As 2020 prelim. total mortality data now reasonably complete, here is an update on the age-standardised analysis for 2000-2020 for Finland Norway Sweden.

Although Sweden 2020 is of interest, a comparison between Finland/Norway is interesting too.

1/17

Starting with Fig 1, the absolute numbers of deaths per year in Sweden, Norway, Finland.

Sweden as the largest country has naturally most deaths. Year 2020 stands out.


But Finland and Norway: almost the same population size; why Norway fewer deaths + the trends diverging?

2/
Population sizes generally growing over time in the nordics. Despite this, the total number of deaths has been rather stable in Fig 1, Sweden (except 2020) and Norway actually decreased despite more people.

Note also how Finland stands out in population growth.

3/
We can express the nr of deaths per a fixed number; for example “per million”, as in Fig 2. How many would have died if the pop. was 1 million in each country? Easier to compare cntries+over time.

Need to know pop. sizes + deaths for every year. The measure is now a “rate”.

4/
A rate describes how many deaths occur per some fixed population (here million) and time unit (here per year).

This rate is also called “crude rate” in epidemiology, as it only takes into account the population sizes over years, nothing else.

5/
Measured this way, we can now compare deaths in the countries even though the population sizes differ:

- Norway has lowest rate and decreasing.
- Sweden had highest, but has decreased.
- Finland was lowest but increased and now highest.

Why these differences?

6/
Age is strongly associated with mortality so the next step is to figure out if there are any differences in how old people in different countries are.

Median ages 1990 -> 2015:
- Finland 36.4 -> 42.5
- Sweden 38.4 -> 40.9
- Norway 35.4 -> 39.2

7/

ourworldindata.org/age-structure
Norway with youngest population has lowest crude mortality rate in Fig 2, as would be expected.
Sweden used to be oldest, but ageing has been slower than in Finland/Norway.

Finland now oldest, ageing has been more rapid.

8/
Number of things affect pop. age-structure eg:
- differences/changes in public health (mortality due to disease burden, lifestyle eg smoking, etc)
- fertility (number of children per woman)
- immigration (I assume immigrants on average younger than general population).

9/
Fertility rates not favouring Finland: 1.77 vs Norway 1.82, Sweden 1.91 births/woman.

Thus, Finland not getting as many young into the population as the others.

Immigration more common in Sweden, also Norway more than twice as many foreign-borns.
(ourworldindata.org/fertility-rate)

10/
One can take into account the differences in age by calculating the rates expressed per a *common age distribution.

Need data on pop. size in all age groups and all years, as well as nr of deaths in all age groups for all the years.

11/
This corresponds to the “per million”-calculation above (sort of), "per common nr people" (to account for differences in population sizes), same principle.

Calculation is quite simple, see for example (or google “direct standardisation”):

12/

healthknowledge.org.uk/e-learning/epi…
This is called age-standardization (or age adjustment): the rates tell the mortality *as if the age-structure had been the same in different years and populations.*

Generally, the rates have been declining everywhere, Fig 3.

13/
I chose to use Swedens age distribution year 2010 as reference (choise does not matter for comparison, but affects absolute values).

Thus, rates in Fig 3 are for “one million population with age-distribution as in Sweden in 2010”, for each country.

14/
Still small difference between Norway/Finland in Fig 3, not explained by differences in age/pop. size.

Next step: check common diseases, lifestyle associated w mortality (smoking, obesity..) in the cntries. (Will not go there; it is the middle-aged finnish men with excess.)

15/
The differences seen in age-standardized rates in Fig 3 are also reflected in life-expectancy at birth (WHO 2019):

Finland: 81.6 years
Sweden 82.4
Norway: 82.6

16/
It is possible to standardise for other background factors which might differ between countries/change over time, the principle is the same.

(In fact, the “age-standardised rates” here are also standardised for diffs. in nr of men and women in different countries/years.)

17/
Summary:
- Sweden has had lowest mortality rates but this year lost this advantage.
- In comparisons to long term historical levels, one has to consider changes in population demographics.
- Comparing to historical levels, need to consider improvements in public health.

18/18

• • •

Missing some Tweet in this thread? You can try to force a refresh
 

Keep Current with Markku Peltonen

Markku Peltonen Profile picture

Stay in touch and get notified when new unrolls are available from this author!

Read all threads

This Thread may be Removed Anytime!

PDF

Twitter may remove this content at anytime! Save it as PDF for later use!

Try unrolling a thread yourself!

how to unroll video
  1. Follow @ThreadReaderApp to mention us!

  2. From a Twitter thread mention us with a keyword "unroll"
@threadreaderapp unroll

Practice here first or read more on our help page!

More from @MarkkuPeltonen

27 Jan
Covid-19 in the nordics and Estonia 27.1.

Confirmed cases: Sweden Denmark declining, Estonia stable but now highest of these. 1/4

Varmistetut tapaukset, ei erityistä uutta kommentoitavaa. Viro tasainen korkealla tasolla.
The underlying data for the previous 7-day moving average picture, to illustrate the day-to-day variation in reporting. (Sweden excluded.) 2/4

Päivittäiset määrät (per miljoona) havainnoillistamaan päivittäistä vaihtelua raportoinnissa.
Patients in hospital care, either stable or declining everywhere. Changes in Sweden seem rapid. 3/4

Sairaalahoito, tasaista tai laskua joka puolella.
Read 4 tweets
16 Sep 20
Syyskuussa twitterini täyttyy tuskailevista tutkijoista. Useiden tutkimusta rahoittavien organisaatioiden hakuaika on nyt, ja hakemukset saatava valmiiksi. Mitä tutkjat tarkalleen nyt tekevät, ja miksi?

