, are now at or approaching the peak level of admissions (per head of population) as was seen in the first wave. In March the peak in London was much higher than in the rest of the population, making that particular comparison even more stark. 4/18
Here's another view that shows how London is faring worse currently. A rapid rise in cumulative admissions has quickly taken its total above the North West. The hypothesis that faring worse in the first wave would lead to a more benign second wave doesn't appear to hold. 5/18
Two views of numbers in ICU at any point in time next. The message is the same though, both in terms of the national picture and the regional split, with London fast approaching the peak situation in April, and many other areas close too. 6/18
The next few slides now have Dec data added. The total in ICU beds is well above any recent previous years, despite some saying that this is "just a normal winter". It's clearly not from this view. We are still seeing non-elective admis'ns well down though - a clear concern. 7/18
Heart attack and stroke admissions have fallen even further. It's implausible to think that these have been misclassified as COVID as the symptoms are so clear, particularly in an ICU setting. So the concern is that people are failing to present, as happened in April. 8/18
In contrast the next two could be good news. Fewer trauma admissions are likely to be related to reduced activity, particularly slips and falls by the elderly. Continuing low self-harm figures don't support the escalation of severe MH issues some have hypothesised. 9/18
Also updated for Dec, we can see COVID well in excess of normal pneumonia admissions, and are running at 12 x even the highest recent flu year. Flu has all but disappeared this year, but the offset is minimal (400 against 5,000). 10/18
Some patient characteristics next. The average age at admission is around 61. This is lower than general hospital admissions for COVID, but nevertheless 44% are under 60. The ethnic analysis shows that those of Asian ethnicity are disproportionately represented. 11/18
Those from more deprived areas are more likely to require ICU treatment, as are those with a significantly raised BMI. Note that some of these characteristics are likely to have a degree of correlation. 12/18
Only 1 in 8 of those admitted needed assistance with daily activities, and only 1 in 9 have severe comorbidities, contradicting the narrative that only those in poor health are seriously impacted by the virus. 13/18
Two graphs that indicate the stress that the NHS system is now under relate to the number of patients being transferred between hospitals. This is increasing rapidly and is now close to April levels. 14/18
Turning to outcomes, around 30% of those admitted to ICU have died, a similar proportion have been discharged from hospital, and around 40% are still in hospital, most in critical care. Another measure is survival to 28 days, which we cover next. 15/18
This measure shows a similar 28 day survival curve to the first wave, with 36% not making it through the first month. That's a sobering statistic given those entering ICU are considered to be those with the best chance of benefiting from the intensive treatment available. 16/18
A slight contrast to finish on. The first graph shows that outcomes by each age group have improved (the second wave has a slightly older age profile). But in contrast, there appears to have a deterioration since the second wave started, as volumes have increased again. 17/18
Finally, my heartfelt thanks to all of those, not only in ICU settings but across all of our health service, for your ongoing service, both to patient care and society more generally. Your commitment to your work is outstanding. Thank you! 18/18
Report: icnarc.org/Our-Audit/Audi…

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More from @john_actuary

8 Jan
The latest infection surveillance report from @ONS is out. The headline numbers are the same as in the ad-hoc update earlier this week as the data is still to Jan 2, but we now have some more detail. In England, infection levels have increased dramatically. Let's take a look.1/11
For England it's estimated that an average of 1.12m people had the infection during the week ended Jan 2nd, representing 2.1% of the community population, or 1 in 50. This rate has doubled in a month. 2/11
Regionally there are some signs that London is levelling off, but at an exceptionally high rate of 3.5%. The West Midlands, East and SE might also be levelling, but infections are still growing elsewhere. 3/11
Read 11 tweets
6 Jan
The CMI has published its Mortality Monitor for Week 52 for England and Wales. It judges the best comparison for excess deaths to be against 2019, and on this basis (chart 2), the excess has now reached 13%, all of which arose during the last 9 months. 1/4 actuaries.org.uk/system/files/f… Image
The latest week has an excess of 51%, but this is a result of the timing of the Bank Holiday this year, so is not representative of the true picture. The next two weeks (including the final week 53, and first week of 2021) are likely to be similarly distorted. 2/4
This analysis uses age-standardised mortality, which adjusts for changes in population size and age distribution, and is thus a better measure. With an ageing population it typically produces lower percentage excesses than a simple death count would.
Read 4 tweets
1 Jan
The latest @ICNARC update on ICU activity was published yesterday, and is summarised here on behalf of @COVID19actuary. Focussing on patient numbers (as outcomes are little changed), there's a clear upswing in admissions in the south east of the country, particularly London. 1/12
Five areas have now surpassed their first wave total and in total the figure is now at 93% of the first wave and will be exceeded in the next week at current rates of admission. 2/12
A visual representation of how the second wave has been more spread than the first, and also how the numbers are rising again after falling during the second half of November. The current gradient looks steeper than anything seen to date in this wave. 3/12
Read 13 tweets
31 Dec 20
The @ONS issued an ad-hoc update of infectivity levels yesterday, covering the period up to Dec 23rd. It suggests by that date, 1.7% or 932,000 were infected in England, a 38% increase in 7 days. These modelled estimates do smooth the data, but the rate of increase is clear. 1/5 Image
The regional picture will come as no surprise, with infectivity in London put at 3.5%, up 60% in a week. That's very consistent with recent admissions growth in London. As this data is a week old, today's admissions broadly equate to infections for the latest week shown. 2/5 Image
There's also data on prevalence of the new variant, now (or should I say, "then") over 70% in the wider south and east part of England, less than half of that in most other regions. 3/5 Image
Read 5 tweets
24 Nov 20
The latest data on registered deaths shows a continued increase in excess deaths, and we've now passed the grim milestone of exceeding 2019 total deaths. I've seen comment that the recent xs is due to a catch up of registrations. There's no evidence of that as we can see... 1/3
The ONS helpfully provides an estimate of weekly deaths by date of death. Recent weeks have more uncertainty, as a smaller proportion of the eventual total has been registered, but it's clear that the view is still of continuing increases. 2/3
This data is all just based on the weekly raw death numbers. As @ActuarybyDay notes, a better view, adjusting for population growth and ageing of the population will be published later today by the CMI, and we will link to it with analysis when released. 3/3
Read 4 tweets
17 Nov 20
The actuarial profession's CMI has produced its weekly update on mortality during the pandemic. It reports that in the latest week (to 6th Nov) excess deaths were 9% above expectation. Some more context to follow. 1/11
The analysis uses age standardised mortality rates, which adjusts for changes in the size/age dist'n of the pop'n. This gives a better answer than using numbers of deaths - typically you get a lower excess as our population is ageing, so we would expect more deaths each yr. 2/11
This chart compares 2020 with the average of 10-19. Note that as mortality has improved over the decade you would expect more recent years to be lower, and vice versa. Note also how close 20 was tracking to 19 before late March. You can see the line drifting up again now. 3/11
Read 11 tweets

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