What can we learn about the 🧠 brain if we map it at a nanometer resolution?

In my latest 🎙️ podcast, I talk to Jeff Litchman (from Harvard University) about their project to map human brain tissue and what insights we get from it.

Listen here ->
1/ They map just 1mm cube of human brain and revealed 1.6 petabytes worth of data, which can fill 3000+ laptop hard drives.

And. 1 mm3 of the human brain which is 0.0001% of the entire brain. The human brain is truly staggering in its richness and complexity and we explore that.
2/ If you want to read the paper with details from the project, here's the link to it biorxiv.org/content/10.110…

In it, you'll find beautiful pictures of the human brain such as this one where one neuron is making several contacts with another.

cc: @harvardbrainsci
3/ The team has released all data and images online.

You can explore the detailed morphology of different cells within the human brain here.

h01-dot-neuroglancer-demo.appspot.com/#!gs://h01-rel…

cc: @stardazed0
4/ As a reminder, the podcast is available on the following platforms:

On Apple Podcast podcasts.apple.com/podcast/id1548…

On Spotify open.spotify.com/show/5vgeprhT4…

On Google Podcasts podcasts.google.com/feed/aHR0cHM6L…

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More from @paraschopra

3 Jan
I read 28 books in 2021.

a 🧵 recapping all of them.
1/ This little book is jam-packed with insights about money.

2/ In fact, the learnings from the book resulted in probably my most popular thread so far.

Read 40 tweets
22 Dec 21
The world record for brain-computer interface for typing is 18 words per minute.

In contrast, eye tracking based typing averages around 20-25 words per minute.

This is a good lesson for why cool technology alone cannot win if there are cheaper, low tech alternatives available.
Source for the BCI typing record: the-scientist.com/news-opinion/b…
Typing demo for eye-tracking based systems.

Read 6 tweets
21 Dec 21
Consumers hate getting sold to, companies love it.

a 🧵
1/ Many failed B2C products might have worked out if consumers had the patience to understand what the product might do for them.
2/ But consumers are impatient and if the value is not delivered immediately and continuously, they stop engaging and abandon the product that could have been valuable later.

invertedpassion.com/marketing-need…
Read 14 tweets
21 Dec 21
Studied history of three different brain implants for medical uses (Neuropace, Second Sight, and Stentrode).

The average time from conception to selling the product is 16 years!

Half of this time is R&D and the other half FDA-required clinical trials.
Even after FDA approval, the use of these devices is legally restricted by FDA to people suffering from extreme cases of diseases.

For example, the company that makes this artificial retina (Second Sight) estimated their approved market to be (just) 1500 people in the US.
With 16 years to launch and target market of 1500 people, no wonder this artificial retina costed $150,000.

Unfortunately, they stopped developing this because it wasn't financially attractive.
Read 7 tweets
13 Dec 21
Notes from the #book "Dreams of a final theory" by Steven Weinberg, who won the Nobel Prize in physics in 1979 for unifying electromagnetism and weak nuclear force.

a 🧵
1/ First, a brief on Steven Weinberg.

What amazed me was that he kept working as a professional scientist until the very end.

His last paper uploaded on Arxiv was in Jan 2021 and he passed away in July 2021 at the age of 88.

Huge respect!

arxiv.org/abs/2101.04241
2/ I came across this book as a recommendation by Nima Arkani-Hamed who said this is the book on physics that he would gift to everyone if he could.

My notes from Nima's interview are here:

Read 27 tweets
30 Nov 21
🎉 Announcing October winners of Gaur and Chopra Escape Velocity grants.

We're awarding 6 people under 25 years of age, a sum of Rs 50,000 each.

Their profiles in this 🧵
1/ 🏫 Apoorva is a material science aspirant and wants to pursue a PhD in it.

She will use this money to pay for applications to institutes.

She has an impressive track record: apoorvapjoshi.com
2/ 🏸 Jaspreet is a state-level badminton player who will use the money to advance her Masters' level education.

Unfortunately, her parents passed away and she depends on her grandparents so this money will really make a difference to them.
Read 9 tweets

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