Indiana University Infectious Diseases Fellowship
6 Feb,
13 tweets, 6 min read
#idboardreview 30 F from India 🇮🇳 b/l pedal edema, 24h total protein >3g, normal kidney biopsy, intermittent milky white urine, no dysuria. Pic (seen in urine). Diagnosis? #medEd #idmedEd #IDtwitter 
#microfilariae can cause glomerular dz
direct physical invasion or
as an immune mediated (mesangiocapillary GN, mesangioproliferative GN, membranous GN or collapsing variant of FSGS)
direct physical invasion or
as an immune mediated (mesangiocapillary GN, mesangioproliferative GN, membranous GN or collapsing variant of FSGS)
#Chyluria in filariasis is usually associated with abnormal retrograde or collateral flow of lymph from intestinal lymphatics into the renal lymphatics.
#chyluria ddx filariasis, echinococcosis, schistosomiasis, ascariasis, tuberculosis, malignancies, postoperative state (trauma to lymphatics or thoracic duct during surgical procedure
#wucheria lifespan of adult worms 4-5 years; however, chyluria can be observed after >10 years. Possible reasons for this phenomenon include: (1) irreversible damage to the lymphatic duct (2) the longer survival of adult worms and (3) a non-filarial etiology
Fat intake, pregnancy and exercise are considered to be aggravating factors of chyluria #wucheria
Treatment of #Wucheria bancrofti high-protein diet without fat-containing foods plus diethylcarbamazine (DEC) xtwo weeks. Conservative treatment of lymphatic filariasis includes bed rest and a fat-restricted diet
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