One of the world's leading virologists, @RobertoBurioni, added a new role 5 years ago—taking on anti-science. There's so much we can learn from him. Our conversation (and transcript) here, w/ @cuttingforstone @Medscape medscape.com/viewarticle/94…
We discussed the variants, vaccines, and, notably, their potential for blocking asymptomatic transmission. Lots of optimism (which we need!): Image
Why did he take on the role of dealing with science skeptics and the anti-vaxxers? Image
This profile of Professor Burioni @ScienceMagazine is really is worth your while to take in and understand what he has been up against, and what he's been able to accomplish
sciencemag.org/news/2020/01/i…

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More from @EricTopol

2 Apr
What a good Friday!
First 4.0M vaccine day in the US
Hitting 4.0 M in a day gets the average now to 3.0M
bloomberg.com/graphics/covid…
CDC tally from this morning
Approaching 40% of adults, 75% of seniors, with at least 1 dose
This represents awesome progress
Read 4 tweets
1 Apr
Not exactly. You can be vaccinated and carry the virus (carrier). But if the viral load is so low you can't transmit (not a transmitter) spread is blocked and we move onto the pandemic exit ramp.
No transmitters, no 😷s
Read 5 tweets
25 Mar
How to be a superhuman vs. #SARSCoV2?
Get vaccinated
Why do you become a superhuman?
1. Levels of neutralizing antibody for vaccine >> natural infection
2. Protection w/ vaccine additive to prior infection
3. Protection vs. variants: vaccine > natural immunity
4. Less reinfection
Read 6 tweets
24 Mar
How do you know that B.1.1.7 is dominant in Michigan?
When it has its highest number of new cases in a day in over 3 months
Image
Just as was seen in Israel, vaccination protection for older individuals with case and hospitalizations predominantly in younger, non-vaccinated. And reminder: the vaccines work very well vs B.1.1.7 freep.com/story/news/loc…
A big boost in vaccine distribution and support for administering mass vaccination in Michigan is warranted ImageImage
Read 4 tweets
23 Mar
Very good news @NEJM today on vaccine effectiveness in the US and Israeli healthcare workforce
1. @UTSWNews health system over 23,000 employees, 70% vaccinated, had a dramatic reduction of infections
nejm.org/doi/full/10.10…
2. And similarly @UCSDHealth @UCLAHealth over 36,000 health care workers were vaccinated nejm.org/doi/full/10.10…
3. And concordant with a 3rd report of vaccinations among health care workers in Israel nejm.org/doi/full/10.10…
Read 4 tweets
23 Mar
This @AstraZeneca statement in response to the @NIH press release is unacceptable. They know exactly what is going on w/r to the time cutoff for 1° analysis, which appears to be at odds with the independent Data and Safety Monitoring Board. It should not take 48 hrs to sort out
The DSMB, consisting of 11 independent experts who have been overseeing the trial from its outset through its completion, says the primary analysis showed efficacy between 69-74%. Let's see all the data @AstraZeneca washingtonpost.com/world/astrazen…
Let's be clear. This is *not* about the vaccine. It is about @AstraZeneca, their own worst enemy, with an apparent breach of integrity on data dissemination. And where is the @UniofOxford on this, their partner?
Read 5 tweets

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