1/ Why are hypodermic needles and IV catheters referenced by gauge numbers?
And why does the needle diameter get smaller as the gauge number increases?
Let's explore the obscure history of IV sizing in the following #histmed#tweetorial.
2/ The gauge numbers on modern hypodermic needles are adapted from the Birmingham Wire Gauge (BWG), a system developed during the Industrial Revolution in the early 1800s to standardize the British cottage industry of iron and steel wire manufacturing.
3/ As early as the 1200s wire was made through the process of wire-drawing, which involved pulling iron rods through a conical hole in a draw-plate or gauge.
The resultant wires could then be drawn through successively smaller diameter gauges to produce thinner wire.
4/ As iron work was a cottage industry, each manufacturer had their own draw-plates and dies which resulted in proprietary wire thicknesses.
These gauges did not represent actual measurements of the wire diameter but rather the number of draw-plates the wire would pass through.
5/ Eventually sophisticated measurement allowed for quantification of existing gauges in 1/1000s of an inch.
Since development of the gauges predated the ability measure in standard units of length, there is no logical or linear progression of measurement between gauge sizes.
6/ Interestingly, while there is no linear progression, there is an exponential decay seen within the Birmingham Wire Gauge as each successive gauge wire is ~11% thinner than the prior gauge number, likely due to the cohesive strength of the iron wire itself.
7/ As industrialization increased globally, so did demand for a standard. The British engineering industry would debate several options including switching to a millimeter-based system, like the French gauge (1Fr = 1/3mm), and inventing a new gauge based on the inch.
8/ Ultimately, Queen Victoria would keep the existing BWG as its own standard since it was Imperial, familiar, and easier to say “18 gauge” than “50 thousandths of an inch”.
The BWG was also largely adopted by the USA which soon surpassed the UK in steel manufacturing.
9/ Use of the Birmingham Wire Gauge continued into the 20th century and during World War I, the Randall-Faichney Company would become one of the largest producers of hypodermic needles, making the BWG a needle measurement standard we use today.
10/ To summarize:
💉 IV gauges are based on British wire diameters from the 1800s.
💉 ⬆️ gauge number = ⬇️ diameter needles because wire was drawn through progressively smaller dies.
💉 Unlike French gauge which ⬆️ linearly, there is no linear progression of BWG IV gauge sizes.
11/ For further reading, be sure to check out the following articles used as sources for this tweetorial.
3/ BNP is a hormone secreted in response to ventricular wall stretch. It binds to natriuretic peptide receptor A (NPR-A) which ⬆️ cGMP in various tissues to exert MANY effects including:
⬆️ Natriuresis
⬇️ RAAS
⬇️ sympathetic tone
& so much more!
1/ "Who feels comfortable evaluating a tracheostomy?"
Today on the wards we talked trachs. Though we see patients with trachs regularly I find it is a topic that few learners are comfortable with.
The following 🧵 is my "Hospitalists' Guide to Tracheostomies"
2/
Where are trachs placed anatomically?
Trachs are placed between the cricoid cartilage and the sternal notch around the 2nd to 4th tracheal ring. These can be placed surgically or percutaneously at the bedside.
3/ Anatomy of a Trach
When evaluating a trach, I find it helpful to consider the following:
🔹 Diameter - Is there an inner cannula or single lumen?
🔹 Length - Is it regular size or an Extended Length Trach (XLT)?
🔹 Cuffed or cuffless?
🔹 Fenestrations present?
I occasionally hear atelectasis listed in the differential diagnosis for early post-op fever (EPF) but this idea has never made much physiologic sense to me.
Let's explore this question in the following #tweetorial.
2/ Like many US medical students, I first learned this central dogma of post-op fever on my surgical clerkship through the perpetuation of a rather cumbersome and inelegant mnemonic involving the letter W.
3/
Despite its ubiquity, however, there is little published evidence to support this idea. One of the largest systematic reviews on the topic found that in 7 of 8 studies there was no significant association between atelectasis and early post-op fever.
1/ Why are EKG waves named starting with the letter P? What happened to letters A through O?
I’m guessing you’ve probably never wondered this, but if you’re curious, here’s a brief historical #medthread / #tweetorial on how the EKG waves got the names they did.
2/ The first electrical tracings of the heart were obtained in 1887 by A.D. Waller, a British physiologist and physician, who used a Lippmann capillary electrometer to capture the tracings.
3/ As a physiologist, Waller labelled the two waves on his initial tracing V1 & V2 based on their site of anatomic origin- the ventricle. He would continue, often rather adamantly, to refer to the electrical waves as A, V1, & V2 throughout his career.
1/ Ok #medtwitter, here goes my first attempt at a #tweetorial, inspired by a recent question on wards from a learner I didn't know the full answer to:
“How good is a tuberculosis (TB) 'rule-out'?”
To try to answer this question we'll first start with a case.
2/ A 62yo female w/ recent renal transplant and remote hx of pulm TB s/p 1y DOT presents with fever. 4 wks PTA was hospitalized for 2 wks of cough, unintentional 20lbs weight loss & large LUL cavitary lesion on CT.
3/ Extensive work-up including bronchoscopy only reveals +human metapneumovirus. 4 AFB sputum smears and 3 MTB PCRs (including BAL) are negative. AFB cultures are NGTD. Patient is d/c on empiric posaconazole. 1 wk later she returns to ED with temp 102F. Cough is now resolved.