Maybe these estimates from @IHME_UW will help Canadians understand the severity of our situation.

From Dec 23-Apr 1, Canada can expect 6M-24M COVID infections.

Most likely number: 15 million infections. Most will be unreported.

covid19.healthdata.org/canada?view=in…
@IHME_UW Here's a screenshot of the IHME estimates.

From Dec 23-Apr 1, Canada can expect 6M-24M COVID infections.

Most likely number: 15 million infections. Most will be unreported. Image
Estimated hospital resource use:

Most likely: 1,418 daily hospitalizations, 362 daily ICU admissions, by Feb 24.

Could be as high as 3,269 hospitalizations, 832 ICU admissions, by Feb 13.

Canada's worst day to date: May 9/21: 1,100 hospitalizations, 271 ICU admissions. Image
IHME estimates of new COVID-19 deaths in Canada from now to April 1/22.

Somewhere between 10,000-31,000 deaths.

Somewhere between 3K-15K of these deaths will be reported.

Remember, outside Quebec, only ~half of COVID-19 deaths are reported.

Watch QC closely as we go forward. Image
Finally, if vaccine protection against severe disease has dropped from 90% to 70%, as early South African reports suggest, these future hospitalization and death estimates will be higher.
You'll also note that getting every last person vaccinated, boosted, and ensuring 80% of people wear masks will collectively reduce future severe outcomes significantly.

What's the most important way we can slow spread so that we can get all of this in place?

Social distancing.
I have no idea any more how to explain to people what will happen if we don't modify our behaviour NOW.

Every single person's decisions about this matter. Some of us can NOT socially distance because of work, caregiving, health needs. But MANY of us can.

PLEASE do it NOW.
We need to buy time to ensure new medications are available, to get people vaccinated, boosted, wearing the best masks they can.

If our healthcare workers all get infected too, we are in deep, deep trouble.

Please help us buy time. PLEASE stay home.

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More from @MoriartyLab

26 Dec
Canada, Canadian region estimated FUTURE severe COVID-19 outcomes, as of Dec 17, 2021

🔵Deaths, ICU admissions, hospitalizations
🔵Vaccine-preventable, breakthrough, total

These are numbers estimated if entire population as of July 1, 2021 is exposed.
🧵
docs.google.com/spreadsheets/d…
1. Data sources, methods are at bottom of linked spreadsheet

2. Estimated vaccine-preventable and breakthrough severe outcomes from July 1, 2021 to present have been subtracted from estimated future totals
3. Estimated future deaths, ICU admissions and hospitalizations are based on age-specific OECD rates for the ALPHA strain, which at this point appears likely "milder" than Omicron.

I know many Canadians now think that Omicron is mild. Please see threads about this linked below.
Read 23 tweets
18 Dec
Here's are estimates of severe BREAKTHROUGH COVID-19 outcomes, by age group, in Canada or comparable OECD countries.

Remember, risk of these outcomes are 7-9X higher in UNVACCINATED people.
These are based on the age-specific OECD infection fatality rates for Alpha (so quite conservative), and assume that vaccine protection vs severe outcomes in double-vaxxed people has dropped from 90% to 70% for Omicron, as per recent South African reports.
They're estimates, but remember that Alpha was "milder" than Delta, and that monoclonal antibodies we use for treatment also look like they're taking a big hit with Omicron. These estimates may be revised up/down, but probably not by huge amounts. They're decent ballparks.
Read 54 tweets
18 Dec
Unvaccinated Canadians 40+, I am DESPERATELY worried about you.

1 in 18 of you who get COVID-19 will be hospitalized. 1 in 59 will end up in ICU. 1 in 78 will die.

Nearly 24,000 of you will die before this epidemic ends. 32,000 will end up in ICU. 107,000 will be hospitalized.
You can check your personal risk in your province and health region at the link here.

I beg you. I care about your life--it matters a lot. The people who love you care about you. Please, please, PLEASE protect yourselves.

docs.google.com/spreadsheets/d…
As for doubly vaccinated Canadians 40 and older, especially if your last shot was more than 6 months ago, here are your risks, assuming that vaccine protection from severe outcomes has fallen from 90% to 70% with Omicron.
Read 11 tweets
16 Dec
Omicron may reduce vaccine protection against severe COVID-19 outcomes from 90% to 70%.

If true, this could result in more than 100,000 breakthrough deaths in Canada if everyone is infected.

Get boosted ASAP. Not this weekend. As fast as you can, especially people 40+.
Most of us cannot understand how fast Omicron cases are growing. They will double every 3 days once Omicron is dominant--which will be by the end of this week in Ontario.

Don't just get your booster. IMMEDIATELY start taking precautions to reduce risk of exposure and spread.
And if you're UNVACCINATED, I beseech you--get your first dose immediately. Hospitalizations and deaths will rise exponentially after cases.

If you're 40 and older and unvaccinated, you have a 1 in 17 chance of hospitalization with COVID. You have no time left to wait. PLEASE.
Read 4 tweets
13 Nov
OK. Have finally found age-specific vax rates for Ontario PHUs that more closely resemble national data for ON than those reported provincially.

This really changes our understanding of which Cdn regions are at greatest risk of future deaths, ICU admissions, hospitalizations.
🧵
The most recent age-specific vaccination data from @GovCanHealth indicated the Canadian regions with the highest risk for future ICU admissions, deaths and hospitalizations are, in order, AB, ON, NWT, YK, SK, BC, NB, QC, NS, MB, NL, NUV, PEI.

SK 1st dose vax has really sped up.
@GovCanHealth However, even though ON is now a major concern due to slow vaccination in people 50+, I couldn't figure out how to identify the ON regions at greatest risk because provincially reported vaccination rates are so much higher than national rates, especially in older age groups.
Read 55 tweets
12 Nov
A huge concern that cases are rising so quickly among people 80+.

In Ontario, ~10% of people 80 and older remain completely unvaccinated.

About 1 in 5 unvaxxed people 80+ will die if they contract COVID-19.

ON has one of worst vax rates in the country for people 80+.
More than 17,000 unvaccinated people in Ontario can still die from COVID-19. MANY will be in their 80s.

The HUGE gap in vaccination among people 80+ has been known for MANY, MANY months.

Hang on. I'm pulling out the regional data for vax rates among people 80+ in ON PHUs, together with estimated numbers of deaths that will result when unvaccinated people 80+ are infected with SARS-CoV-2. Not if. When.
Read 24 tweets

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