Weekend Digest
Name the pathogen
5 Clues
#Lymphocytosis
#Macrolide
Posttussive #vomiting
Respiratory #droplet
#VaccinesWork
Name the pathogen
5 Clues
#Lymphocytosis
#Macrolide
Posttussive #vomiting
Respiratory #droplet
#VaccinesWork
2/
#Bordetella pertussis
Fastidious gram-negative coccobacillus
Transmit: respiratory droplets - highest transmission during the catarrhal stage
#Bordetella pertussis
Fastidious gram-negative coccobacillus
Transmit: respiratory droplets - highest transmission during the catarrhal stage
3/
#Bordetella pertussis
#Pertussis is a clinical diagnosis
Stages
1. catarrhal stage: similar to URI with mild cough and coryza
2. paroxysmal phase: classic s/s with cough paroxysms, an inspiratory whoop, and posttussive vomiting
3. convalescent stage: cough subsides
#Bordetella pertussis
#Pertussis is a clinical diagnosis
Stages
1. catarrhal stage: similar to URI with mild cough and coryza
2. paroxysmal phase: classic s/s with cough paroxysms, an inspiratory whoop, and posttussive vomiting
3. convalescent stage: cough subsides
4/
#Bordetella #pertussis
Pertussis is a clinical diagnosis.
Leukocytosis with #lymphocytosis is a classic non-specific laboratory finding
Microbiologic test for confirmation: culture, PCR, serology
#Bordetella #pertussis
Pertussis is a clinical diagnosis.
Leukocytosis with #lymphocytosis is a classic non-specific laboratory finding
Microbiologic test for confirmation: culture, PCR, serology
5/
#Bordetella #pertussis
Treatment of choice: macrolide azithromycin or clarithromycin
Alternate: TMP-SMX
Prevention:
1. Vaccine
2. Post-exposure prophylaxis (regardless of vaccine status)
#Bordetella #pertussis
Treatment of choice: macrolide azithromycin or clarithromycin
Alternate: TMP-SMX
Prevention:
1. Vaccine
2. Post-exposure prophylaxis (regardless of vaccine status)
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