Some good news for your evening! Now that it’s finally out I can share! Our updated mRNA-1273.351 Moderna vaccine is on its way to NIH to be tested in early stage clinical trials to determine if it can be used as a booster shot against variant B.1.351 (South Africa strain)!
Yes. We had this ready to go in 30 days. Working hard!
You can find more here: businesswire.com/news/home/2021…
You can find more here: businesswire.com/news/home/2021…
Just so you guys have an idea on the approaches to boosting we are evaluating (also note that while YES, our vaccines do provide neutralizing activity against VOCs we are choosing to do these studies out of an abundance of caution and stay ahead): 
Moderna is also increasing the 2021 base plan to 700 million doses and are working to supply up to 1 billion doses this year for the states. In addition, we are expected to increase global 2022 capacity to ~1.4 billion doses of our vaccine assuming a 100 μg dose.
In addition, there is a plan to study a dose range of 50 μg & lower for variant-based boosters & an additional booster of mRNA-1273. If the effective dose for a booster is 50 μg, then the 2022 supply could be significantly higher than 1.4 billion doses. Lastly, Moderna is looking
to add more doses to each vial of our vaccine, and we are pursuing a plan that may allow up to 15 doses to be drawn from each vial. This would greatly expedite production and delivery of additional doses! investors.modernatx.com/news-releases/…
Pfizer is initiating a study to evaluate the safety and immunogenicity of a third dose of their vaccine as well as an updated variant specific booster in an abundance of caution for current & future VOCs. It can now be stored at normal freezer temperature!
businesswire.com/news/home/2021…
businesswire.com/news/home/2021…
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