And when you were born, on the day of your birth they didn't cut the umbilical cord, and didn't wash you with water to clean you, and at the salting you weren't salted, and at the swaddling you weren't swaddled
No eye had mercy on you, to do for you any of these things out of compassion for you, and you were cast into a field, in disgust of your soul, on the day that you were born
"Grant reviewers... deemed the plan 'outstanding.' But they gave the proposal a low priority score, dooming its bid for funding. 'The significance for developing a pan-coronavirus vaccine may not be high,' they wrote, apparently unconvinced that the viruses pose a global threat."
We will get a pancoronavirus vaccine, and it will not be in the far-distant future, either. We have the technology now (assuming no unexpected negative side effects of mRNA vaccines - so far there are none)
1. What's so special about mRNA vaccines? A thread
Viruses (and all living things) are made of proteins. Our acquired immune system works by identifying one of the proteins of a foreign invader, and producing antibodies against that specific protein
2. An autoimmune disease is when our body mistakenly identifies one of our own proteins as foreign, and produces antibodies against it
3. Until now, all vaccines were made from weakened or dead viruses, or related viruses that confer cross-immunity. Cross immunity can occur because related viruses often share proteins. Antibodies against a protein give you immunity from all viruses that share that protein
2. In the "good old days" Silicon Valley was about understanding technology. Silicon, to be precise. These were people who had to understand quantum mechanics, who had to build the near-miraculous devices that we now take for granted, and they had to work
3. Now, I love libertarians, and I share much of their political philosophy. But you have to be socially naive to believe that it has a chance in a real society. In those days, Silicon Valley was not a real society. It was populated by people who understood quantum mechanics
1. For years I have been astounded at the lax attitude the US has toward election fraud. Elections that take days. Ballots moved around. One of the reasons is that I have seen a much better system, the system that is used in Israel. This is thread describing the Israeli system
2. First of all, scale. Israeli polling stations are tiny by US standards. In 2015 I wrote down the stats to myself, they haven't changed much since: There are 10,119 polling stations for 5,883,365 eligible voters. That's 581 people per polling station
3. Most of the polling stations are rooms in schools. A single school might have dozens of polling stations, each in its own room. When I lived in a village, the polling station was in the community center, and there was only one polling station for the whole village
I find the Swiss data the most convincing. German, French, and Italian rates are in the exact order that you would expect
The difference between German and Italian rates *within* Switzerland are a factor of 10, similar to the difference between Germany and the US, @ScottAdamsSays. That is much more of a mystery than comparing two separate countries!
This is the podcast on Covid self-tests that you have to hear. It answers all your questions. Takeaway: It's the bureaucracy, stupid! Only 21 minutes, and Gladwell is an excellent interviewer. My notes are below
Mina: It's been first and foremost a regulatory hurdle
The only paths we have to evaluate tests like this in the US are medical diagnostic pathways. They're pathways designed specifically to ensure that a physician, like a detective, is getting all of the information they need to diagnose a sick person in front of them