#idboardreview 30 F from India 🇮🇳 b/l pedal edema, 24h total protein >3g, normal kidney biopsy, intermittent milky white urine, no dysuria. Pic (seen in urine). Diagnosis? #medEd #idmedEd #IDtwitter Image
#microfilariae can cause glomerular dz
direct physical invasion or
as an immune mediated (mesangiocapillary GN, mesangioproliferative GN, membranous GN or collapsing variant of FSGS)
#Chyluria in filariasis is usually associated with abnormal retrograde or collateral flow of lymph from intestinal lymphatics into the renal lymphatics.
#chyluria ddx filariasis, echinococcosis, schistosomiasis, ascariasis, tuberculosis, malignancies, postoperative state (trauma to lymphatics or thoracic duct during surgical procedure
#wucheria lifespan of adult worms 4-5 years; however, chyluria can be observed after >10 years. Possible reasons for this phenomenon include: (1) irreversible damage to the lymphatic duct (2) the longer survival of adult worms and (3) a non-filarial etiology
Fat intake, pregnancy and exercise are considered to be aggravating factors of chyluria #wucheria
Treatment of #Wucheria bancrofti high-protein diet without fat-containing foods plus diethylcarbamazine (DEC) xtwo weeks. Conservative treatment of lymphatic filariasis includes bed rest and a fat-restricted diet

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