Co-infection is bad news—Scientists in Brazil have identified two cases where people were simultaneously infected with two different variants of #COVID19. Co-infection raises the likelihood of *recombination* admixture that generates more variants. 🧵
cnn.com/2021/03/11/ame…
2) According to the study, co-infection raises the possibility of recombination of the genomes of the different strains, which can generate new variants of the coronavirus.
3) "Although there are a few reported cases of reinfection, the possibility of co-infection by E484K adds a new factor to the complex interaction between immune response systems and SARS-CoV-2 Spike mutations," wrote the authors.
4) ICUs and hospitals across the country are nearing capacity, and governors, state health secretaries, and mayors are calling for more restrictive measures to contain the spread of coronavirus.
5) On Thursday, Sao Paulo state's Governor Joao Doria announced new emergency lockdown measures in Brazil´s richest and most populous state.
"Brazil is collapsing," he said in a video released moments before a press conference about the new measures
6) Variants galore. Crazier is that somehow #B117 maybe has been outcompeted in India. If so, this would be huge and concerning.
7) So what is virus recombination anyway and why is it more dangerous for generating variants? It allows viruses to swap entire sections of their genes. This is like trading notes on large scale (instead of figuring it out randomly by itself).

See this thread🧵 explained below.
8) Seems the Indian #B1617 double mutation variant is now surging in the UK 🇬🇧 as well. As is the SA #B1351 too.

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More from @DrEricDing

20 Apr
An airplane janitor staff in Auckland🇳🇿 airport, who cleans planes “that flew internationally”—is positive for #COVID19 in weekly testing. 2x-Pfizer vaccinated, family neg, the cleaner’s job is “non-public facing”. Plane aerosol transmission?

(@WicMar ht)
health.govt.nz/news-media/med… Image
2) NZ health authorities add “The person has been fully vaccinated—received two doses of Pfizer/BioNTech vaccine early in the vaccination campaign—in February and March. We know the Pfizer vaccine is highly effective, but at 95% effectiveness a small number may not be protected.”
3) “Breakthrough infections happen with all vaccines. This shows us how important it is that as many New Zealanders as possible take up the offer to receive vaccine when offered it and are protected. The more people that are vaccinated, the more protected we will all be.”
Read 17 tweets
19 Apr
✈️ Outbreak—47 positive #COVID19 of a 188 seat Vistara flight from New Delhi to Hong Kong have tested positive, after all tested negative 72 hours prior. The scariest thing? Only 8 detected before began quarantine. 39 only identified later during hotel quarantine, 22 at day 12!🧵 Image
2) If it weren’t for hotel quarantine—Hong along would have completely allowed these 39 to have begin spreading in the community! This is why border quarantines critical. google.com/amp/s/www.ndtv…
3) Even more scary detail, of the 47 cases, 22 of the cases were only discovered on day **12** of the hotel quarantine testing!!!

Ummm, what if—14 days might not be enough to find and block all border entry?

onemileatatime.com/flight-coronav…
Read 9 tweets
19 Apr
The new “double mutation” variant from India 🇮🇳 #B1617 is surging fast in UK—5x increase in % of #COVID19 cases in just 2 weeks. Same with the South Africa 🇿🇦 #B1351 variant. When did they increase? After schools reopened.

And keep in mind—it’s rising despite high vaccinations. Image
2) How does the India variant compare to #B117? It seems to be increasing faster than any other variant in the UK. It’s outcompeting it. Image
3) I know the variants are getting hard to keep track. But here is a handy shortcut info graphic. Image
Read 11 tweets
19 Apr
Yup—“Canada’s #COVID19 travel restrictions are an inept, deadly failure”

There is a reason #P1 found Canada 🇨🇦 to easily infiltrate. And good reason 30,000 truck drivers cross the US-Canada border every single day without restrictions. Poor leadership.
theglobeandmail.com/canada/british…
2) Just how lackadaisical is Canada 🇨🇦? This lax.
Read 9 tweets
19 Apr
VACCINE CARD FRAUD—it has begun. eBay lists an “Authentic CDC Vaccination Record Card” for $10.99, sold by a pharmacist in the Chicago area. It’s illegal, federal regulators say. But he has sold 100+ already, reports @ddiamond. #COVID19 #CovidVaccine
washingtonpost.com/health/2021/04…
2) the problems is that the card itself is genuine. That’s what makes this hard when people secretly resell these untracked blank vaccine cards. Without any public registry to verify, we won’t know. We need a registry!
3) “The listings are a “perfect example” of burgeoning scams involving coronavirus vaccination cards that could undermine people’s safety, as well as the success of the nation’s largest mass vaccination effort, said North Carolina Attorney General Josh Stein.
Read 16 tweets
19 Apr
Let these sink in—

📍Black women with college degrees are more likely to see their babies die as infants than a White woman without a high school degree.

📍Black alumni of @Yale in 1970 are >3x time more likely to die prematurely than White classmates.
2) Racial discrimination correlates with serious health problems, says Harvard professor David Williams. More here: cbsn.ws/32r6LSc
3) “there were 32 African Americans in the original class of 1970, almost exactly 3 percent of the total class. But nine of us had died, more than 10 percent of the total, which meant we were dying at more than three times the rate of our white alumni”
theroot.com/yale-grad-my-c…
Read 4 tweets

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