"Ireland is home to one of Europe's highest vaccination rates...three-quarters of all people, having been immunized -- but it recently imposed a midnight curfew ...as it battles a growing surge in cases and hospitalizations"
1/9

edition.cnn.com/2021/11/19/eur…
"...even small pockets of unvaccinated people can drive transmission...Ireland...around a million are still not protected.
"...we have...an epidemic of the unvaccinated -- about 10% of our population over 12 is unvaccinated, and we're seeing an epidemic in those people..."
2/9
"...elderly and vulnerable people with co-morbidities can still suffer breakthrough cases, and asymptomatic, healthy people are catching and passing on the virus.
"The combination of those four or five things has meant that our hospitals are getting quite full""
3/9
"...difference between vaccination rates of 70% and 80% is huge...because each extra percentile further isolates the virus and eases pressure on hospitals."
4/9
"...no country can truly consider themselves "highly vaccinated"...until they inoculate a percentage in the mid-90s of their total population, unvaccinated pockets of society would still drive transmission."
5/9
"Spain...Portugal...vaccination...80% and 87% of the total population...have seen uptake...and have also relaxed rules...in recent months. But so far, they have avoided the worst of the current wave -- with experts pointing to the apparent success of their mitigation measures.
6/
"...use of masks is only compulsory indoors, and this is generally accomplished...Despite achieving high rates of vaccination...moved slowly and cautiously towards normality -- as well as in indoor public spaces, masks are still required on public transport..."
7/9
"the difference in vaccination coverage in different countries is making the big difference in incidence rates,"...(But) it's not the only explanation
8/9
"...in countries where vaccination rollouts have stalled...Germany...Within a short period of time it's not possible to achieve vaccination rates that would stop this wave,...following measures and reducing socialization can make the immediate difference."
9/9

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More from @Friedemann1

24 Nov
Warum sind unsere Impfquoten nicht ausreichend? Ich denke viele der Mythen, welche die Leute verunsichert haben, gehen auf den Flyer zurück, der Anfang 2021 in die Briefkästen geworfen wurde. Verantwortlich dafür sind @SHomburg und Sucharit Bhakdi
1/
Schon das Deckblatt nutzt den klassischen "ich stelle doch nur Fragen"-Trick.
Und die abgebildete Spritze, naja, die Größenrelation zu dem niedlichen Teddybär entspricht nicht direkt der Realität beim Impfen (man beachte auch: blutiges Pflaster, umgekippte Impfampulle)
2/
Los geht's mit dem Text:
Was unterschlagen wird:

Impfung: ist nur 1 Virusgen ("VirusgenE" ist also falsch)
Infektion: mindestens 10 verschiedene Virusgene
3/
Read 13 tweets
21 Nov
Was haben denn Impfungen je für uns getan? Unglaublich viel!

Leider verschwinden die Erfolge dieser erfolgreichsten aller medizinischen Maßnahmen nur allzu schnell aus dem kollektiven Bewusstsein, und man nimmt die Abwesenheit fieser Keime als gegeben an

1/n
Wichtiges Beispiel: Pocken, eine sprichwörtliche Geisel der Menschheit.

Hier eine Beschreibung des Todes von Ludwig XV, der sich bei einem Schäferstündchen das Virus eingefangen hatte. 10 Tage später das da:

2/n
Dies und vieles was folgt sind aus:
(Sehr empfehlenswertes Buch, ca.1200 spannende Seiten plus weitere 500 Seiten Referenzen. Ich gebe 10 von 5 Sternen)

3/n

penguinrandomhouse.de/Buch/Die-Gesch…
Read 19 tweets
10 Nov
I have a totally unproven hypothesis why the australian society did not discuss much before they imposed fast and robust public health measures against SARS-CoV-2: They already had quite some bad experiences with invasive species

(Thread ends with a kid's TV series!)

1/11
Cane toads: introduced into Australia with the aim to control beetles that were destroying the sugar cane harvest (didn't work)

2/11
nma.gov.au/defining-momen….
Cane toads (dt.: Aga Kröte) soon became a problem themselves. They are prolific eaters (not only sugar cane beetles) and their skin secretes a toxin. Not good for the local ecosystems

3/11
Read 11 tweets
8 Nov
Das ist genau der Punkt: vorspiegeln, man hätte Ahnung.
Und deswegen finde ich es so wichtig, die Trickkiste von Zacki & Co offen zu legen

1/10

Zur Unterstreichung der vermeintlichen Kompetenz verweist man kennerhaft auf Lehrbücher
2/10 Image
Ja, man hat sogar in vielen, eigentlich allen gesucht und gefunden. Nur der Titel wenigsten eines dieser Bücher, auf den warte ich vergebens
3/10 Image
Read 10 tweets
26 Oct
Tot- vs Lebendimpfstoff, was ist das eigentlich und in welche Kategorie gehören die mRNAs?

Wie so vieles hat diese Unterscheidung Tot- vs. Lebendvakzine historische Wurzeln.
1/13
Der Pockenimpfstoff von Edward Jenner (Ende 18. Jh.) bestand aus "lebenden" Kuhpockenviren - diese lösten nicht die gefürchteten Pocken aus, waren aber nahe genug verwandt, um eine schützende Immunantwort zu induzieren
2/13
Ähnlich besteht z.B. der Masernimpfstoff aus abgeschwächten ("attenuierten") Masernviren, die so mutiert sind, dass sie zwar noch Zellen infizieren und sich weiter vermehren können, aber zu schwach sind um sich im Körper zu verbreiten (ausser bei Immundefizienz)
4/13
Read 12 tweets
6 Oct
The season of common cold viruses has started. Due to a phenomenon called "interference", this COULD actually be helping a bit against SARS-CoV-2.
But interference is short-lived, so it is neither an argument to drop the mask mandates, nor to refrain from getting vaccinated
1/10
So what is interference? It means that infection by one virus can be inhibitory to other viruses (either same or different species) that come a bit afterwards. This can be observed both in cell culture and in epidemiology
2/10
The molecular mechanisms behind it can be different, but the most important factor is (drum roll....)

Interferon

Thats where the name comes from (classic paper!)

3/10
acsjournals.onlinelibrary.wiley.com/doi/abs/10.332…
Read 10 tweets

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