Thread by @_oatc_

@JonRonson9 @LastBehaviorist @SamHarrisOrg 1/ Yes, but none of us got a user manual at birth, so we have to see what emerges & try to communicate that in the words available at the applicable age. The research Sapolsky cited only had brain tissue of those dead by the late '70s, long before any were out as non-binary…

@JonRonson9 @LastBehaviorist @SamHarrisOrg 2/…so none were included, but the range of neuron numbers across the totality of subjects & controls suggests that people can be intermediate; this might account for those unsure until later & non-binary identities. Unfortunately, no other country has ever bothered to…

@JonRonson9 @LastBehaviorist @SamHarrisOrg 3/…collect carefully documented brains of trans people, & even 🇳🇱 stopped, due to the backlash, so there's no prospect of further replication. Very high-resolution MRI scans could now pick up the size difference, in the living, but no one seems to want to do such solid research.

@JonRonson9 @LastBehaviorist @SamHarrisOrg 4/ Since that research🖼️ it is now known that the BSTc is irreversibly gendered in the first months, if not before, by androgens (so hormones later in life could never have had an effect), but epigenetic (DNA but not genes) differences🖼️ or chemicals can block/mimic that

@JonRonson9 @LastBehaviorist @SamHarrisOrg 5/ This, & how trans adolescent's dysphoria increases with the natural hormones of puberty, & how trans people respond to "cross-sex" HRT, all fits the (almost universally accepted in mammalian research) Organisational-Activational Hypothesis of the action of "sex" hormones…

@JonRonson9 @LastBehaviorist @SamHarrisOrg 6/…in the brain proposed in 1959⬆️ which predicts not only reproductive responses (centred in the BSTc) & hormonal will be affected but also gendered/sexed parts of the nervous system as well as areas to which there are axonal extensions, all biological

https://twitter.com/_oatc_/status/1383066191133032452?s=20

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