🧵 1/ I really like the idea of “test to stay” in US K12 schools

There are actually several different policies called this, but a big one is testing to reduce K12 quarantines when a person/group is a close contact of positive case. I think that’s a great use of “test to stay”
2/ One confusion I see in comments on Dr. Mina’s post is people thinking of very sensitive PCR testing, which can pick up infections in days when people are no longer contagious

“Test-to-stay” typically uses Rapid Antigen Testing: RAT finds those who are actively contagious
3/ One drawback is there will be occasional false positives with widespread use of rapid antigen tests. So a fast, easy protocol for additional testing to confirm (or refute) positives needs to be in place
4/ My kid’s elementary school does not have a test-to-stay program but has universal masking & follows CDC guidelines that others don’t have to quarantine if following the school’s masking, eating guidelines (school also has HEPA cleaners in every class, etc)
5/ I know this quarantine policy made some other parents in our COVID-conscious district nervous, but I think it’s working out well so far

Our school has had some cases but very few people considered “close contacts” who had to quarantine. No outbreaks
6/ A practical reason I like our elementary school’s universal masking policy is not having to worry about my kid being quarantined

(I know an alternative is getting rid of masking *and* quarantines, but not my preference: ending up with an outbreak not preferable to me)
7/ We do have once-a-week rapid antigen testing at school funded by our state’s department of health but it’s opt-in

Last I heard, only about 35% of kids’ parents had signed them up (including yours truly! 😁)

We get a text every Friday with the results: negative so far!
8/ There is one test-to-stay aspect of the school’s program: if a kid has a runny nose, etc, at school and is opted in to the testing, the school nurse can give them a rapid test. If negative, they won’t have to be sent home
9/ I know less about how that part of the testing is going or how often it’s being used, but I think it’ll be useful this winter.
10/ I’ve said before that I think #COVID19 policy is best when it’s context-specific. What’s working well in one place might be a total fail elsewhere

So here’s my context: COVID-averse, high vax & high-mask community in a lowish vax region. More details👇🏾 in @nytimes map pic Color-coded nytimes map of region surrounding my county, Ora
11/ Also I know I give #NIH a hard time re: funding priorities (still do!), but I wanted to highlight cool projects ongoing through RADx-UP, evaluating different testing schemes in schools. Overall RADx funded by ARA, the 3rd US COVID stimulus bill

nih.gov/news-events/ne…
12/ Here’s list of all the RADx-UP projects. I have quibbles about how program is framed, but each research project looks REALLY interesting!

Big objection: I wish they’d started these in July 2020, not July 2021. We’d have more tested strategies by now nih.gov/research-train…

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More from @WhitneyEpi

29 Sep
1/ I’m SO into this new episode of #SERiousEpi!!

I’m literally talking into air, trying to inject myself into the conversation. I decided better to just tweet my thoughts!

pca.st/episode/cefa36…
2/ Re: p-hacking: I was really lucky to learn about dangers of p-hacking/selective reporting/publication bias early when I took Charlie Poole’s meta-analysis class in my MSPH at @UNCSPHResearch

Seeing the funnel plot assymetry in study estimates was powerful!
3/ We even published this study 👇🏾 years later.

If I’d known how much work it was going to be, I may not have done it! But I was young & energetic & totally in love with Epi Methods 😍…

Same story as everyone!

scholar.google.com/scholar?hl=en&…
Read 7 tweets
28 Sep
🧵1/n Game on! Sounds like FDA process for deciding availability of #CovidVaccines for 5 yo - 12 yo has kicked off

A couple thoughts on how I’m thinking about this decision for my 6 yo…
🧵2/n To my knowledge, my kids haven’t been infected with #SARSCoV2 - but I’ve accepted that they probably will at some point because of where we live (US)
🧵3/n So then my decision is whether I’d like that first infection to be in a naive immune system or in one already primed by vaccination for a quicker immune response
Read 11 tweets
22 Sep
1/ This article does a good job presenting several foundational public health tenets that I’ve felt frustration at not communicating earlier and better:
2/ the big one:

A disease that hurts a small % of a huge population can hurt a LOT of people

Small increases in risk for a person can seem relatively inconsequential but still have big, longterm effects on a large group of people Screenshot of a paragraph of The Atlantic article that is li
3/ It’s a mind-bending way of thinking that I see people grappling w in real time re: COVID

That self-learning is cool to watch from a teaching & learning perspective but scary when critical decision-making depends on understanding the implications of this seeming contradiction
Read 12 tweets
28 Aug
🧵1/10 Whew! I felt this article deep in my soul…
🧵2/10 This quote from @oni_blackstock (starts with “In our community…”) especially hit powerfully. I’ve rarely felt my experience of the pandemic articulated with such precision. bit.ly/3DikPP3
🧵3/10 Scholars like @JessicaCalarco have done beautiful work describing the key role that US women play as “family health managers” and how the pressure of that role has often translated into vaccine skepticism, etc, especially among White politically conservative women in US
Read 10 tweets
21 Jul
🧵 1/ In Feb 2021, well-conducted national serosurvey found ~25% of India had #SARSCoV2 antibodies

Didn’t stop Twitter “experts” from concluding India was at herd immunity & should be fully opened

High ranking & everyday people alike bought into this fiction…
🧵2/

These scientific-sounding lies lowered rates of vaccine uptake & NPI. After all, prominent people said everyone already had protection from infection & cross-reactivity w other viruses

These people were extremely wrong bbc.com/news/world-asi…
🧵 3/ In India & the rest of South Asia now, we see that words matter, that scientific-sounding distortions of reality matter

I remain enraged & heart-broken bc that scale of outbreak absolutely didn’t have to happen in a vaccine-exporting & scientifically rich country in 2021
Read 7 tweets
22 Jun
1/ Good overview of challenges of doing “big data” health care research in US. For instance, nice description of basic pros and cons of insurance claims vs #EHR health care records

HT @ABatemanHousetechnologyreview.com/2021/06/21/102…
2/ But the article has a prematurely triumphant tone at the beginning (and in the default Twitter tagline). N3C is great but limited, as the article does make clear
3/ And it’s not totally novel. But the novelty to me is that it’s

a non-“federated”* model

*not* run by for-profit companies,

so the data are accessible to the public for analysis

*this term is explained in article
Read 6 tweets

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