"A year ago today, fewer than 1500 cases of #COVID19 had been reported to @WHO, including just 20 cases outside China”, says @DrTedros at WHO presser. "This week, we expect to reach 100 million reported cases.”
@WHO @DrTedros "Numbers can make us numb to what they represent: every death is someone’s parent, someone’s partner, someone’s child, someone’s friend”, says @drtedros. "Vaccines are giving us hope, which is why every life we lose now is even more tragic."
@WHO @DrTedros "Last week, I said that they will distribute on the brink of a catastrophic moral failure if it doesn't deliver equitable access to vaccines”, says @DrTedros. "Two new studies show that it wouldn't just be a moral failure. It would be an economic failure."
@WHO @DrTedros 1. Report from International Labour Organization found "decline in global labor income equivalent to $3.7. trillion” and recommended supporting low and middle-income countries in rolling out vaccines to help economic and employment recovery.
ilo.org/wcmsp5/groups/…
@WHO @DrTedros 2. Study commissioned by International Chamber of Commerce Research Foundation “finds that vaccine nationalism could cost the global economy, up to $9.2 trillion and almost half of that, $4.5 trillion, would be incurred in the wealthiest economies.”
iccwbo.org/media-wall/new…
@WHO @DrTedros “It is in every nation's own medium and long-term economic interests to support vaccine equity”, says @drtedros. "Until we end the pandemic everywhere, we won’t end it anywhere."
@WHO @DrTedros “As we speak, rich countries are rolling out vaccines, while the world’s least-developed countries watch and wait”, says @drtedros. "Every day that passes, the divide grows larger between the world's haves and have-nots."
@WHO @DrTedros Olympics Q: Should athletes be prioritised for vaccination?
The Games are “a wonderful symbol for our shared humanity”, says @DrMikeRyan. "However, we have to face the realities of what we face now: There is not enough vaccine right now to even serve those who are most at risk."
@WHO @DrTedros @DrMikeRyan "I don't believe we should start setting elimination or eradication of this virus as the bar for success”, says @DrMikeRyan. “The bar for success is reducing the capacity of this virus to kill, to put people in hospital, to destroy our economic and social lives."
@WHO @DrTedros @DrMikeRyan “We've only ever eradicated one disease on this planet, smallpox, and we're struggling against polio and we're struggling to eliminate measles”, says @DrMikeRyan (not counting rinderpest). "If we look to eradication as the measure of success, I think we're going to struggle."
@WHO @DrTedros @DrMikeRyan “If you're going to have a successful national vaccine action plan, you must involve the private sector”, says @ICCSecGen. “It's the genius of the innovation of the private sector, which will help on distribution, not just in developed countries but also in developing countries,"
@WHO @DrTedros @DrMikeRyan @ICCSecGen Current situation could lead to a managed trajectory of the pandemic in the North "but actually an unmanaged trajectory in the South”, says @ICCSecGen. There is "a compelling economic case, not just persuasive. to actually fully fund the COVAX facility."
@WHO @DrTedros @DrMikeRyan @ICCSecGen “The overall pattern in the Americas is beginning to stabilize”, says @DrMikeRyan. “The increases are not as as stark as they have been, but the health systems across the whole region are under pressure, and people like in the rest of the world are very very tired."
@WHO @DrTedros @DrMikeRyan @ICCSecGen Unlike Europe and other places the Americas never really had a period with low case numbers, @DrMikeRyan notes. ”The Americas and particularly Central and South America has had a punishing pandemic in terms of the persistence, and the relentless impact of the disease"
@WHO @DrTedros @DrMikeRyan @ICCSecGen “We are seeing reduced incidence in a number of countries that have different virus variants that have been identified: in South Africa, in the United Kingdom and Ireland and Denmark”, says @mvankerkhove "The control measures work."
@WHO @DrTedros @DrMikeRyan @ICCSecGen @mvankerkhove "We hope that all countries who wish to enhance their genetic sequencing capacity and contribute that data to the global knowledge will be able to do so”, says @drmikeryan. @WHO is "in a position to help connect them with the necessary technology and training to achieve that.”

