Good news—Novavax protein-subunit vaccine phase 3 trial shown to to be 90.4% effective overall, 100% against moderate to severe disease. This is different type from mRNA and from AZ/J&J adenovirus vaccines, and different from inactivated types. #COVID19
nytimes.com/2021/06/14/hea…
2) Here is a good refresher on how the Novavax vaccine works. nytimes.com/interactive/20…
3) The protein units of the spike are harvested and then assembled together. There is no virus—just proteins linked together.
4) this article by @NPR @NPRHealth is misleading - the 93% efficacy “against more worrisome variants that have subsequently appeared” mostly only applies to #B117 #AlphaVariant.

Cmon NPR. npr.org/2021/06/14/100…
5) The other NYT piece even points out this about Novavax and variants: nytimes.com/2021/06/14/hea…

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More from @DrEricDing

16 Jun
DIFFERENT SYMPTOMS—‘Loss of smell’ is no longer a top 10 symptom of the new #DeltaVariant. A headache, sore throat & runny nose are now the most common. New study says catching Delta #COVID19 can feel different— "more like a bad cold" for younger people.🧵
bbc.com/news/health-57…
2) Since the start of May, we have been looking at the top symptoms in the app users - and they are not the same as they were," he says.
The change appears linked to the rise in the Delta variant, first identified in India and now accounting for 90% of Covid cases in the UK.
3) Fever remains quite common but loss of smell no longer appears in the top 10 symptoms, Prof Spector says.

"This variant seems to be working slightly differently," he says.
Read 7 tweets
15 Jun
📍1 in 4–almost a quarter of people infected develop at least one lingering health problem after 30 days with #COVID19. The most common included pain, breathing trouble, high cholesterol, malaise and/or fatigue and high blood pressure. 🧵 google.com/amp/s/time.com…
2) But the reported post-COVID symptoms were quite varied, running the gamut from depression and anxiety to skin conditions to heart issues and gastrointestinal distress.
3) most Long COVID symptoms are more commonly reported by women than men.

Health analyzed private health care claim records for nearly 2 million people diagnosed with COVID-19 in 2020. The people in the study ranged in age from babies to the elderly;
Read 12 tweets
15 Jun
BREAKING—CDC now officially declares #DeltaVariant a “variant of concern”—because much more transmissible (50% faster than #B117, 2x than original strain), more severe (2.5x hospitalization risk than B117, 4x original) & 1 dose vaccine evasive.🧵 #COVID19
cdc.gov/coronavirus/20… Image
2) This comes on the heels of the urgent advocacy by many to demand CDC upgrade to VOC. Even WHO and UK 🇬🇧 raised #DeltaVariant to VOC weeks ago. CDC is very late on this.
3) We have known #DeltaVariant has been rising fast in the Us for quite a while. Over a week ago, we already knew it was exponentially rising across the US. It’s doubling every 2 weeks overall, but doubling every week in certain states.
Read 13 tweets
14 Jun
⚠️New CDC warning on rising RSV again. Coincided with dropping of mask mandates & usage. ➡️ “The CDC is issuing this health advisory to notify clinicians and caregivers about increased interseasonal respiratory syncytial virus (RSV) activity across parts of the Southern US.” 🧵
2) CDC: “Due to this increased activity, CDC encourages broader testing for RSV among patients presenting with acute respiratory illness who test negative for SARS-CoV-2, the virus that causes COVID-19. RSV can be associated with severe disease in young children and older adults”
3) “RSV is the most common cause of bronchiolitis and pneumonia in children under one year of age in the United States. Infants, young children, and older adults with chronic medical conditions are at risk of severe disease from RSV infection.
Read 7 tweets
14 Jun
So, vaccines good against hospitalizations, yes, but not when just 1 dose against #DeltaVariant, not when <50% fully vaxxed. Despite new controversial case-control efficacy study (very small & assumption laden)—🇬🇧hospital #COVID19 surges just don’t lie.🧵 assets.publishing.service.gov.uk/government/upl…
2) Note how much weaker 1 dose is versus 2 doses for the #DeltaVariant for both infection and hospitalization.
3) What is the first clue the new controversial study is unreliable? The Pfizer 2 dose results aren’t even significant due to wide 95% CIs. Second, the 1 dose is stronger than 2 dose for Pfizer? Hog wash. We know that’s not true and opposite. This is why this study unreliable.
Read 4 tweets
14 Jun
Masks are coming off—the cold and flu is now back. Coincidence? No. The CDC just issued a health advisory about increased cases of respiratory syncytial virus, or RSV, across parts of the southern US — something CDC hadn’t seen since April 2020. #MaskOn
bostonglobe.com/2021/06/14/met…
2) RSV is a cold-like respiratory illness that produces symptoms similar to COVID, and can cause severe illness in older adults and young children. It disappeared for a year because of #COVID19 mitigations. It’s now back because masks are coming off, especially in the South.
3) Since the state’s mask mandate was lifted at the end of May, face coverings have started to come off — and stay off. But according to infectious diseases doctors, the return of facial freedom might come with some downsides, like a resurgence in cases of the common cold and flu
Read 10 tweets

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