#idboardreview 12 prisoners from Mississippi jail present with varying symptoms of acute b/l cranial neuropathies and descending weakness after drinking 'hooch'. Diagnosis? #medEd#idmedEd
honey, potatoes, apples & tomato paste from a bulging can were combined, hidden, fermented in sealed plastic bag at room temperature for 3–5 days. Possible sources of Clostridium botulinum or toxin include tomato paste, potatoes, contamination from the environment.
gram positive strictly anaerobic bacillus that forms a subterminal spore. Presumptive dx based on clinical presentation: symmetric descending paralysis, b/l CN palsies/ supportive care, antitoxin
• • •
Missing some Tweet in this thread? You can try to
force a refresh
#idboardreview 30 M from Thailand 🇹🇭 new dx HIV CD4 5 presents w/ fever, sore throat, dry cough, generalized umbilicated skin lesions x2wks. Diagnosis? #medEd#idmedEd#IDtwitter
#Talaromyces marneffei cause of morbidity and mortality in HIV-infected & other immunosuppressed patients who live in or are from endemic areas especially Southeast Asia. Amphotericin B or Itraconazole should be initiated as soon as possible for patients with talaromycosis
Mortality ranges 8-40%. Common clinical manifestations include fever, weight loss, anemia, weakness, skin lesions, lymphadenopathy and hepatosplenomegaly #talaromycosis
#IdBoardReview 65 M presents w/ severe pain in leg for few hours, progressed to rapid swelling/bullae and +gas on X-ray. hx of bright blood per rectum for few months. diagnosis? #idmedEd#medEd
#Clostridium septicum spontaneous non-traumatic gas gangrene associated with malignancy likely colorectal CA in this case
Spontaneous traumatic gas gangrene is most commonly due to Clostridium perfingens & sometimes other clostridia sp. Non-traumatic spontaneous gas gangrene: most commonly due to C septicum: 80% malignancy related, most common CA are colon f/b hematologic
#IdBoardReview 25 F recent Caribbean vacation, walked barefoot on sand and now with creepy rash. diagnosis? #idmedEd#MedEd
Cutaneous larva migrans is a characteristic serpiginous skin lesion which may be seen in travelers Carribean & Americas. most common causative organisms are Ancylostoma braziliense and Ancylostoma caninum.
#CLM most commonly transmitted by animal feces depositing eggs in soil/sand, with larvae entering humans through direct contact with skin. Cutaneous larva migrans is distinguished from cutaneous manifestation of Strongyloides stercoralis infection termed larva currens
#idboardreview 65 F no PMH p/w fever, headache x2d, winter, brought by family as not acting like herself, hyperactive, animated movements. No animals, no outdoor activities, not sexually active. Diagnosis? #medEd#IDMedEd
Herpes simplex #HSV encephalitis is most common acute sporadic focal encephalitis in USA (1-2cases/1 million persons/yr. 1º infection or by reactivation of latent virus. In case of 1º oropharyngeal disease, spread along olfactory or trigeminal nerve has been hypothesized
other neuronal pathways may be involved in reactivation of latent virus. Infection or reactivation leads to focal inflammation, often in the temporal lobe, with associated neurologic deficits.
#IdBoardReview 30 M injection drug use, hx of MRSA IE s/p tricuspid/mitral valve repair 1 year ago now presents with weakness, chills, BC+GPC w/ aerobic sticky staph-like white-gray colonies. TEE+TV vegetation. pathogen? #idmedEd#medEd
#Rothia mucilaginosa is increasingly recognized as an emerging opportunistic pathogen associated with prosthetic device infections. Gram-positive cocci, catalase negative, sticky “staph-like” colonies whitish to gray in color, nonhemolytic, smooth, and round