THREAD - STATE OF COVID IN UK

Quite long but hopefully comprehensive thread on where we are...

TLDR: cases increasingly hard to interpret, hosp & deaths declining, schools big issue, new (but not more severe) subvariant growing 1/18
Vax - vaccinations have dropped off a cliff in 2022. 80K a day vs almost 1 million before Xmas.

And it's not cos we've finished! Esp NI has only 50% of pop boosted.

We need to keep trying to increase uptake - messaging that pandemic is over and omicron mild doesn't help. 2/18
PCR tests have dropped off massively too since we've stopped requiring confirmatory tests for LFDs. *Reported* use of LFDs is also dropping.

Some is less infection, but not all. Will make both reported cases & positivity rate (based on PCR) hard to interpret. 3/18
NI calcs +ve rate differently now so is on separate plot.

Positivity and cases are now flat for all nations except NI.

Since 31st NI & England reporting reinfections >90 days after 1st, Wales >42 days after 1st and Scotland not yet... 4/18
Can see (approx) impact of adding known reinfections in England here - the increase in reinfections with Omicron is clear -> ~10% of cases each day.

It's great that UKHSA have added them now, but with Omicron it's possible 90 days is too long an interval... 5/18
Reported cases suggests Scotland & Wales back to Nov levels, but ONS infection survey says nowhere near & that scot & wales going up.

Meanwhile, Zoe symptom tracker app says cases back to peak levels. Each measuring diff thing over diff timescale but usually consistent. 6/18
So cases are still *v high* but trend hard to interpret. Hospitalisaitons are going steadily down which is good.

That said, NHS staff absences are still much higher than last 2 yrs so still a lot of pressure in terms of staffing as well as higher occupancy than autumn. 7/18
In terms of death, deaths by day reported went over 500 this week which caused lots of misleading reporting. Need to look at 7-day avgs *and* numbers by date of death (a bit lagged).

Deaths seem to have peaked ~300 a day - still high! but nowhere near 500. 8/18
So what is on horizon? Well, Omicron has 3 main types: BA.1 (main one in UK), BA.1.1 (daughter of BA.1) & BA.2 (sibling of BA.1).

BA.1.1 seems to outcompete BA.1 and BA.2 outcompetes both. 9/18
Denmark has higher vax rates than us & BA.2 now dominant - v high cases (equiv to >600K a day here!).

But while deaths & admissions are rising, they are in line with less severity (given case numbers!). ICU cases are falling still. So BA.2 prob no more severe than BA.1 10/18
In England, BA.1.1 has been taking over from BA.1, but now BA.2 seems to be outcompeting both.

BA.2 most prevalent in N Ireland (which has high case growth now!) & London & SE in England. 11/18
While on variants, ONS released analysis of chance of symptoms (on day of test only - symptoms could be over or still to come).

Both Delta & Omicron more likely to cause symptoms than Alpha *and* 2nd infections just as likely to have symptoms as 1st Delta infections. 12/18
And then... children & schools. Dashboard says cases in kids & parents' generation flat or declining. Zoe app says they are going up.
ONS infection survey shows cases 2x higher in primary than secondary and high.
Next week's ONS will show whether case trend up or down. 13/18
And these high infections have consequences. Admissions in children stay stubbornly (relatively) high with Omicron - and data suggests Omicron is *not* milder for kids.

Plus Long Covid has been going up in kids & school staff. 14/18
ONS also released vaccination updates this week.

Firstly, vaccinations in teens is still much lower than in adults - esp second doses.

Secondly, rates are much lower in schools in more deprived areas. 15/18
For teenagers who had been vaccinated, most common reason was to protect others and then themselves.

So, although JCVI do not consider benefits to others in their decisions on child vax, it's worth noting that teens do consider it.

Also, most parents would vax 5-11 yrs. 16/18
And finally - ventilation! almost third of schools said that good ventilation was hard to implement.

Half said not enough CO2 monitors, and 10% of CO2 monitored rooms had poor readings and no way of improving. 17/18
Accepting that the virus is airborne is vital to learning to adapt to Covid - that means we need to understand mask use & how we make air cleaner.

