Thread by @DaveKeto

1/ Great question -- and an important one.

The majority of things I'd "take back" have more to do with my having a simplified version of certain concepts that I now much more about (and would present as such)

But I'll be hit up on those things that are more overtly incorrect...

https://twitter.com/Statins_Kill/status/1403793884895928322

2/ Probably the biggest is my originally saying "Low Density Lipoprotein's primary purpose" is to deliver fat for energy. I had meant it at the time as the class opposite HDL (thus, all ApoB). Sure, a few slides later I differentiate with VLDL, IDL, and LDL...

3/ But the more appropriate way to have stated the same thing would have been: "The primary purpose of ApoB-containing lipoproteins overall is to deliver fat-based energy."

However, I don't think I'd like this statement as much either given how ApoB impacts immune other mechs...

4/ Yes, I still think if you alter my original statement to ApoB it would stand up (TG secretion is a primary driver), but I'd prefer now to emphasize the other important roles as well, such as immune response and cell structure support.

5/ Another place I wasn't so much wrong as I didn't think it was as big a magnitude as I do now -> weight loss and lipids. In 2017 I figured it was relevant, but marginal impact. 2021 me would so it's super relevant with likely a big impact, especially where metabolically healthy

6/ A lot of the other things I'm thinking of are either more nuanced or things I thought then and said in private conversations at the time. Little things like size comparisons for total pool of lipoproteins relative to the total volume of blood.

7/ All that said, I'm sure I could come up with some more. These are just what come to mind in this moment.

Note I'm not including straight up misstatements, as those are different. For example, I said "growth hormone" once in an interview when I meant to say "growth factor"