A thread on the Delta AY.4.2 in South Africa. AY.4.2 has been detected in very small numbers in SA. No current cause for alarm – continued surveillance and monitoring important. Tweet 1/6 
In total 6 of 9,017, Delta genomes in SA are the sub-lineage AY.4.2 (PANGO analysis as of today). No sign of growth and the current COVID-19 cases in SA. On the opposite, infections in SA are current low, and the positivity rate is also very low. Tweet 2/6
These six genomes have been found in 5 provinces and no cluster of infections of AY.4.2 - Tweet 3/6
The main Delta sub-lineages in SA are AY.32 and AY.4 (without the extra mutations of AY.4.2). Tweet 4/6
Conclusions I:
- AY.4.2 has been detected in very small numbers in SA
- Delta is dominant in SA and throughout the world - further evolution of delta is expected where transmission is not controlled Tweet 5/6
- AY.4.2 has been detected in very small numbers in SA
- Delta is dominant in SA and throughout the world - further evolution of delta is expected where transmission is not controlled Tweet 5/6
Conclusions II:
- AY.4.2 is expanding across the UK but not yet clear whether it has an intrinsic growth advantage - more genomic analysis and phenotypic assessment needed.
- No current cause for alarm – continued surveillance and monitoring important. Tweet 6/6
- AY.4.2 is expanding across the UK but not yet clear whether it has an intrinsic growth advantage - more genomic analysis and phenotypic assessment needed.
- No current cause for alarm – continued surveillance and monitoring important. Tweet 6/6
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