This is a stupid part of NY reopening—“if restaurants put up physical barriers between tables, in which case they don't need to worry about the six foot rule.” 🤦🏻♂️— hello… it’s an airborne virus!!! #COVID19
2) VENTILATION is key. Both ventilation and masks needed to reduce risk indoors. But most buildings not ventilated well enough.
3) “Until we recognise that #COVID19 is airborne we are setting ourselves up for repeated failure”
4) How is aerosol different from large droplets? aerosol study indicates that coronavirus is persistent and stable for many hours. Typical air exchange every 20 min to 4 hrs, depending on ventilation. #COVID19
5) Now that aerosol transmission of the coronavirus is established, we need to disperse aerosols quickly. Key is ventilation. 🇯🇵 assumed it was airborne from the beginning. Here is how to ventilate your school classrooms if unable to open window. #COVID19
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📍GET BOTH DOSES! Great variants & #COVID19 vaccine news—Pfizer/BioNTech vaccine had great efficacy of 89.5% vs #B117 🇬🇧 variant & 75% vs #B1351 🇿🇦 variant for infection—but only with 2 doses. The 1 dose efficacy was just ~29% vs #B117 & ~17% vs #B1351. 🧵 nejm.org/doi/full/10.10…
2) “Viral genome sequencing conducted from February 23 through March 18 indicated that 50.0% of cases of Covid-19 in Qatar were caused by B.1.351 and 44.5% were caused by B.1.1.7. Nearly all cases in which virus was sequenced after March 7 were caused by either #B1351 or #B117.”
3) To be clear—this was not a trial, but an observational case-control study. “Vaccine effectiveness was estimated with a test-negative case–control study design, a preferred design for assessing vaccine effectiveness against influenza (see the Supplementary Appendix).”
📍VARIANT TAILORED VACCINE—Moderna announced that a variant-tailored 3rd dose of the NIH-Moderna vaccine greatly boosted antibody levels in volunteers in a new study. The updated vaccine, tailored against the #B1351 variant from 🇿🇦, worked best.🧵 #COVID19businessinsider.com/modernas-boost…
2) Earlier research, done in petri dishes, suggested the B.1.351 variant was able to partially reduce the effectiveness of leading vaccines, including from Pfizer and Moderna. businessinsider.com/coronavirus-va…
3) How much did the #B1351 variant decrease neutralization from Pfizer and Moderna vaccines? A lot. 20-30x fold drop for Moderna. And 30-40x fold drop for Pfizer - akin to a completely unrelated distant bat coronavirus. While not equal to efficacy, this is a big drop. See 🧵
Biden waives the vaccine patents. Saving humanity is more important than protecting corporate IP, which taxpayers paid for with our research dollars anyway.
2) Previously, the Trump WH had *blocked* patent waivers where it was first proposed in October 2020!! Let that sink in how much elections matter! washingtonpost.com/health/2021/05…
3) Been yelling about this for weeks. 50 companies stand ready to produce the vaccines. But to fully produce it, the pharma companies need to assist in technical sharing too. We can’t let pharma off the hook.
2) The Biden administration supports temporarily lifting intellectual property protections for coronavirus vaccines and will move forward with international discussions to waive them, its top trade negotiator said on Wednesday.
3) “This is a global health crisis, and the extraordinary circumstances of the COVID-19 pandemic call for extraordinary measures… in service of ending this pandemic, supports the waiver of those protections for COVID-19 vaccines,” U.S. Trade Representative Katherine Tai said
Incentives—will a free drink or a $100 payment actually convince anyone to get #COVID19 vaccinated? Maybe, but “It gets at the low-hanging fruit”—people who aren’t actively opposed but may have been too busy to make an appt.
2) “West Virginia is offering $100 savings bonds to 16- to 35-year-olds who get vaccinated. Maryland will pay fully vaccinated state employees $100. Breweries participating in New Jersey’s “Shot and a Beer” program are giving out free drinks to legal adults who gets vaccinated.
3) “Connecticut and Washington, D.C., are also running free-drink promotions for the inoculated. Harris County, TX, approved $250,000 for vaccine perks like gift cards and freebies. Detroit is handing out $50 prepaid debit cards to those who drive a neighbor to a vaccine clinic.