Today’s presentation from South Africa on 501Y.V2 (the second variant of concern in case you've lost count) is very interesting.
Regrettably it only adds to concerns about potential immune escape from this variant:
Regrettably it only adds to concerns about potential immune escape from this variant:
When convalescent sera from 44 people infected in first wave in South Africa was confronted with 501Y.V2, antibodies from 21 out of 44 did not recognize the variant.
Important to remember that our immunity is not just due to antibodies, but also T cells. So fingers crossed!
Important to remember that our immunity is not just due to antibodies, but also T cells. So fingers crossed!
There are other caveats: Vaccine- induced immunity may be very different from natural immunity, for instance.
This is just one data point, but as so often in the last weeks I would have preferred different data 🤷♂️
This is just one data point, but as so often in the last weeks I would have preferred different data 🤷♂️
So is immune escape contributing to the resurgence in South Africa? We don’t know yet.
As @ProfAbdoolKarim says, anecdotal reports are to be expected:
“Are we seeing a systematic increase in reinfections? Certainly the data at this point do not point in that direction.”
As @ProfAbdoolKarim says, anecdotal reports are to be expected:
“Are we seeing a systematic increase in reinfections? Certainly the data at this point do not point in that direction.”
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