Why is 🇬🇧 extending restrictions? Because #DeltaVariant is big trouble & vaccine evasive.

UK forced to extend restriction for a month because of Delta #COVID19.

➡️ Countries can avoid lockdown if act fact.

HT to @VickiGSP & @IndependentSage experts.🧵
2) here are 6 critical ways to **avoid lockdowns** if #DeltaVariant is surging.

Video part 3:
3) the #DeltaVariant has crept up quietly in the UK 🇬🇧 until it was too late… and ignored for too long. Hospitalizations now soaring.

Here is what you need to know… see full thread 🧵 below.

Video part 1 of 3… (parts 2 and 3 above).

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More from @DrEricDing

14 Jun
So a controversial #DeltaVariant study did not find a sig 2-dose effect for Pfizer, yet still claims a significant efficacy. It also claims AstraZeneca hospitalization relative risk is lower than Pfizer—opposite last week—also from weak case control design—wouldn’t bank on it. 🧵 Image
2) This (left photo) is the standard VE formula. Yet this (right photo) is the modified calculation of VE used in this study. It requires a completely diff set of assumptions and then mashes the two different sets of numbers together. ImageImage
3) there are many assumptions in order for their formula. It’s very risky and tricky.

“Biased [vaccine efficacy] effect-size estimates arise if either condition is unmet.”

pubmed.ncbi.nlm.nih.gov/30099505/ Image
Read 5 tweets
14 Jun
⚠️Annoyed—the US CDC still does **not seem to classify the #DeltaVariant as a “Variant of Concern”**!! #B16172 is still merely “variant of interest” on @CDCgov website, updated just this weekend. Both @WHO & 🇬🇧 upgraded Delta to VOC weeks ago. CDC act now! cdc.gov/coronavirus/20… Image
2) Because this is what new cases of #DeltaVariant #COVID19 is doing in the UK 🇬🇧… US 🇺🇸 is a trouble if don’t act now
3) Is #DeltaVariant growing quickly in the Us? Yes. Hell yes. Yet CDC doesn’t rate it a VOC.
Read 10 tweets
14 Jun
Good news—Novavax protein-subunit vaccine phase 3 trial shown to to be 90.4% effective overall, 100% against moderate to severe disease. This is different type from mRNA and from AZ/J&J adenovirus vaccines, and different from inactivated types. #COVID19
nytimes.com/2021/06/14/hea…
2) Here is a good refresher on how the Novavax vaccine works. nytimes.com/interactive/20… Image
3) The protein units of the spike are harvested and then assembled together. There is no virus—just proteins linked together. Image
Read 5 tweets
14 Jun
⚠️90-96% of all #COVID19 in 🇬🇧 caused by #DeltaVariant.🧵

📍32% of all Delta cases visiting the hospital emergency room are at least 1 dose vaccinated

📍33% who are then hospitalized vaccinated

📍45% of all deaths got at least 1 shot—➡️ 29% got 2 shots.
theguardian.com/world/2021/jun… Image
2) Similar #DeltaVariant worries from a Canadian hospital— ➡️Outbreak even w/ 2 dose of mRNA vaccines—16 patients & 6 healthcare staff #DeltaVariant positive. 6/16 patients & 5/6 HCWs had received 2 doses of #COVID19 vaccine; 7 patients & 1 HCW had 1 dose cbc.ca/amp/1.6063802
Read 6 tweets
14 Jun
📍Outbreak even w/ 2 dose of mRNA vaccines—🇨🇦 hospital—16 patients & 6 healthcare staff #DeltaVariant positive. 6/16 patients & 5/6 HCWs had received 2 doses of #COVID19 vaccine; 7 patients & 1 healthcare worker had 1 dose. 1 patient now in ICU. #dontletup
cbc.ca/news/canada/ca…
2) Outbreaks of the delta variant at the Foothills Medical Centre in Calgary are sparking concern as some with both doses of the vaccine are still getting affected with the variant.
"We're scared, very concerned," said Wayne Stopa, a RN of United Nurses of Alberta Local 115.
3) "A lot of us have had the double vaccines already … and to find out people are still getting affected with the delta variants is quite concerning to all the staff."
Read 12 tweets
14 Jun
Delta variant fears coming true—@WHO_Europe director says #DeltaVariant of #COVID19 is "poised to take hold"—#B16172 evades 1-dose vaccine & “shows increased transmissibility & some immune escape” & more severe. It is exponentially ⬆️ in 🇬🇧 & 🇺🇸 too.🧵
thehill.com/policy/healthc…
2) Hans Henri Kluge expressed concern about the Delta variant, known by the scientific name B.1.617.2, pointing to recent research appearing to show it can spread quickly and infect those who have received one of two vaccine doses at higher rates than the fully vaccinated.
3) "We have been here before."

"Over the course of last summer, cases gradually rose in younger age groups and then moved into older age groups, contributing to a devastating resurgence, lockdowns and loss of life in autumn and winter of 2020. Let's not make that mistake again."
Read 10 tweets

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