1/ this one minute clip was released by @chadinabhan an hour ago, and when I watched it I got a bit concerned that it takes a clip out of context and DMed Chadi about it.
He rightly pointed out my reaction was misplaced as this was strictly a teaser.
2/ However, this did provide me an opportunity to expand on the point, given I understand where @ethanjweiss would feel this was “meaningful”.
In our exchange from several months ago (too lazy to link), Ethan pressed as to whether I’d take a statin post heart attack…
3/ I said then (and I’ll say today) – I don’t know, but I feel it would be irresponsible for me to say one way or another.
But what came up in this podcast, is it would be meaningful to Ethan if I pointed out that post MI-research I’d see a scenario where I would.
4/ In other words, should someone take my “I don’t know, I’d need to research were that to happen”
as a
“I’m pretty sure I’d never take a statin, I don’t see any scenario where I would.” 👈 no! This is definitely not my position.
5/ I would research the data, look at it vs the context I was in, and all options would be on the table. It’s quite possible that I would conclude it would be appropriate for me to take a statin (and/or other Rx). But I don’t know. (Again, it would depend on the context emerging)
6/ I went ahead and also did a seven minute video on this for Instagram…
1/ I want to take a moment to have a back-and-forth exchange with @MichaelMindrum in a thread, and I’m just gonna keep it to us (Tweet setting) I’m confident we can keep it productive. 👍
First, I think we should get on the same page with where I’m coming from..
2/ I’m not just interested in high LDL for LMHRs. I’m interested in whether it’s meaningful to distinguish high LDL from what appears to be lipid metabolic dysregulation versus high LDL in the context of metabolic fat adaptation.
3/ Much of those following this account know this already from following my work, but often critics do not.
That’s why I’d love to specificity talk to a critic I like, such as yourself, and really unpack this so we can better narrow down where the real disagreements are.
As many of you know, we're conducting a study on #LMHRs (link later in thread) who not only have extremely high #LDL#Cholesterol, but many (likely most) have diets quite contrary to this advice by the @American_Heart.
2/ First, and most importantly, we do not know what the outcome of this prospective study is. So while I'll be outlining commonalities we observe with #LMHRs, this isn't an explicit endorsement of the diet nor any altered lipid levels as a result.
With that said...
3/ We have a lot of data between our standing survey, submissions to CholesterolCode.com, and CC and LMHR Facebook groups (7.7k and 7.5k members, respectively).
Diets are often: 1) Low to no fruits & veg 2) Low to no grains 3) High animal protein 4) Low in plant oils
I now suspect #PlantBasedLowCarb (PBLC) isn't as low carb as originally thought.
Before getting started in this thread, I should emphasize I wouldn't consider this a good or bad thing in and of itself, but it is of interest, ofc...
2/ Moreover, I've regularly pointed to people following my work who are both (1) very interested in a low carb diet, but (2) would prefer to keep their #LDL low to consider PBLC as a "third option", as I commonly see it associates with this outcome.
Now to my hypothesis...
3/ PBLC generally has two major features separating it from "typical" #keto/#lchf:
1) More fat sourced from mono and polyunsaturated fatty acids (M/PUFA) instead of saturated fatty acids (SFA)
2) A lot more soluble and insoluble fiber via plants
2/ Imagine a room full of people at tables being served with trays of food regularly coming from the kitchen moved around the room by waiters.
No one is particularly famished, but they aren't especially full either, so they are absently taking food off the trays to maintain...
3/ However, a few guests at one table leave to get some exercise and return quit hungry.
And here's the catch: You can't tell specific people to do specific things (including the waiters), but you can say things to the entire room. Is there a way to solve this puzzle?