Troubling—the worst variant to date, the #DeltaVariant is now the new fastest growing variant in US. This is the so-called “Indian” variant #B16172 that is ravaging UK 🇬🇧 despite high vaccinations because it has immune evasion properties. Here is why it’s trouble—🧵. #COVID19
2) We are expecting the #DeltaVariant to continue growing in the US, outpacing all other variants just like it has in India 🇮🇳 and UK 🇬🇧, and become dominant in US by end of July, if not earlier.
4) the #DeltaVariant#B16172 is worrisome because study after study shows it has one of the worst antibody neutralization profiles against the current vaccines. Here it is against the Pfizer vaccine - one of the best vaccines for variants to date. 1st dose very little effect.
6) Also notice how neutralization is much weaker in the elderly—but #B16172#DeltaVariant is so bad that the neutralization in young adults (~20s) for Delta is even lower than neutralization in the elderly against the old strain! With Delta, you start like an 60-70 year old! 👀
7) Keep in mind that the #DeltaVariant#B16172 has been observed to also attack kids more than before. Here is Singapore’s warning.
10) why? Because the latest UK expert report says the #DeltaVariant leads to ~2.5x more hospitalizations than the #B117#AlphaVariant. And B117 Alpha itself is more severe than original strain too!!
11) thus how much worse is #DeltaVariant? if Delta has ~2.5x ⬆️ hospitalization risk versus #B117#AlphaVariant, which is 64% more severe than original earlier strain. Then 1.64*2.5= #Delta could have *4.1x* higher risk of hospitalization vs original! 👀
12) Does anyone honestly think the US or any country is going to do that much better than the UK 🇬🇧 which is also heavily vaccinated? Because this is #DeltaVariant grow speed in the Uk 🇬🇧
14) But but but, don’t we have good vaccines? Yes, but vaccination rates are not uniformly high everywhere in the Us. The conservative South has serious issues with low vaccination rates. Very low… see thread 🧵
15) That said, #DeltaVariant#B16172 is potentially tricker yielding a substantial jump down on the virus neutralization ladder according to studies. Because it has a lower starting neutralization, the efficacy drop can be substantial. Hence why 1 dose isn’t enough.
16) So what is the vaccine efficacy against #B16172#DeltaVariant? It’s just 60% for AstraZeneca, while 88% of Pfizer in one non-trial study. However, 1 dose (of both averaged) is just 33%. And many countries are just 1 dose vaccinated.
17) But is that enough against the #DeltaVariant? Well there’s only one country in Europe were Delta is dominant? Hint - it’s the one with the surge in cases, and also rising hospitalizations….
18) And given we know the #DeltaVariant is both more transmissible and severe (see above), the question is - is it more severe also in kids? It’s an open debate, but there are many reports from India 🇮🇳 that the #DeltaVariant might be….
20) I feel that ignoring the risks in kids has been one of the biggest blunders of many Covid denialist and minimizer scientists (after ignoring airborne). So many scientists ignored the risks in kids. History will remember who they are / were.
21) The #DeltaVariant is now causing an “exponential” rise in hospital admissions in the UK 🇬🇧— despite decent vaccination rates in UK. This means we can’t stop vaccinations until we hit 80% fully vaccinated. Until then we are vulnerable still as a society.
23) This is now the #DeltaVariant growing crisis in the UK 🇬🇧 and how they missed the creeping up numbers originally. Don’t let this happen in your country. Let UK and India be a lesson to all.
24) politicians often act too late. Scientists often too shy to shout from the roof tops early…. What you get is inaction by politicians & slow vocalization by scientists until too late.
We need to sometimes raise the alarm— because there is a critical need for early action.🙏
25) Today is a good day for the CDC to upgrade #DeltaVariant to VARIANT OF CONCERN status…
3) “Kennedy is set to announce Thursday the planned changes, which include axing 10,000 full-time employees spread across departments tasked with responding to disease outbreaks, approving new drugs, providing insurance for the poorest Americans and more”.
SICKENING—Trump’s DHS just deported a surgeon from Brown University Medical School—who is here legally on an H1B visa that doesn’t expire until 2027, and has committed no crimes. Trained in the U.S. at Ohio State, University of Washington, and Yale as a **transplant surgeon** (one of the most difficult surgical fields in all of medicine!!!), she is a highly trained doctor on kidney transplants, which cannot be easily replaced. Her phone was seized at the border. A federal judge handed down an injunction against her deportation—but she was already deported on a plane en route to Paris. Brown’s kidney transplant clinic is now strained by her deportation.
