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Brianna Bibel Profile picture
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24 Jan, 8 tweets, 2 min read
Just in case you need some splice in your life... 1/8: gene to protein overview Image
2/8: pre-mRNA to mRNA Image
3/8: alternative splicing Image
4/8: exon shuffling Image
5/8: splicing mutations Image
6/8: splice-switching ASOs Image
7/8: translation-coupled mRNA decay Image
8/8: nonsense mediated decay (NMD) Image

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More from @biochem_bri

Brianna Bibel Profile picture
7 Jan 20
Spectroscopy allows us to spy on molecules invisible to the naked eye. Through a cuvette the spectrophotometer allows us to peer and measure concentrations with the help of Beer! 👉 bit.ly/2N4nzXE
#366DaysOfScience #biochemistry #scicomm #realtimechem
The Beer Lambert law (Beer’s law) allows you to convert between concentration (c) of a dissolved thing (solute) & absorbance of light. Don't have a lot - use a NanoDrop so the UV-Vis fun don't stop! bit.ly/beerslawexplai…
#366DaysOfScience #biochemistry #scicomm #realtimechem
Do you listen to your spectrograph peaks when they try to speak? Or just look at highest 1 & assume purification's done? Peakiest peak *might* tell concentration - but rest can reveal contamination! 👉 bit.ly/2NblGc2
#366DaysOfScience #biochemistry #scicomm #realtimechem
Read 360 tweets
Brianna Bibel Profile picture
5 Oct 18
After a jam-packed 2 days at #SciOut18🌪(thx @ASBMB & @rockedu_!) it was time to reflect! 🤔 Reflection is so important, but it can be hard to find ⏰ to really just think! 💭 Some of my thoughts 👉 instagram.com/p/BokNO_NhihF/
#365DaysOfScience #biochemistry #scicomm #sciout #science person looking thoughtful in front of mirrornotebook pagenotebook pagenotebook page
What’s inside? 🧐 It’s FORMAMIDE! 🤗 Formally removing RNA’s form with formamide! 🤓 FORMAMIDE in loading buffer breaks up & replaces the bonds between bases holding RNA's shape together 👇
instagram.com/p/BomwR32B4MX/
#365DaysOfScience #biochemistry #scicomm #lifeinthelab #science person looking through safety goggles with formamide drawn on themformamide RNA denaturant explanation
Bring on the heat! 🔥 To help denaturants get to the huddling hydrophobic bases, we add heat ♨️ 👉 gives molecules more energy so they can “pull apart” more easily ⏩ easier access 👍 More 👇
instagram.com/p/Boo2yazBDDi/
#365DaysOfScience #biochemistry #scicomm #lifeinthelab #science person putting tube in heating block
Read 308 tweets

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