Alina Chan Profile picture
24 Mar, 22 tweets, 6 min read
Please no one ever ask me again why it's important to find the origins of a pandemic...

"... governments and scientists agree that deciphering the creation story is key to reducing the risk of future pandemics."

bloomberg.com/news/articles/…
Unfortunately, the author @jwgale goes straight to HIV from the 1920s...

How many people do you know who were alive in the 1920s?
We cannot keep talking about how things were done literally 100 years ago.
When SARS1 broke out ~2 decades ago, Guangdong CDC contact traced "clusters of cases in six other municipalities from November 2002 to mid-January 2003. On February 3, 2003, province-wide mandatory case reporting of atypical pneumonia.. instituted..."
ncbi.nlm.nih.gov/pmc/articles/P…
In contrast, for SARS2, there was almost zero interest in contact tracing to find earlier clusters or the intermediate hosts.
The article fairly points out that the WHO-China team is half constituted by researchers from China.

Although it is unknown if their report will ever be released and how scientists will respond to it.
"Other groups, including an expert panel convened by the medical journal The Lancet called the Covid-19 Commission, are also probing the virus’s origins."

I think you should have pointed out that Peter Daszak is leading this origins study by the Lancet...
What this means:

THERE IS NO (publicly known) CREDIBLE INVESTIGATION OF THE #OriginsOfCOVID

wsj.com/articles/the-w…
Scroll to point 6. What role did the market play?

ZERO animal samples positive.

Any of the few environmental samples positive (genetic evidence) pointed to human introduction of the virus to the market.

Epidemiological evidence pointed to outbreak preceding the market cluster.
Furthermore, if you look at SARS1, the animal traders were the people with a good level of immunity against SARS viruses. Even though only 2 animal traders were ever diagnosed with SARS1 in the clinic, a whopping 20-40% of animal traders had antibodies against SARS viruses...
In contrast, for SARS2, the market animal traders were the among the first to get hit. Suggesting that there wasn't a good % with immunity.
I've also seen this suggestion repeated among people who should know better: "it’s possible that not enough samples were taken."

Do you believe that China would be lazy enough to not collect enough samples to trace a dangerous pathogen that emerged in one of their top cities?
I guess China decided to wait for these amazing 17 international experts to show up to tell them how to investigate the origins of a dangerous pathogen that was first detected in China.
Point 10. "The WHO mission said further research should involve tracing these products to their source and testing other animals there, as well as their surroundings and people living nearby."

China left this as homework assignment for the WHO-China team. 1+ year after outbreak.
On point 12, the article does good in pointing out that "Chinese authorities refused to make available raw data on the (suspected early COVID) cases because of patient privacy concerns" but doesn't challenge whether this is a plausible situation 1 year post-covid.
Scientists: Should we ask donors if we can check their 2019 samples for COVID? So we can find out when this all really started and if there are possible sources leading to future outbreaks?

Other scientists: Nah.
Point 13. "The WHO team is still pressing Chinese officials to conduct exhaustive tests on stored blood-donation samples from Wuhan in 2019, which might indicate whether the virus was present there earlier."

WHO independent experts: Can you please check it though?
Please don't call them the WHO mission scientists. This is a WHO-organized half Chinese half independent expert team.

I don't know if the @WHO actually endorses their proposal:
What is the hypothesis here? That a magical unique bat virus travelled from the glorious land of SE Asia all the way to Central China, outside the SARS spillover zone, without leaving any traces along the way (presumably frozen), and this single virus won the pandemic lottery?
This is like: (Wo)Man plays lottery in country where (s)he isn't a citizen for the very first time, miraculously wins $100M prize, must be transferred to country of residence without incurring any transfer fees.
In case it’s unclear to anyone. I’m waiting for the WHO-China report.
Seasons 7-8 never happened.

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More from @Ayjchan

23 Mar
I have a hunch that the lab leak hypothesis is going to really go mainstream this week.

So I hope that science communicators will take it up on themselves to help the public process this information in a rational and non-alarmist way.
I’m hoping that most of the discussion going forward will be about how we can mitigate the risk of lab pathogen pandemics and quickly trace the origins of future outbreaks.