Ehkä kiinnostavaa ei-tutkijoille. Terveystieteiden näkökulmasta. 1/
Tutkija tarvitsee rahaa omaan ja työntekijöiden palkkoihin, ja tutkimuksen käytännön tekemiseen. Sitä voi yrittää saada omasta organisaatiosta, tai hakemalla ulkoisia, kilpailtuja rahoituksia. Useilla oma palkkakaan ei siis ole varma vaan hankkittava erilaisista lähteistä. 2/
Lähteitä ovat Suomen Akatemia, yksittäiset kansalliset säätiöt, EU:n rahoitusmekanismit, Akatemiaa vastaavat ulkomaiset instanssit (Ruotsissa Vetenskapsrådet, jenkeissä NIH ym), kansainväliset säätiöt. Säätiöitä esim Diabetestutkimussäätiö ja Juho Vainion säätiö. 3/
Read 14 tweets
2 Sep 20
Tämä on tärkeä kysymys johon hankala vastata tarkasti. Käsitykseni Suomen osalta jos keväällä olisi testattu kuten nyt, ilmaantuvuusluvut silloin keväällä olisivat olleet moninkertaisia mitä nyt siis havaittiin. 1/5
Tätä tukee epäsuorasti sairaala- ja kuolleisuusluvut jotka nyt tosi alhaisia eli tautia vähän.

Näiden tulkinnassa oltava kuitenkin varovainen sillä näihin vaikuttaa myös se missä väestönosissa tauti leviää (nuoret/vanhat jne) ja 2/5
myös hoito voinut muuttua mutta ehkä tämän vaikutus kuitenkin vähäisempi?

Osa väittää että myös itse tauti voisi olla vähemmän vaarallinen nyt, mutta käsittääkseni mitään näyttöä tästä ei ole. 3/5
Read 6 tweets
12 Aug 20
Suomessa keskusteltu julkaisemattomien ns preprint-artikkeleiden arvioinnista, esimerkkinä meta-analyysi maskeista. Tässä miten arviointiprosessi lääketieteessä normaalisti ennen julkaisua menee; ehkä kiinnostavaa ei-tutkijoille/muiden tieteenalojen tutkijoille. 1/
Preprint tarkoittaa Avoimen julkaisemisen sanaston mukaan "käsikirjoitusversio, jonka kirjoittaja on lähettänyt kustantajalle ja jota ei ole vertaisarvioitu. Ei siis välttämättä sisällöltään lopullinen versio artikkelista.". (Voiko olla myös versio mitä ei vielä lähetetty?) 2/
Jutun tullessa lehteen lehden "tieteellinen toimittaja" (editor) tekee 1. arvion ja voi hylätä (reject) suoraan jos ei kiinnostava/sopiva lehteen tai huonolaatuinen. Tai kutsuu ulkoisia, riippumattomia tutkijoita, pyytää heitä arvioimaan jutun. Aikaa annetaan yleensä 1-12 vkoa.3/
Read 16 tweets
4 Aug 20
Recently there was a meta-analysis on the effects of masks conducted in Finland. A number of comments has been made about the quality of the piece, so I had a quick look at it. As the analysis was also mentioned at least in Sweden, few quick comments in English. 1/10
Background: the Finnish Ministry of Social Affairs and Health did a systematic review in May 2020 on the use of community face coverings to prevent the spread of Covid-19. There was no meta-analysis in the review, which focused on effectiveness. 2/10
The conclusion on that report was “very little research data available on the effectiveness of community face coverings in preventing the spread of COVID-19 in society.” and evidence “minor” or “non-existent”. 3/10
Read 13 tweets
26 Jul 20
When evaluating actions aiming to improve public health, results can be measured as efficacy and effectiveness. It is common to use the terms interchangeably, referring to ability to produce a desired result. In medicine and public health, however, they mean different things. 1/6
Efficacy is what can be achieved under ideal/controlled setting (eg randomised controlled trial). With strict inclusion/exclusion criteria, one can select a homogenous, motivated study population. Interventions and outcomes can be delivered and measured in a controlled way. 2/6
Effectiveness is what can be achieved when the intervention is used in real world setting. Usually, the effects are less than what the efficacy studies indicated. Potential reasons include more heterogenous and less motivated population, lack of follow-up and feedback, etc. 3/6
Read 6 tweets

Did Thread Reader help you today?

Support us! We are indie developers!


This site is made by just two indie developers on a laptop doing marketing, support and development! Read more about the story.

Become a Premium Member ($3/month or $30/year) and get exclusive features!

Become Premium

Too expensive? Make a small donation by buying us coffee ($5) or help with server cost ($10)

Donate via Paypal Become our Patreon

Thank you for your support!

Follow Us on Twitter!