A thread for #MECFS, & related, research papers from w/c 25th Jan.
Links will be to our forum discussion threads, where abstracts, links to paper, analysis and discussion can be found. Inclusion in this list does not equal recommendation.
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"In-Depth Analysis of the Plasma Proteome in ME/CFS Exposes Disrupted Ephrin-Eph and Immune System Signaling" by Hanson et al
Short report: "Exosome-associated Mitochondrial DNA is Elevated in Patients with ME/CFS and Stimulates Human Cultured Microglia to Secrete IL-1β" by Theoharides et al.
"The Reification of the Clinical Diagnosis of ME/CFS as an Immune and Oxidative Stress Disorder: Construction of a Data-Driven Nomothethic Network and Exposure of ME/CFS Subgroups" by Maes et al.
“Updating the National Academy of Medicine ME/CFS prevalence and economic impact figures to account for population growth and inflation” by Jason & Mirin.
A thread for #MECFS, & related, research papers w/c 11th Jan.
Links will be to our forum discussion threads, where abstracts, links to paper, analysis and discussion can be found. Inclusion in this list does not equal recommendation.
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"Reversible widespread brain 18F-FDG PET hypometabolism in chronic fatigue syndrome treated by hyperbaric oxygen therapy" by Guedj et al.
Independent re-analysis of the the largest trial that claims benefits of GET and CBT.
"The modest treatment effects obtained on self-report measures in the PACE trial do not exceed what could be reasonably accounted for by participant reporting biases."
A 2017 analysis of patient surveys by @keithgeraghty shows GET is rated negatively by the majority of patients (54%–74%), while pacing "is the most favoured treatment with the lowest negative response rate and the highest reported benefit (44%–82%)."