1/ I think this is a fair question to bring forward given a severe MI can associate with reduced LDL at admission and within days of the event.
But that's also why I like this study design so much -- they exclude known CAD (coronary artery disease) at baseline...
But that's also why I like this study design so much -- they exclude known CAD (coronary artery disease) at baseline...
https://twitter.com/coral_dew/status/1492858095122493445
2/ For a relevant example-- this study makes direct comparisons on symptomatic ("chest pain") patients ultimately diagnosed AMI (acute myocardial infarction, aka heart attack) vs symptomatic yet diagnosed as not having had an AMI... journals.sagepub.com/doi/full/10.41…
3/ "There were significant decreases in TC, LDL and HDL levels in both STEMI and NSTEMI patients as compared to normal subjects; however, patients with chest pain did not show any significant change in these lipids."
4/ In other words, presenting with chest pain but having CAD ruled out shows no statistically significant difference with controls.
(As an aside, the study linked is worth the read in its own right given possible prognostic value of risk severity re presented lipid markers)
(As an aside, the study linked is worth the read in its own right given possible prognostic value of risk severity re presented lipid markers)
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