So please do watch this discussion in Indie SAGE today with @trishgreenhalgh & @adsquires! 18/18
PS thanks to Bob Hawkins as ever for his help with getting some of the data & plots!

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More from @chrischirp

Jan 24
So, we're back - as predicted in mid Dec (!) - in two epidemics - a growing one in children (& flat in their parents' generation) and declining in everyone else.

Unvaxxed children in schools have highest and fastest growing rates - ie 5-9 yr olds. Cases >2x higher than Dec. 1/5
And equally, while hospital admissions fall in adults, they are higher than ever and rising in children.

While most admissions are short and children recovering quickly, they are still sick enough to come to hospital.

We don't know about Omicron & PMS-TS, Long Covid etc 2/5
Most other high income countries are far ahead of us in vaccinating teens and 5-11 year olds.

We know the vaccines are safe and protect against severe illness. SAGE reported that recent teen Covid admissions to ICU were all unvaccinated. 3/5
Read 6 tweets
Jan 18
THREAD: Quick UK Covid update...

I didn't get chance to do thread after Friday @IndependentSage briefing (viewable here: )

so here is a quick update.
TLDR: cases and admissions have likely peaked, but expect schools to prolong the wave... 1/10
Reported cases have peaked and in all nations.

While many things affect case reporting, positivity rates are also falling (good). ONS always lags by a week or two, but hopefully we will see sustained drops in a week or two.

BUT prevalence is still *extraordinarily* high. 2/10
Cases are now falling in all English regions - you can see a clear pre-Xmas change in London likely driven by people cancelling plans to avoid being sick at Xmas.
NE last to peak, but it has.

Again ONS is a bit lagged, but shows London has and other regions flattening 3/10
Read 10 tweets
Jan 12
Short thread on kids, Omicron, hospitalisations:

The US is seeing record hospitalisations among children with Covid.
cbsnews.com/live/video/202…

New York has released a *very preliminary* analysis of admissions since Omicron 1/4
health.ny.gov/press/releases…
First they find that the largest *increase* in Covid admissions by age was in children, particularly under 12s and under 5s. This was both in admissions *for* and admissions *with* - about 60% were directly for Covid.

About half had no pre-existing health conditions. 2/4
They do a very preliminary comparison between Omicron and Delta (unvaccinated patients only) and find that while Omicron seems to be causing fewer hospitalisations in *adults*, the opposite is true in *children*.
Again this is preliminary but needs to be looked into further. 3/4
Read 4 tweets
Jan 9
A virus isn't endemic just cos a govt minister says it is and just cos people want it to be.

The current pattern of waning vax, new immune evasive variants, and minimal public health response seem set to doom us to massive surges once or twice a year. 1\5
If that continues we'll keep picking off the vulnerable, keep stressing a weakening NHS, create more chronic illness & mass disruption through people off sick every time. Lower quality of life for all of us.

Uncertainty in being able to plan months ahead cos of variants 2\5
And when the next pandemic comes, do we just add that disease to our repertoire after a period of mass death?

What when diseases like malaria move north through climate change?

What about rest of the world?

We're moving backwards. 3\5
Read 5 tweets
Jan 7
THREAD on UK Covid situation:

TLDR: not over yet. Good news is high booster coverage in over 50s & no rise in ICU. Bad news is high strain on hospitals, no plan for schools & worsening admissions & long covid for kids.

+ Indie Sage has some suggestions...

1/21
Firstly Omicron - now dominant in Scotland, Wales & England. Probably in NI but no recent data. N Ireland is about week behind other nations.

Omicron dominant in all English regions, London c. 1 week ahead.

Omicron's rise has been very rapid! 2/21
Omicron is v good at infecting vaxxed people - even being boosted only gives you about 40% protection after 10 weeks.

Booster gives *88%* protection against hospital admission - GET IT!

NB booster hosp protection for Delta was close to 100%, Omicron has made things worse. 3/21
Read 23 tweets
Jan 2
I rarely quote tweet but this is not right.

Firstly, it's airborne - that means aerosols are as important as droplets.

That means masks and ventilation are crucial steps and both necessary.

Second, there is excellent evidence on masks in schools: 1/4
Read 6 tweets

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