A pandemic is not a time for moral grandstanding and PR spin but we've gotten a double dose of each when faced in Canada with the choice of vaccinating with AstraZeneca to prevent #COVID19 1/16
Public Health and public figures pushed AstraZeneca at a time when vaccines were scarce and variants and cases were surging, telling Canadians it was their duty to take AZ first if that was the 1st vaccine available. 2/16
But messaging shouldn’t trump math when fighting an enemy whose spread threatened to overwhelm the capacity of our hospitals to treat all acutely ill patients. 3/16
The messaging was based on a faulty premise: That by taking on the risk of AstraZeneca, Canadians were willing to sacrifice themselves as individuals for the broader, public good. 4/16
The messaging was also based on bad math: Public Health lowballed the risk of AstraZeneca and was slow to adapt risk assessment to emerging data from other countries. 5/16
When the math is corrected, this is clear: For some, the risk of critical illness is greater from AstraZeneca than from COVID19. For them, getting AZ increases personal risk AND places a greater burden on our hospitals since they are more likely to end up in an ICU. 6/16
It’s never been a question of choosing between individual risk and public good -> when the math is right, the goals are complimentary. 7/16
Other countries get it.
In the UK, birthplace of AstraZeneca, public health excluded those under age 30, and then later, those under age 40. 8/16
But in Canada, some who pushed the patriotic narrative seem focused on making sure those who heeded that advice don’t feel bad. They again are focused on the message at the expense of the math and science that protects us. 9/16
Some of those ‘message over math’ folks warn that if we say some vaccines are worth the wait for some people, we undermine confidence in vaccines and grow resistance to getting vaccinated. The opposite is true… 10/16
When messaging trumps science, we undermine public confidence in public health, we seed doubt and we increase hesitancy. It was false messaging that dug this hole and more of the same will dig us deeper. 11/16
Is it likely the case that AstraZeneca now is better than an mRNA later for some people but not others? That’s what many mathematical models shows. 12/16
As for those who took AstraZeneca not only to protect themselves but because they believed the public messaging that doing so protected the broader community too, they should be praised – they had reason to believe they were serving the public good. 13/16
But those who shaped the messaging should take time to reconsider. Don’t dumb down public health messaging. Canadians are smart enough to understand nuances and this pandemic has taught many about the nature of science and evidence. 14/16
Shape your messaging with the same principles that underlie good science: Be honest, transparent and adapt to changing evidence and circumstances. 15/16
Remember too that Canadians are patients and deserve to know enough about options so that their choices are based upon informed consent. 16/16

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More from @SherOnHealth

24 Apr
Real-world American study of 91,134 people finds one dose of Pfizer/Moderna protects MUCH LESS against death/hospitalization then two doses in 3 or 4 week intervals.
The finding should raise questions about Canada delaying doses 16 weeks.

1/X

medrxiv.org/content/10.110…
Some health officials, including @Healthmac defend the delay pointing to a less robust study that counted as one-shot immunized those who had a dose but who were hospitalized or died before the two weeks that shot needs to build an immune response but now the verdict is in...
2/X
The new study did NOT count people as having gotten one dose unless they were fine for 2 weeks before illness began. Those who got sick in the first two weeks were counted as not vaccinated at all. The one-dose group was limited to those who were health 2+weeks after 1st dose
3/X
Read 9 tweets
11 Mar 20
1/2 Public Health and private vigilance in Ontario is our 1st line of defence against #coronavirus If it falls short, we face a crisis. Epidemiologists estimate between 40 and 70% of adults will eventually get coronavirus. Even at the low end, that's 4 million people infected.
2/2/a If we borrow data from China, 20% of those infected needed hospitalizations. That works out to 800,000 hospitalizations in Ontario. Even if we cut that in half, that's 400,000 needing spaces in hospitals already so full, patients are treated in hallways ...
2/2/b So public health and private vigilance must slow the spread so hospitalizations gets stretched out over many months.
My analysis springs from that for Massachusetts by director of the @HarvardGH @ashishkjha - but #onpoli bed shortage is much worse

shorturl.at/nOXY3
Read 5 tweets
4 Mar 20
1/4 #SuperTuesday -
(1) @JoeBiden is frontrunner, having swept the South, even edging @BernieSanders in Latino-heavy Texas, beating @BernieSanders twice in his New England backyard, winning in the prairies in Oklahoma and GOP-dominant Alaska and keeping close behind in California
(2) If this dynamic continues, Biden will win the nomination by a comfortable margin; the only places I seeing him getting beat by Sanders is the Sunbelt, where Bernie has won Nevada, Colorado and Utah, and perhaps the Pacific Northwest. Everyplace else is Biden land.
(3) That's a BIG "if" as dynamic can and do change. Now that Biden is frontrunner, he becomes the focus. He has a lengthy political history to attack and has shown himself vulnerable on the hustings by his struggles to speak clearly. The next debate, he will be under full assault
Read 7 tweets

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