Yes, the vaccines ARE effective against the Delta variant. Yes, you will need both doses for maximum protection. Yes, they’re effective against preventing symptomatic infection, severe disease, AND hospitalization. Several studies have proven this now. Stop the misinformation.
Regarding the concerns about waning immunity. Please remember, this is likely referring to infection (see my most recent post on University of Pennsylvania’s study). Not effectiveness against symptomatic infection, not effectiveness against severe illness.
While neutralizing antibodies decrease over time (as they ARE supposed to) protective immunity provided by memory B-cells and T-cells is STILL present.
The term infection refers to the virus entering and being detectable in your system regardless of whether OR NOT it makes you sick, whereas the term illness refers to the virus entering, being detectable in your system AND making you sick. It it important not to conflate the two.
The first thing to know about the COVID-19 vaccines is that they’re doing exactly what they were designed and authorized to do. Since the vaccines first started their rollout late last year, rates of COVID-19 disease have taken an unprecedented plunge among the immunized.
The second thing to know about the COVID-19 vaccines is that they’re flame retardants, not impenetrable firewalls, when it comes to the coronavirus. Some vaccinated people are still getting infected, and a small subset of these individuals is still getting sick
-and this is completely expected. Read here: theatlantic.com/science/archiv…
Your Vaccinated Immune System Is Ready for Breakthroughs. Getting COVID-19 when you’re vaccinated isn’t the same as getting COVID-19 when you’re unvaccinated. Want to know why? Read here: theatlantic.com/science/archiv…
A study out of the University of Edinburgh shows that vaccine efficacy against severe COVID-19 has NOT significantly decreased since Delta became the predominant variant, is around 92%, and does NOT differ significantly between AstraZeneca, Pfizer, and Moderna’s vaccines.🧵
In addition, efficacy against the broader category of hospitalized or fatal COVID-19 remains only SLIGHTLY lower for AstraZeneca’s vaccine than for the mRNA (Pfizer and Moderna) vaccines (88% versus 91%).
NOTE: The REACT-SCOT case-control study data extracted here INCLUDES cases presenting up to September 2nd, 2021, however the analyses reported here are restricted to cases and controls presenting FROM December 1st 2020 to August 19th 2021 (8 MONTHS).
Delta is currently the most prevalent variant in Germany.
For those 60 and older:
•Against Infection: 83%
•Against Hospitalization: 94%
•Against ICU Admission: 94%
•Against Death: 91%
Germany uses Pfizer, Moderna, AstraZeneca, and Johnson & Johnson COVID-19 vaccines. The vaccines are highly effective in preventing severe disease, hospitalization, and death due to COVID-19 even in the face of the Delta variant.
Just HOW effective are the COVID-19 vaccines at protecting you from severe illness and hospitalization even in the face of Delta?
BEFORE Delta variant increase: 95% effective
DURING Delta variant increase: 92% effective
Answer: VERY EFFECTIVE
Let’s discuss. 🧵
Real-world data out of King County, WA (which includes Seattle) confirms vaccinated individuals are significantly better protected from illness, hospitalization, AND death due to COVID-19 compared to unvaccinated individuals, even as the Delta variant surges through the state.
Over the PAST 30 days, unvaccinated individuals were:
•7X more likely to test positive for COVID-19 (69% of cases)
•49X more likely to be hospitalized for COVID-19 (87% of hospitalizations)
•32X more likely to die of COVID-19 related illness (72% of deaths)
A study out of the University of Illinois shows vaccinated individuals with a “breakthrough” infection are LESS likely to shed infectious virus at a given viral load, shed for a SHORTER period of time compared to unvaccinated individuals, AND report fewer days of symptoms.🧵
To shed light on how vaccine breakthrough infections compared with infections in immunologically naive individuals, researchers examined viral dynamics and infectious virus shedding through daily longitudinal sampling in a small cohort of adults infected with
SARS-CoV-2 at varying stages of vaccination (in this case mRNA & J&J). The durations of both infectious virus shedding and symptoms were significantly reduced in vaccinated individuals compared with unvaccinated individuals. Researchers also observed that breakthrough infections
Peer-reviewed. 1M+ sample size. A UK study on “breakthrough” infections shows individuals who tested positive for SARS-CoV-2 after 1 OR 2 doses of a vaccine had significantly LOWER odds of severe disease, hospitalization, OR developing Long COVID than unvaccinated individuals.🧵
Researchers found that the odds of having symptoms for 28 days or more after post-vaccination infection were approximately HALVED by having two doses of a vaccine. Their results suggest that the risk of Long COVID is reduced in individuals who are fully vaccinated, when
additionally considering the already documented REDUCED risk of infection overall. Vaccination (compared with no vaccination) was associated with reduced odds of hospitalization or having more than five symptoms in the first week of illness following the first or second dose,