Share this page!

Dr Emma Hodcroft Profile picture
Twitter logo
28 Nov, 4 tweets, 3 min read
✨New CoVariants.org @nextstrain focal build for (21K) Omicron now up✨
nextstrain.org/groups/neherla…

This includes all 125 sequences that were available on GISAID this morning.

1/4
We can take a closer look at the cluster and see where sequences have been generated around the world - so far, from South Africa, Botswana, Hong Kong, Israel, Australia, Italy, & Belgium.

2/4
nextstrain.org/groups/neherla…
We need to interpret the genetic diversity of the Omicron cluster with caution - some sequences are better quality than others, which can lead to artefacts. Example, here Australian & Italy sequences are ancestral - erroneous & likely because of missing seq data!

3/4
As with everything else about Omicron, this is a fast-moving & constantly evolving analysis - interpret everything with caution.
Things are also moving slowly in getting large data pulls - updates on CoVariants.org & to the focal build will come as fast as possible!

4/4

• • •

Missing some Tweet in this thread? You can try to force a refresh
　

Keep Current with Dr Emma Hodcroft

Dr Emma Hodcroft Profile picture

Stay in touch and get notified when new unrolls are available from this author!

Read all threads

This Thread may be Removed Anytime!

PDF

Twitter may remove this content at anytime! Save it as PDF for later use!

Try unrolling a thread yourself!

how to unroll video
  1. Follow @ThreadReaderApp to mention us!

  2. From a Twitter thread mention us with a keyword "unroll"
@threadreaderapp unroll

Practice here first or read more on our help page!

More from @firefoxx66

Dr Emma Hodcroft Profile picture
26 Nov
✨CoVariants.org Now Updated✨
B.1.1.529 is designed @nextstrain clade 21K & is now included on covariants.org/variants/21K

Note that data is still incoming! I currently only have the first sequences detected & will update as soon as I have additional sequences.

1/4
The 21K (B.1.1.529) page offers some information about some of the observed mutations - but I'd welcome contributions to link to more research!

On the right you can see the defining mutations - note that nonsynonymous mutations aren't yet available - I'll add them soon.

2/4
You can also see 21K (B.1.1.529) on the Shared Mutations page (& too big to screenshot!) to compare what Spike mutations we also see in other variants.

covariants.org/shared-mutatio…

3/4
Read 5 tweets
Dr Emma Hodcroft Profile picture
25 Nov
Lots of headlines about B.1.1.529 today.

Thoughts: Yes, this variant has a high # of spike mutations, & a few known to cause changes. But, we've seen previous variants that looked worrying & never took off. We should watch & wait for more data to estimate how concerning this is.
As a catch-up for those who haven't seen said headlines, I think this @guardian article on it gives a fair summary, with some level-headed quotes from scientists.
theguardian.com/world/2021/nov…
We got some additional information this afternoon from a press conference with @Tuliodna & @rjlessells. You can watch it below. A brief touch on some of the new information.

Read 12 tweets
Dr Emma Hodcroft Profile picture
9 Nov
"What's the situation in Europe?"
Yes - cases are rising in many places 📈
But it's difficult to talk about 'Europe' 🌍 as one entity right now: as the pandemic continues, things are getting more heterogeneous. 📊

*What one country can manage, may not be true for another*

1/16
First, we have to look both at absolute case numbers & change in case numbers - some places with high cases may see a decrease but remain high 📉, others with lower numbers might be seeing a concerning sharp increase 📈

2/16

ourworldindata.org/covid-cases
Some, like the UK, seem to be dipping up & down around fairly high numbers, making 2-week changes harder to interpret - will there be another bump..?

Others, like Norway, have recent spike, but are at relatively lower cases. Will current spike be contained as before..?

3/16
Read 16 tweets
Dr Emma Hodcroft Profile picture
12 Aug
"Thing is, we have a chance to build office work from the ground up: to re-evaluate the old 9-to-5, to relocate city centre offices, to let people work tight 4-day weeks, to realise that working smart is better than the old-fashioned idea of working hard"

theguardian.com/commentisfree/…
From chatting to people, I think the main reason those high up want people to come back to the office is simple: control.
Even when productivity metrics indicate all is well, bosses don't trust employees & like to be able to physically check on them. Not related to actual output.
I'd be super curious in any survey difference between how much superiors miss "stopping by to chat" vs how much their employees feel similarly.
Read 4 tweets
Dr Emma Hodcroft Profile picture
11 Aug
Headlines like the one circulating about India always need to be taken cautiously: until we have sequence data, speculation about a new variant or new mutations is entirely that - speculation.

But let's dig into what's being reported right now about 40,000 breakthroughs...

1/N
Headlines are saying things like "40,000 breakthrough COVID cases". But what does breakthrough mean here? Most generally, at least in Western media, this is used to refer to infections in fully-vaccinated (commonly 2-dose) people.

2/N
However, 1 site reporting the 40,000 defines this as "people contracting the disease a second time or fully vaccinated".
Another implies this is infection after 1 or 2 doses.

3/N
indiatoday.in/coronavirus-ou…

news18.com/news/india/ker…
Read 7 tweets
Dr Emma Hodcroft Profile picture
28 Jul
Today, my best birthday present is being fully vaccinated! 🎂

But so many still aren't - & the pandemic has wrecked havoc on routine vaccinations too.

Donate to @gavi, @UNICEF or others & I'll match up to $500! Send your receipt to vaccine_donations@protonmail.com & plz RT!

1/
As well as desperately requiring stronger action towards more equitable #COVID19 vaccination, the pandemic has meant so many children weren't able to get basic vaccines.

This could add unnecessarily to the already too-large burden of the pandemic.

2/
who.int/news/item/15-0…
The pandemic has hit a lot of people hard in many ways, including financially. Please do not give if it would cause you hardship. ❤️

There are other ways you can help!
Talk to an unvaccinated friend 🗣️, or put pressure on your government to do more to help globally! 📨

3/
Read 4 tweets

Did Thread Reader help you today?

Support us! We are indie developers!

This site is made by just two indie developers on a laptop doing marketing, support and development! Read more about the story.

Become a Premium Member ($3/month or $30/year) and get exclusive features!

Become Premium

Too expensive? Make a small donation by buying us coffee ($5) or help with server cost ($10)

Donate via Paypal

Thank you for your support!

Follow Us on Twitter!

Like this author's thread?

Get emails when @firefoxx66 has new unrolls!

Check out other threads from @firefoxx66!

Read all threads by @firefoxx66

:(