[Thread] 1. What's happening with SA #Omicron hospital + death data?
Waasila Jassat, @nicd_sa:
"Decoupling" between cases, hospitalisations/deaths = continue.
Black: new #COVID19 cases
Grey: hospitalisations
Red: deaths
Cases higher than Wave 1-3, admissions/deaths = lower
2. #Omicron started in Gauteng + spread 2 other provinces within a week. With previous waves the spread 2 other parts of the country took much longer. So with #Omicron the peaks of provinces' hospitalisations/deaths = much closer to each other.
3. #Omicron hospital admissions in SA peaked at about 60% of the #Delta wave and deaths at about 14-15%
4. Excess deaths: 1. Top graph: excess deaths for under 60 2. Lower graph: excess deaths for 60+ 3. Declines over past 2-3 weeks in excess deaths, but not yet for 60+. We're starting 2 see a plateau for 60+ (rise in cases for 60+ = later in wave, so expected 2 decline later)
5. How sick did #Omicron make people? 1. Data = Lancet preprint study 2. Median length of hospital stay:
- #Omicron: 4 days; #Delta: 6 days 3. Severe disease:
- Omicron: 31.7% of admissions; Delta: 63% 4. Deaths:
- Omicron: 9.7% of admissions, Delta: 26.4%
6. Graphs with the same data as in tweet 5, that show how sick each variant made people. Black = #Omicron data.
The % of admitted patients who required supplemental oxygen during the Omicron wave = less than half than of those who needed oxygen of the #Delta wave
7. Admissions of children: 1. Over 20 years: Lower % of admissions in this group for #Omicron (Omicron = 7.2% of cases; Delta: 12%) 2. Under 20 years: Higher % of admissions in this group for Omicron (Omicron = 8.4% of cases; Delta = 3.8%)
8. Although a larger % of younger people got admitted to hospital during #Omicron compared to other waves, they didn't fall as ill as during the other waves (so milder disease and shorter hospital stays).
9. Who got admitted to hospital with #COVID19 and who died during #Omicron? 1. 82% of admissions = unvaccinated people 2. Under 40 years (lower vaccination rates): 90-100% admissions = unvaccinated 3. 82% of deaths = unvaccinated
(vaccinations = self reported)
10. WHO evidence 4 #Omicron so far: 1. Higher % of asymptomatic infections 2. Omicron affects upper respiratory tract more than lower tract 3. Lower risk for hospitalisation 4. Increased risk of reinfection 5. Vaccine effectiveness @ hospitalisation much better than @ infection
11. Summary: 1. #Omicron cases/admissions = decreasing at slower rate than that it had increased 2. Hospitals in SA = not overwhelmed during Omicron 3. Milder disease and fewer deaths during Omicron wave 4. Most admissions + deaths = unvaccinated
• • •
Missing some Tweet in this thread? You can try to
force a refresh
[Thread] 1. BREAKING: Treasury has awarded @healthza emergency funds of R753 528-mil via section 16 of the Public Finance Management Act to help fill the gap of the #Trump administration's cutting of #HIV and #TB grants.
2. R590 407-mil of the total of R753 528-mil will go to provinces for #HIV service delivery.
R32 121-mil will go to @healthza to support the CCMDD programme (this delivers chronic meds such as #ARin communities so people don't have to line up at clinics)
3. R132-mil of the total of R753 528-mil will go to the SA Medical Research Council to support medical research (lots of US grants were lost, especially from the NIH, although it looks like some of cuts may now be recversed by the NIH. science.org/content/articl…
🧵1. BREAKING: The peer-reviewed results of the study of a 6-monthly jab, #lenacapavir, in which not a single of the 2134 women between 16-25 years who received the jab contracted #HIV, were released at #Aids2024.
2. Women often find it hard to adhere to daily #oralPrEP. In the Purpose 1 trial, 91.5% of women returned on time for their next #lenacapavir jab at 26 weeks and 92.8% at week 52.
3. Only 4 women out of 2134 (0.2%) who received #lenacapavir dropped out of the trial because of injection-site reactions.
[Thread] 12 things to know about the the proportion of pregnant women infected with #HIV from SA’s latest antenatal HIV survey. The survey is conducted by the @nicd_sa.
(Analysis of our 95-95-95 goals in my next thread later in Jan).
1/12
2. What is the antenatal #HIV survey?
1. It measures the % of HIV+ pregnant women between the ages of 15 + 49. 2. Only women using state pregnancy clinics take part. 3. The survey has been conducted each year between 1990-2015, then in 2017, 2019 +2022.
3. How many pregnant women between 15-49’s blood was tested for #HIV? 37 828 out of 40 542 collected samples.
- 37 7171 = Black African women
- 37 541 didn’t live with the dad of their child
- 35,635 of dads were 5 years+ older than moms (this makes them more likely to get HIV)
JUST IN [Thread]:
1.@healthza's Lesley Broomberg:
An extra #COVID19 booster jab for people of 18+ in SA will become available towards the end of JANUARY
- People of 50+ qualify for a 5th dose
- People of 18+ qualify for a 4th dose
2. Lesley Broomberg: Can you mix and match with additional boosters? Yes. You can choose whether you want a #JnJ or #Pfizer booster.
3. Lesley Broomberg:
Will teens of 12-17 qualify for boosters? Not at this stage. Why not? The #VMAC = not recommended booster doses for 12-17, based on an understanding that the protection provided by 2 #Pfizer doses = adequate, as 12-17 = @ low risk of severe #COVID19 illness
[Thread] #JoePhaahla:
- Genomic surveillance Network reported the detection of the new subvariant XBB.1.5 in SA of a sample of a patient tested on 22 Dec
- Details of the patient = not known, it was a random sample taken for testing
- XBB.1.5 = also common in US
2. XBB.1.5 = common in US
#JoePhaahla:
- 97%+ of #COVID19 cases worldwide = still #Omicron
- XBB.1.5 cases = no major change in hospitalisations or deaths
- Immunity of SAs (vax and natural immunity) = still strong, so that is why we haven't seen much change in terms of hospital admissions/deaths
Which APIs will Aspen use?
India's Serum Institute's
2. Why is it NB that an African company makes these jabs?
#Africa imports almost all its jabs. #COVID19 showed us this results in Africa being last in line to get vaccines during pandemics. The grant to Aspen is 1 of the 1st steps to change that.
3. What's the goal?
By 2040, the African Union wants #Africa to make 60% of the jabs the continent uses.
Why?
So that Africa is better equipped 2 respond 2 outbreaks (by developing the ability to make jabs + have technology in place to also make new jabs during pandemics).