The #Omicron variant is surging in the US exponentially… CDC data shows that New York / New Jersey region is now over 10% Omicron of all #COVID19 cases. The rest of US is not far behind—likely dominant by Christmas 🎄 — please be careful during holidays.

Figure by @DrWilliamKu.
2) I’m glad that NYC will be distributing free COVID tests and KN95 masks. Thank you @NYCHealthCommr @davechokshi!
3) NYC positivity has doubled in just 2 days. That’s bad bad bad.
4) Cornell University’s #Omicron huge outbreak is not helping NY state’s overall stats. nymag.com/intelligencer/…
5) why is it spreading so fast in NY despite high vaccination? Because #Omicron is highly evasive. See thread 🧵 summary how much it evades 👇

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More from @DrEricDing

17 Dec
⚠️BREAKING—Imperial College study finds #Omicron could be **just as severe** as the Delta strain, according to early findings from researchers at Imperial College London.

➡️All those who said “it’s mild” need to think about how many they have endangered.
ft.com/content/489316… Image
2) “The study finds no evidence of Omicron having lower severity than Delta, judged by either the proportion of people testing positive who report symptoms, or by the proportion of cases seeking hospital care after infection,” said the research team, led by Prof Neil Ferguson
3) Moreover, other London hospitalization data shows it could be sending patients to hospitals a bit faster, even if same severity.
Read 8 tweets
17 Dec
⚠️FASTER HOSPITALIZATION WITH #Omicron—Latest data on hospital admissions in London (🇬🇧Omicron epicenter) shows Omicron wave is sending patients to hospitals sooner in 6 days than versus Delta (9-10 days). And the model suggests similar severity, not “milder”.🧵

Data via @OYCar ImageImageImage
2) Let’s look at the other 10 day model for new #Omicron — it seems it’s a poor fit to the actual hospitalization data. It’s visible on both the log scale and natural scale that it’s not a good fit. ImageImage
3) Now let’s for a moment test whether #Omicron is “milder” - half as severe as Delta, but just sent people to hospital faster, but not as often. Does it fit the data well? Not exactly… the latest few days doesn’t jive with that “milder” model. Image
Read 8 tweets
17 Dec
MASKS ON AIRPLANES—It is “irresponsible & reckless” for @SouthwestAir CEO @gary_kelly & @AmericanAir CEO to question if masks needed. Airplane✈️ transmission proven, #Omicron is much more contagious, & HEPA filters not running on tarmac! Thx @JeromeAdamsMD
2) airplane spread is shown in this key video below 👇
3) and it’s not true that airplanes always have great HEPA cleaning — all the time parked at the gate - usually no HEPA filtration active @AmericanAir @SouthwestAir!!!
Read 5 tweets
15 Dec
📍The coronavirus is airborne. Very airborne. Even if you don’t see anyone—doesn’t mean the aerosols aren’t in the air. WATCH📺

➡️ you need high quality N95 / KN95 / KF94 / FFP2/ FFP3 masks.

➡️ also please ventilate, get HEPA filters, get upper room UV.
2) VENTILATION is key. Both ventilation and masks needed to reduce risk indoors. But most buildings not ventilated well enough.

3) AEROSOLS ARE AIRBORNE.

“Until we recognise that #COVID19 is airborne we are setting ourselves up for repeated failure”
Read 9 tweets
15 Dec
💡New VACCINE RANKING of ability to neutralize #Omicron—Moderna appears to be the strongest against Omicron in this study, but still big drop. Pfizer next best (but we know infection efficacy is 30-34%), AstraZeneca & Sinopharm poor. J&J & Sputnik = zero.🧵biorxiv.org/content/10.110…
2) Natural infection immunity is on the left … “convalescent” = practically no neutralization against #Omicron in this study by itself without vaccine.
3) Meanwhile for SinoVac —one of the world’s most widely used vaccines, doesn’t provide sufficient antibodies to neutralize the #omicron variant, said 🇭🇰 researchers. But a 3rd shot booster seemed up help. bloomberg.com/news/articles/…
Read 13 tweets
15 Dec
NEW—The new #Omicron variant can likely now infect RODENTS 🐁 — the coronavirus couldn’t bind 🐭 ACE2 receptor before… but looks like Omicron can now. I vote for elimination, because I don’t want forever #COVID19 or play whack-a-rat repeated waves of COVID.
2) To be clear, other variants theoretically can bind / infect, but at much lower likelihood. The new study now proves direct binding of Omicron to mouse 🐁 ACE2.
3) notice that other variants only weakly bound mouse 🐁 ACE2. But this study shows #Omicron binding mouse ACE2 is much much stronger than variants (red line in bottom panel), and now binds almost as strong as Omicron binding human ACE2. 👀
Read 5 tweets

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