Mayo Clinic staging and risk stratification systems for plasma cell disorders. @MayoClinic @MayoCancerCare @MayoMyeloma @Rfonsi1 @MorieGertz @myelomaMD
1) Mayo 2005 MGUS Risk Stratification. ashpublications.org/blood/article/…
3 risk factors:
M spike size
M spike type
FLC ratio
1) Mayo 2005 MGUS Risk Stratification. ashpublications.org/blood/article/…
3 risk factors:
M spike size
M spike type
FLC ratio
2) Mayo 2012 Staging for AL Amyloidosis:
3 risk factors:
Cardiac Troponin T >0.025 ng/mL
NT-ProBNP >1,800 pg/mL, and FLC-difference >18 mg/dL
4 stages (I, II, III, IV) with 0, 1, 2, and 3, risk factors respectively. ascopubs.org/doi/10.1200/JC… @myelomaMD
3 risk factors:
Cardiac Troponin T >0.025 ng/mL
NT-ProBNP >1,800 pg/mL, and FLC-difference >18 mg/dL
4 stages (I, II, III, IV) with 0, 1, 2, and 3, risk factors respectively. ascopubs.org/doi/10.1200/JC… @myelomaMD
3) Mayo 2018 Risk Stratification for smoldering multiple myeloma. The 20-2-20 system.
3 risk factors:
Bone marrow plasma cells >20%
M spike >2gm/dL
FLC ratio >20
nature.com/articles/s4140…
3 risk factors:
Bone marrow plasma cells >20%
M spike >2gm/dL
FLC ratio >20
nature.com/articles/s4140…
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