"Last week, more than 15 million new cases of COVID-19 were reported to @WHO from around the world, by far the most cases reported in a single week. And we know this is an underestimate”, says @DrTedros.
“This huge spike in infections is being driven by the Omicron variant."
@WHO @DrTedros "However, the number of weekly reported deaths has remained stable since October last year, at an average of 48,000 deaths a week”, says @DrTedros.
“While the number of patients being hospitalized is increasing, in most countries, it's not at the level seen in previous waves."
@WHO @DrTedros "This is possibly due to the reduced severity of Omicron as well as widespread immunity from vaccination or previous infection”, says @DrTedros.
BUT: "while Omicron causes less severe disease than Delta, it remains a dangerous virus, particularly for those who are unvaccinated."
@WHO @DrTedros 50,000 people are dying every week, @DrTedros repeats:
"Learning to live with this virus does not mean we can, or should, accept this number of deaths."
@WHO @DrTedros “In Africa, over 85% of people are yet to receive a single dose of vaccine”, says @DrTedros. "We can't end the acute phase of the pandemic unless we close this gap."
@WHO @DrTedros COVAX is making progress on this, says @drtedros:
“In December, COVAX shipped more than double the number of doses it shipped in November”, he says. “In the coming days, we expect COVAX to ship its 1 billionth vaccine dose"
@WHO @DrTedros “We still have a long way to go to reach our target of vaccinating 70% of the population of every country by the middle of this year”, says @DrTedros.
"90 countries have still not reached the 40% target. 36 of those countries have vaccinated less than 10% of their populations"
@WHO @DrTedros "In September last year, WHO established the Technical Advisory Group on COVID19 Vaccine Composition” (TAGCOVAC), says @DrTedros, a group of experts to review the implications of variants on the composition of vaccines.
@WHO @DrTedros “Yesterday, TAGCOVAC emphasized the urgent need for broader access to the vaccines we have, and that further vaccines are needed that have a greater impact on preventing infection and transmission”, says @drtedros.
Until these are available, updated vaccines may be needed.
@WHO @DrTedros TAGCOVAC also:
- said "that a vaccination strategy based on repeated booster doses of the original #COVID19 vaccine composition is unlikely to be sustainable”
- emphasized that "the immediate priority for the world is accelerating access to primary vaccination"
@WHO @DrTedros "The overwhelming majority of people admitted to hospitals around the world are unvaccinated”, says @DrTedros. "While vaccines remain very effective at preventing severe disease and death,
they do not fully prevent transmission."
@WHO @DrTedros Q about countries with lowest vaccination coverage:
Many "have achieved very high coverage for immunization against other diseases and eradicated/eliminated diseases”, says Bruce Aylward.
"They know how to run vaccination at scale."
@WHO @DrTedros “While we did not share vaccines for six months, seven months, eight months, what we did share was a lot of misinformation, a lot of bad practice, a lot of problems”, says Bruce Aylward.
@WHO @DrTedros “This is not the time to give up. This is not the time to give in. This is not the time to declare that this is a welcome virus”, says @DrMikeRyan.
"No virus is welcome that kills people."
@WHO @DrTedros @DrMikeRyan "At the present time, we're not able to prevent all infections, but we can limit the spread and we can reduce the sheer number of cases that are occurring right now”, says @mvankerkhove.
"We can also reduce the severity of COVID-19 with vaccination, with earlier clinical care…"
@WHO @DrTedros @DrMikeRyan @mvankerkhove “We are asking everyone to help us reduce the spread”, says @mvankerkhove.
"Because the sheer volume of cases is putting a burden on health care systems. Because even though Omicron is less severe than delta it still is putting people in hospital... It is still killing people."
@WHO @DrTedros @DrMikeRyan @mvankerkhove The omicron curve is “absolutely staggering”, says Aylward. “In 30 years working on inf diseases we have not seen an epidemic curve like this before."
"In the face of something like that, you want to do everything you can to slow this thing down and take the heat out of it."
@WHO @DrTedros @DrMikeRyan @mvankerkhove "We have a choice here and the choice is to wear a mask, get vaccinated do everything you can to slow this thing down so others don't pay a price”, says Aylward.
@WHO @DrTedros @DrMikeRyan @mvankerkhove Question about vaccine mandates (and Djokovic).
“There are circumstances in which vaccine mandates are supported by @WHO", says @DrMikeRyan. But WHO asks governments to be cautious around this and all other measures should be taken first, he emphasizes.
@WHO @DrTedros @DrMikeRyan @mvankerkhove Ryan:
“The best way to get people vaccinated is to inform them, to educate, to have a dialogue and address people's genuine concerns when it comes to information and knowledge about vaccination especially for them, their families, their children, their parents, and community."

