1/ Great question -- and an important one.

The majority of things I'd "take back" have more to do with my having a simplified version of certain concepts that I now much more about (and would present as such)

But I'll be hit up on those things that are more overtly incorrect...
2/ Probably the biggest is my originally saying "Low Density Lipoprotein's primary purpose" is to deliver fat for energy. I had meant it at the time as the class opposite HDL (thus, all ApoB). Sure, a few slides later I differentiate with VLDL, IDL, and LDL...
3/ But the more appropriate way to have stated the same thing would have been: "The primary purpose of ApoB-containing lipoproteins overall is to deliver fat-based energy."

However, I don't think I'd like this statement as much either given how ApoB impacts immune other mechs...
4/ Yes, I still think if you alter my original statement to ApoB it would stand up (TG secretion is a primary driver), but I'd prefer now to emphasize the other important roles as well, such as immune response and cell structure support.
5/ Another place I wasn't so much wrong as I didn't think it was as big a magnitude as I do now -> weight loss and lipids. In 2017 I figured it was relevant, but marginal impact. 2021 me would so it's super relevant with likely a big impact, especially where metabolically healthy
6/ A lot of the other things I'm thinking of are either more nuanced or things I thought then and said in private conversations at the time. Little things like size comparisons for total pool of lipoproteins relative to the total volume of blood.
7/ All that said, I'm sure I could come up with some more. These are just what come to mind in this moment.

Note I'm not including straight up misstatements, as those are different. For example, I said "growth hormone" once in an interview when I meant to say "growth factor"

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More from @DaveKeto

13 Jun
1/ #ListeningThread — actually didn’t know this, but @BioLayne has a podcast. I actually found it in reverse as I’ve been hunting down all things Hypertrophy - and they have a recent podcast with @YngvaiMalmsteve on the topic so I’ll give it a listen… open.spotify.com/episode/2tgWUE…
2/ @BioLayne “… if you torture the data enough, you can get it to show what you would like it to show.”

This is actually a variation I was one of my favorite quotes of all time.👇
3/ it’s also very prescient in its timing. I was actually just talking with @NutritionMadeS3 yesterday, and why I tend to be more interested in studies that work off open or shared data sets given the level of transparency in the statistical instruments being used…
Read 6 tweets
7 Jun
1/ Interesting thread via @ck_eternity_

I'll add some thoughts in my own thread to follow, but consider reading his entirely first.

As always, this is in the spirit of discourse. Love keeping it respectful and productive on such challenging topic. :)
2/ Before getting started, note the coming #LMHRstudy will effectively be tackling much of these common considerations quite directly as we study #LMHRs who have considerably high #LDL from being fat-adapted with otherwise #CVD healthy metrics (See CitizenScienceFoundation.org)
3/ While not commonly known, another major carrier protein for chol is Albumin. It's typically considered in light of transporting NEFAs, but its binding sites can (and are) applied to many other lipids, including cholesterol.
ncbi.nlm.nih.gov/pmc/articles/P…
Read 13 tweets
6 Jun
1/ #Keto > #LowCarb

It’s a ironic, my bloodwork looks fine when I’m either keto (less than 25 net carbs) or low carb (25-100 net carbs).

I have a lot more choices when I am low-carb and the food experience is generally more pleasurable with more treats and greater variety…
2/ But in all that time outside of when I’m eating, I just typically feel better. More balanced, better focus, and on top of all of that, I find I simply think about food a lot less. While it’s fun to anticipate a good meal, it can also be an unhelpful distraction.
3/ It’s annoying to have to identify food that is satisfying, but not *too* satisfying. Food I can enjoy but won’t actively overeat. That’s pretty much everything super low carb that isn’t highly refined (I could definitely drink way too much heavy whipping cream “fat shakes”)
Read 4 tweets
4 Jun
1/ An aside -- I'm working on a diet protocol of sorts. In a sense, I'm combining a number of techniques I've picked up from my experiments and seeing if it "works" for me. So far, it definitely has been. I'm nearly to the weight I was right before the Weight Gain Experiment
2/ As a little background, I was usually around 185-ish lb before that experiment, then after completing it and going back to keto, I started to average around 195 (I'm 6'3, btw, so BMI would be 24.4 at that level)
3/ I've chatted about this many times on the MMM (our member stream) with @siobhan_huggins, and have wondered if this was simply a new set point of sorts. Maybe it's the added stress, long hours, and not-so-great sleep schedule.
Read 9 tweets
1 Jun
1/4 Talk about timing.

My wife follows @naomiosaka and is a big fan. This all happened to take place in the last few days right at the end of #MentalHealthAwarenessMonth

I know it's a common assumption celebrities and athletes enjoy fame and love to talk to the cameras...
2/4 ... But this assumption also makes it that much harder for those who struggle with public anxiety to be open about their hardships.

Many consider Naomi to be the best in female tennis, which is why this has real potential to put a new spotlight on this challenge.
3/4 ... To be sure, I don't think it's as simple as allowing athletes to pass on any press of any kind in an international sport. But I do think it's possible this ultimately leads to policy changes that can be more accommodating to many like Naomi.
Read 4 tweets
28 May
#OpenThread - Friday Musings...

Long before streaming existed I dreamt of the wonderful day I wouldn’t have to physically get media (like VHS or DVD) to play it. But now that we’re here, do I miss the joy of owning, the cover art, the collecting?

Nope. Not even a little.
... I’m definitely an MCU fan boy, but I continue to be incredibly impressed at the whole story behind the campaign to make #ZackSnyder’s Justice League cut for @hbomax a reality and the persistent campaign to #restorethesynderverse. Seems like anything is possible now.
I love cheese.

and I make no apologies for this love

it is a True Love – one that will never die
Read 9 tweets

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