Unless some drug shows up that has better results, any drug will have to be combined with diet and/or exercise to have any significant effect on obesity.
But then we've come full circle: diet is the most effective anti-obesity intervention.
2 problems:
1. Health authorities seem unable to say that the modern food supply causes obesity. They talk impotently about "calories" instead.
2. Drugs are just a way to let people get minor weight loss while not changing their diet.
One can sympathize: most people are not going to change their diet significantly.
Yet the answer is obvious: eating low-carb real whole foods.
Until health authorities say this, and people change accordingly, obesity as a public health problem remains intractable.
As an individual, you can change.
But if we expect obesity as a wider phenomenon to go away, I'm afraid we'll be waiting a long time.
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For those of you who don't know, NAC and glycine are cheap OTC supplements.
NAC is a delivery vehicle for the sulfur amino acid cysteine, which oxidizes readily but does not when formulated as NAC. Cells take up NAC and convert it into cysteine.
Glycine is itself an amino acid
The results of this study show that the combination of NAC and glycine in people age 71-80 fights aging, and the results are not weak.
Since the supplements used are amino acids, that means that someone eating a higher protein diet might get similar results.
My client Majed completely transformed his body composition in just 12 weeks: down 20 pounds and 4 inches around his waist.
Here’s his testimonial:
“I had a big belly even though I was working out 4-5 days/week
Truth is, I wasn’t sure that coaching would work
But clearly, PD’s advice was spot on
I went from 4-5 days a week training, to only 2 days a week
And I lost 4 inches off my waistline, my arms are bigger
And energy levels are fantastic"
If you want an effective, efficient and, most importantly, SUSTAINABLE strategy designed just for you
So that you can
-Lose the excess body fat once and for all
-Get all the health benefits of exercise in 40-50 minutes per week
-Have the freedom to NEVER go hungry
N-acetylcysteine is a safe, effective, and cheap OTC supplement that's been shown useful in many different health conditions.
That's why the FDA doesn't want you to have it.
Here's an example of why n-acetylcysteine irks the establishment:
N-acetylcysteine reduces disease activity by blocking mammalian target of rapamycin in T cells from systemic lupus erythematosus patients
RCT
Authors specifically mention how cheap NAC is:
"A monthly supply of 600-mg NAC capsules... costs $15–30 on the retail market... sharply contrasts with the estimated average annual direct medical costs of ∼$22,580 per patient in 2009. Thus, the cost of NAC at $180–360/year would be negligible" compared to lupus burden.
When untrained men trained for 6 weeks, VO2max and peak cardiac output increased, but the increase was abolished by calibrated phlebotomy to bring their blood volume back to baseline.