As opposed to “look at all the racists and conspiracists who said covid-19 came from a lab.”
If scientists & science communicators don’t fulfil this essential role of explaining how pandemics can emerge from various types of research activities, it’s a guarantee that less informed people will.

You can’t not do the work and then complain less qualified people did it.
Read 6 tweets
22 Mar
I kind of expected this day to come, but still surprised that it actually arrived.

I'm going to do a quick FAQ🧵 for the public (both scientists & non-scientists) who are just hearing about the possibility of COVID-19 / SARS-CoV-2 having emerged from lab or research activities.
Is it racist to ask whether COVID-19 emerged from a lab or from the wildlife trade in China? No.

Have racist people asked the question above? Yes.
More importantly, will people call you a racist if you ask whether COVID-19 emerged from a lab or from the wildlife trade in China?

Unfortunately, yes, it is quite likely they will call you a racist and more.

And yes, even if you're Asian, you could be called a race traitor.
Read 12 tweets
22 Mar
Thank you to experts independently calling for proper investigation of possible lab origins of COVID-19. Not an exclusive list, alphabetically by surname:
@jbloom_lab @canardbruno @DecrolyE @R_H_Ebright @DFisman @FilippaLentzos @mlipsitch @ras_nielsen @vaxine_news @DavidRelman
Sincere thanks to @jbloom_lab who has taken a lot of heat recently for raising the lab leak hypothesis and for defending me, a “conspiracy peddler” according to some scientists.
Also many thanks to @canardbruno and @DecrolyE who have been publicly discussing the lab leak hypothesis and were among the first to point out the unique furin cleavage site and why it is concerning that it was missed in the WIV’s first papers on COVID-19.
Read 14 tweets
21 Mar
Going to do a serious thread on the new TWIV episode released today because it raises so many commonly held opinions on why #laborigins #labescape of COVID-19 was (extremely) unlikely.

Start ~27:20 min mark...
microbe.tv/twiv/twiv-734/
I'm very, very glad that TWIV gets the obvious strawman out of the way immediately.

Very few experts - I can't think of any off the top of my head - are claiming that SARS2 was completely, magically designed from no similar virus in nature.
At the ~32:47 min mark, TWIV says "the dialogue has slowly shifted from it was made in a lab.. now it escaped.. How do we deal with that?"

I was surprised because in their June 2020 podcast, their guest says lab escape is a classic conspiracy theory.
Read 18 tweets
21 Mar
Got a clue for the #OriginsofCOVID #PopsicleOrigins hypothesis:
At the 15:00 min mark Peter Daszak says they’ve got really good cold chain from remote sampling sites back to the labs - at least 16,000 bat samples collected.

Finally found a source of the myth going around that 3% of people in Yunnan have SARS antibodies and millions of people are getting bat viruses each year. This is a miscommunication. See the actual paper only surveying people living close to caves where SARS detected...
In contrast to the interview, the paper says “2.7% seropositivity for the high risk group of residents living in close proximity to bat colonies suggests that spillover is a relatively rare event” albeit some sero(+) could’ve faded in this high risk group.
ncbi.nlm.nih.gov/pmc/articles/P…
Read 10 tweets
17 Mar
Chatted with @schmidtwriting for his new @undarkmag article on the traps and dangers of advocating for an investigation into potential lab origins of covid-19. #laborigins #OriginsofCOVID
I think this piece by Charles @schmidtwriting was particularly well written because of how balanced it is. There were parts that I didn't like and had to grapple with. A lot has happened in the last year since I started looking into the evidence surrounding the #OriginsofCOVID
It comes at a time when the WHO-China team is expected to release their full report in the coming week(s). And @JamieMetzl and ~two dozen scientists (me too!) have posted a letter in the @WSJ pointing out major major flaws in the WHO-China not-an-investigation joint mission.
Read 22 tweets

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