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More from @kakape

27 Jan
Getting a lot of questions about vaccines and variants and why @moderna_tx is developing a booster based on variant discovered in South Africa if vaccines are thought to protect against it.
So a quick thread.
And story is up here:
sciencemag.org/news/2021/01/v…
@moderna_tx First of all, there are several ways in which new variants can worsen the situation:
They can be deadlier, more transmissible or more likely to infect people who have been infected already or received vaccines - or, of course, a combination of these.
@moderna_tx The biggest problem for the world RIGHT NOW are variants with increased transmissibility, because that means measures have to be stricter for the virus not to spread and if it does spread it means more disease and death before the world is vaccinated.
Read 15 tweets
21 Jan
New @ECDC_EU risk assessment on variants of concern says likelihood of them spreading in Europe is very high, likely leading to more transmission and death. “Stricter NPIs are needed to reduce transmission and relieve the pressure on healthcare systems.”

ecdc.europa.eu/en/publication…
Detection:
- “Member States need to increase the level of surveillance and sequencing of a representative sample of community #COVID19 cases”
- “Member States should prepare laboratories for a higher demand for testing”
Curbing transmission:
- compliance with stricter non-pharmaceutical interventions than those currently implemented, and strengthened case detection with contact tracing
- non-essential travel should be avoided
- accelerate vaccination of high-risk groups
Read 5 tweets
18 Jan
Today’s presentation from South Africa on 501Y.V2 (the second variant of concern in case you've lost count) is very interesting.

Regrettably it only adds to concerns about potential immune escape from this variant:

When convalescent sera from 44 people infected in first wave in South Africa was confronted with 501Y.V2, antibodies from 21 out of 44 did not recognize the variant.
Important to remember that our immunity is not just due to antibodies, but also T cells. So fingers crossed!
There are other caveats: Vaccine- induced immunity may be very different from natural immunity, for instance.

This is just one data point, but as so often in the last weeks I would have preferred different data 🤷‍♂️
Read 4 tweets
16 Jan
Situation with new #sarscov2 variants is becoming harder to follow (and not just because of the names), so let me try and give a brief overview: Where are we at? What should we be worried about? And how worried?

Story is up here: sciencemag.org/news/2021/01/n…
And now a thread...
For now there are three variants with sufficient evidence for scientists to be really concerned and I‘ll start with the newest one: P.1.
This was described on Tuesday from December samples from Manaus and had already been picked up in Japan in travelers.
virological.org/t/genomic-char…
Why is it concerning? Three main reasons:
1. The place: P.1 is spreading in Manaus, which is experiencing a devastating surge after already experiencing a terrible wave of infections in March/April. @DrMikeRyan described the dire situation yesterday:
Read 18 tweets
15 Jan
“Some countries in Europe, Africa and the Americas are seeing spikes in cases with multiple factors driving transmission risk”, says @drtedros at @WHO presser. “At present, there is immense pressure on hospitals and health workers."
@DrTedros @WHO “With almost 2 million deaths and new variants appearing in multiple countries, the emergency committee emphasized the need for governments to do all they can to curb infections through tried and tested public health measures”, says @DrTedros.
@DrTedros @WHO Push for equitable vaccine rollout needs to continue, says @drtedros
"I came into public health, because I wanted to ensure that everyone everywhere has access to quality health services.
I know what it's like to come from a continent where not all health services are available."
Read 20 tweets
14 Jan
Big days ahead in German politics as the Christian Democrats choose a new leader and chart a course for a post-Merkel era.
If you want to get up to speed on what's at play (and who’s playing), this piece by @SophiaBesch and @COdendahl is a great start:
cer.eu/insights/choos…
@SophiaBesch @COdendahl Unlike the Social Democrats, the CDU “has largely managed to hold together a broad coalition of voters. The key question for September is whether Merkel was the glue. 
There is good reason to believe that she was.”
@SophiaBesch @COdendahl "No successor will have Merkel’s broad appeal and be able to hold onto that support once the pandemic is over. But some have a better chance than others. “
Read 4 tweets

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