Post-acute Covid Syndrome. (Thread)
Persistence of symptoms and/or development of complications beyond 4 weeks from the onset of acute symptoms.

@HaryaxPathak @ProfSomashekhar @neoarchana @neoarchana @pankti4299 @AlishaAkhani @hard_dil @shreya__kataria
It has 2 categories
A) Subacute or ongoing (4-12 weeks)
B) Chronic or post-Covid (beyond 12 weeks).

Why does it occur?
Cellular damage, cytokine storm and pro-coagulant state.

#MedTwitter #LongCovid
Some reports suggest that the residual effects might include fatigue, dyspnea, chest pain, cognitive disturbances, arthralgia, anxiety, depression.

Investigations that can be done - ECG, Echocardiography, D-Dimer, Pulmonary function test, CT, EEG, Psych elav.

Cardiovascular effects also include increased cardiometabolic demand and fibrosis.

Hematologic effect according to certain retrospectives studies is a hyper-coagulable state, but there is varied duration of hyperinflammation.

#MedTwitter #LongCovid
Neuropsychiatric - may include headache, anxiety, depression, PTSD, dysautonomia, brain fog.

Renal - reduced eGFR has been reported
at 6months follow-up.

@DevPalkar @pankti4299 @HaryaxPathak

#MedTwitter #LongCovid #COVIDEmergency
Endocrine - new or worsening of diabetes. Patients with newly diagnosed DM without any risk factor, HPA axis supression or hyperthyroidism should undergo proper clinical investigation under an endocrinologist.

Dermatologic - Hair loss has been reported in 20% Covid-19 pts.
Gastrointestinal - Prolonged viral fecal shedding can occur in COVID-19 even after negative nasopharyngeal swab testing. May even alter gut microbiome.

#MedTwitter #LongCovid #COVIDEmergency

Here is in infographic summarising everything.
This is a summary thread of an excellent review article published in nature medicine.…

@HaryaxPathak @ProfSomashekhar @neoarchana @pankti4299

#MedTwitter #LongCovid #COVIDEmergency

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More from @DrBinoyVShah

1 May
@neoarchana @ProfSomashekhar @HaryaxPathak @DevPalkar @pankti4299 @AlishaAkhani
There is certain evidence that people with high vaccine scepticism most of the time overestimate the probability of rare vaccine-related negative events especially mortality related events
and sometimes correlate them to negative events which do not have to do anything with the vaccine. This shifts their risk-benefit balance! It is also influenced by the kind of information they consume and the source of that information.
Sometimes this anti-vaccine movement is started by religious believers who then go on to influence people of the society using religion and again overestimating the rare negative events. they do not spare anyone - rich, poop, educated or illiterate, a child or an adult!
Read 6 tweets

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