2) Full text:
PROVIDENCE — A Rhode Island doctor who had traveled to Lebanon to see her parents was prevented from re-entering the United States at Boston’s Logan International Airport on Thursday evening, her lawyer and a colleague said.
Dr. Rasha Alawieh, 34, who lives in Providence, has been working at Brown Medicine’s Division of Kidney Disease & Hypertension since last July, and she [has] been part of the transplant service at Rhode Island Hospital, according to Dr. George Bayliss, the organ transplant division’s medical director. She has been studying and working in the United States for about six years, he said Friday.
The US consulate in Lebanon had issued her an H-1B visa, which is given to people in specialty occupations requiring expertise. The visa was valid through mid-2027, said Thomas S. Brown, an attorney representing her and Brown Medicine.
Alawieh was detained when she returned to Logan airport, and family members are afraid that she is about to be deported to Lebanon, he said.
“We are at a loss as to why this happened,” Brown said. “I don’t know if it’s a byproduct of the Trump crackdown on immigration. I don’t know if it’s a travel ban or some other issue.”
He said her phone has been seized and he has not been able to contact Alawieh.
Bayliss said a lawyer filed a petition with the US District Court in Massachusetts, and Judge Leo T. Sorokin issued an order saying Alawieh should not be moved outside of Massachusetts without 48 hours notice. But he said that message apparently did not reach immigration officials in time, and a plane carrying Alawieh left for Paris.
“This is outrageous,” Bayliss said in an interview. “This is a person who is legally entitled to be in the U.S., who is stopped from re-entering the country for reasons no one knows. It’s depriving her patients of a good physician.”
A US Customs and Border Patrol spokesperson, Ryan Brissette, was not able to immediately answer questions about Alawieh on Friday evening.
Bayliss said Alawieh graduated from the American University of Beirut medical school and came to the United States for a nephrology fellowship at Ohio State University. She then landed a transplant fellowship at University of Washington and had a residency in the Yale hospital system before starting at Brown Medicine last July, he said.
“She’s really a very humble and able person,” Bayliss said. “She takes care of her patients. She is talented and thoughtful and a great addition to our division.”
Bayliss said Alawieh went to Lebanon to visit parents and planned to be gone for two weeks. He said she texted a colleague at 6:30 p.m. Thursday saying she was back in Boston, but then her family heard from immigration officials.
Dr. Paul Morrissey, surgical director of the organ transplant division at Brown University Health, said Alawieh works on getting people in Rhode Island on the list for a kidney transplants, and that’s a crucial job at a time when there has been a lot of focus on the need for kidneys and their equitable distribution.
He said Alawieh should not have had any problem traveling out of the country with an H-1B visa.
“It’s an unfortunate set of circumstances,” Morrissey said. “It’s putting a strain on our office. Her work has been exceptional.”
3) There is a new Trump ban against many countries, including tourist visa bans against all countries in the red and orange lists. This list is still tentative. And it shouldn’t have affected people with existing visas, such and the Brown kidney transplant surgeon
I’ve said it before, and I’ll say it again… once upon a time, liberals did have our own “Leftist Joe Rogan”… his name was Joe Rogan…
Here he is advocating for socialized medicine, healthcare for all, and supporting labor unions to protect workers.
2) Recall, Rogan was once pro Obama and pro Bernie Sanders, and pro Yang Gang, and anti Trump. It’s sad he has since failed to the dark side. But like Vader… maybe he can be redeemed someday and come back to the light.
Joe Rogan was also pro gay rights and pro DACA and pro helping inner city communities that suffer economic and social injustices. It’s sad what he has become. I feel we should try to pull & welcome him back someday. Everyone can be redeemed.
BREAKING—FDA suddenly cancels meeting to update next season’s flu vaccines, with zero explanations. Any delays will jeopardize next year’s vaccine supply chain.
2) Folks who follow me know that I’m no bullshitter. I criticized past pandemic response right and left, and have called balls and strikes without bias. And I often say things that doctors & epidemiologists are whispering among themselves but don’t say publicly. (Cough cough) ⬇️
3) While I don’t recommend hoarding… I think stocking up on flu antivirals, which you can obtain prophylactically (preventively) from doctors if you ask nicely why you’re high risk, can be a good idea. I know many doctors, epidemiologists and virologists who do for their family.
Doctors are debunking RFK Jr’s claim that 20 hospitalized measles cases in Texas are there for mainly quarantine. Doctors on the ground say the 20 kids hospitalized are having trouble breathing. Oh and they are all unvaccinated against measles, which RFK Jr neglects to mention.
2) RFK Jr told Trump today there’s now 2 measles deaths.