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More from @kakape

6 Jan
"Last week, the highest number of #COVID19 cases were reported so far in the pandemic - and we know for certain that this is an underestimate”, says @DrTedros in WHO presser.
While Omicron appears less severe than delta, that does not make it “mild”, he says.
@DrTedros "Just like previous variants Omicron is hospitalizing people and it's killing people”, says @drtedros.
"In fact, the tsunami of cases is so huge and quick that it is overwhelming health systems around the world. Hospitals are becoming overcrowded and understaffed."
@DrTedros “First-generation vaccines may not stop all infections and transmission, but they remain highly effective in reducing hospitalization and death from this virus”, says @drtedros.
That is why other measures are needed too, he says.
Read 8 tweets
30 Dec 21
One of the complexities in talking about #omicron is that we are constantly talking about the variant’s properties on two levels:
in a naive population and in an immune population (in reality many populations with different levels of immunity)
That matters.
Take transmissibility:
It’s been clear from watching #omicron that it spreads faster than delta.
But from the beginning the question has been: Is that because it can infect people delta can’t? Or is it inherently more transmissible?
If you look at the UK’s risk assessment of #omicron for instance, you can see that that question is still not settled:
"there is no clear epidemiological demonstration of transmissibility as distinct from other contributors to growth advantage”
assets.publishing.service.gov.uk/government/upl…
Read 12 tweets
29 Dec 21
Three things were always needed to beat #SARSCoV2: science, solutions and solidarity, says @DrTedros at @WHO presser.
"Science to both understand the pathogen and find solutions to beating it and solidarity to share and deliver those tools wisely and equitably."
@DrTedros @WHO “While science delivered, politics too often triumphed over solidarity”, says @drtedros.
“Populism, narrow nationalism and hoarding of health tools, including masks, therapeutics, diagnostics and vaccines by a small number of countries undermined equity"
@DrTedros @WHO “Misinformation and disinformation, often spread by a small number of people, have been a constant distraction, undermining science and trust in life saving health tools”, says @drtedros.
Read 10 tweets
28 Dec 21
“I didn’t anticipate the havoc polarized politics would wreak on a pandemic response.”

This is a great look back by @HelenBranswell teasing out some pretty grim lessons from the complete dumpster fire of these last two years

statnews.com/2021/12/28/10-…
“For reasons I may never understand, in January and February of 2020 much of the world seemed not to grasp that the new virus that was spreading so rapidly in China wouldn’t stay in China.”
I feel the exact same way. Hard to imagine I will ever quite understand this…
And remember this in the coming weeks:
“The guiding principle of outbreak response is hope for the best but prepare for the worst. It has felt too often in this pandemic that people are forgetting about the second part of that maxim.”
Read 4 tweets
24 Dec 21
One month ago, I wrote a first thread on #omicron (before it was called that) and I said we needed patience and we would learn a lot more.
So where are we today?
A quick #omicron thread before I sign off for a few days:

WHAT WE HAVE LEARNED:
A lot of the early fears have been borne out.
The virus is spreading in many countries just as it did in SAfrica.
It clearly has a huge growth advantage over Delta.
It is a lot better at infecting vaccinated and recovered individuals than previous variants.
BUT:
As the virus has spread, we have seen some hopeful signs as well.
We have seen fewer hospitalisations so far than in previous waves.
We have seen a faster than expected turnaround in South Africa.
We have early data suggesting the virus *might* be inherently milder.
Read 15 tweets
22 Dec 21
Interesting early data on #omicron severity in this preprint from SAfrica.

Main take-away for me still:
Population with high protection from severe disease but low protection from infection means more infections with mild symptoms.
Inherently milder? 🤷‍♂️

medrxiv.org/content/10.110…
The authors compared SGTF cases with non-SGTF cases during the same time period (1/10 - 30/11).

Remember: SGTF is S gene target failure, the signal in certain PCR tests that is currently used as an (imperfect) proxy for omicron infections.
The authors found that the risk of these likely #omicron cases to end up in hospital was only about one fifth the risk (10-30%) of cases without SGTF (likely not omicron)
But once patients were in hospital, their risk of severe disease was about the same.
Read 9 tweets

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