#LongCovid and sleep disruption.πŸ’€πŸ› 🧡
An area to address with urgency, both in terms of quality of life and as evidence of deeper health issues.
A percentage of patients may reveal sleep patterns indicative of long term neurodegenerative disease, a new study reveals πŸ”½
For the sleep study in question: a small sample (n=11 patients) mostly men (n=9 patients)
To note: relatively young age (52 years +/- 11 years)
Based on a follow up 60 days after covid diagnosis
64% of patients presented breathing complications

#LongCovid
#LongCovid patients have been reporting sleep problems for long. Sleep disruption is a documented long term effect of SARS-CoV-2 infection in numerous clinical studies.
Sleep problems are significant clinical issues that have often been poorly addressed in primary care and beyond
Hopefully, new interest into sleep disruption in chronic illnesses, including (post) infection diseases like #MECFS will be sparked by research on covid sequelae
Sleep problems are issues with great impact on life quality and may be first evidence of severe disease

#LongCovid

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More from @elisaperego78

29 Oct
I'm disappointed by this statement from a number of medical associations in the UK in response to the @NICEComms publication of the new #MECFS guidelines

I've concerns, in particular, about the view of chronic diseases reflected in the statement 🧡

rcplondon.ac.uk/news/medical-l…
A first concern regards the full scope of clinical guidelines for a severe (post) infection disease like #MECFS: growing research on viral/other onset diseases reveals a multi-system, complex pathophysiology
You can't cure this with exercise or psychological therapy (CBT)
We really need the full extent of biomedical research on viral-onset and related diseases to be taken into consideration. Patients need appropriate treatment and support, not poor quality intervention that don't address a complex pathophysiology with severe symptoms

#MECFS
Read 7 tweets
15 Oct
Important summary of covid pathology in the lung from newly published tissue biopsies.
Note the truly astounding devastation from SARS-CoV-2 in fatal disease, including clotting.
I add a few points on how paper can be relevant to #LongCovid and non-critical patients 🧡
πŸ‘‰ covid pneumonia can be asymptomatic/ pauci-symptomatic e.g. paper attached πŸ”½
πŸ”₯ phenomena as those found in critical patients, but on a lesser scale, can thus affect non-hospitalized/ "mild" patients . Long term lung damage can be there

#LongCovid

pubmed.ncbi.nlm.nih.gov/32216718/
πŸ‘‰ imaging techniques like the SPECT scan *do* reveal long term lung damage in #LongCovid πŸ”½
πŸ”₯ in view of potential, significant lung damage even in "mild" patients, it's key to stop discussing symptoms like breathing difficulty as "anxiety" and the like
pubmed.ncbi.nlm.nih.gov/34339624/
Read 5 tweets
13 Oct
In the wake of increasing recognition of failed pandemic responses worldwide, like in the UK

Let's always remember that many early covid patients from Wuhan weren't "old and sick"

This was already clear from January 2020 data in @TheLancet

#LongCovid

thelancet.com/journals/lance…
This evidence of early known clinical evidence from Wuhan is especially damning for ideologies like the Great Barrington Declaration, which posited, erroneously, that SARS-CoV-2 infection is not that dangerous in the young. This was already patently not the case in January 2020
#LongCovid and #LongCovidKids are the nail in the coffin of public health "measures" and ideologies that encouraged to let SARS-CoV-2 rip through the population.
SARS-CoV-2 is virus with high mortality, but an even more egregious morbidity rate i.e. long term damage
Read 4 tweets
13 Oct
In our review of #LongCovid rise, @felicitycallard and I noted how forms like "so called" LC were being dropped in mid-2020.
This was because of recognition of the obvious nature of SARS-CoV-2 sequelae
Using "so called" again now, is a political choice to minimize the disease
The re-introduction of forms like "so called" #LongCovid or "Long Covid" is, interestingly, linked to a specific historical phase in the pandemic: the moment in which there is a huge push for "endemic covid" by most policy makers, with no appropriate reasoning about mitigation
The only way the public will swallow the reality of being infected multiple times with a virus likely to give many a disability or increased risk for, for example, cardiovascular disease, is to lie, or muddle the water, about the gravity of SARS-CoV-2 infection
#LongCovid
Read 5 tweets
12 Oct
Excellent points by @ahandvanish @ClaireHastie1 et al. in 🧡
I see public health experts talking nonchalantly about SARS-CoV-2 infection. Some talking about reinfection as an "immune booster".
No.
We don't have any data to make safe predictions.
"Endemic covid" is a bad gamble.
The dangers of reinfection, or symptomatic infection after vaccination, are a special danger to those with #LongCovid and those from marginalised communities, who might not have access to optimal care. But *everyone* can be in danger. Covid is Russian roulette
We literally have no evidence to say multiple SARS-CoV-2 infections across a life will be a minor issue, or a positive, for most! On the contrary, emerging data e.g. from the #LongCovid community, are concerning and warrant extreme caution
SARS-CoV-2 is a very dangerous virus
Read 4 tweets
7 Oct
As an umbrella, #LongCovid refers to the long-term symptoms and sequelae of SARS-CoV-2 infection🧡
You can have delayed pulmonary embolism for sure! We perfectly know cardiovascular and clotting sequelae are key factors in Long Covid, often protracted from the acute phase
It's *crucial*, in my opinion, not to confuse the clinical definition of post-covid condition by the @WHO, or the name PASC, or other non-patient made term with #LongCovid. They aren't synonyms. Long Covid focuses on the long-term disease process from infection onwards
#LongCovid is a sophisticated patient made term. It came into being collectively, via the shared experiences of thousands of people, many of whom are scientists and healthcare professionals. It accounts for both disease development across time and sequelae from acute organ damage
Read 7 tweets

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