Here is the MSH3 paper.
Note the supplement doesn’t look at 16S sequence. This is one of the most common sequences on Earth and this 19bp has a 10-11bp match to it. This destroys its E value.
It’s like finding water on Earth. Doesn’t 📌 you down.
Valentine’s Week is the perfect time to zero in on the Mating Type Loci in Psilocybe cubensis.
Psilocybe is believed to have 4 mating types (tetra polar) and they won’t grow near each other if they are not compatible. This is a pheromone affect. So where is this in the genome?
One hint revealed itself as we were mapping p.envy HiC reads to the new p.envy reference genome. While these genomes share a strain name, they are from spores from different providers. Spores should multiple mating types.
Why does Chromosome 1 have 10x more variation?
So we mapped more genomes and looked at SNP density across the chromosomes and Bingo!
This school is a disgrace. @MiddlesexSchool
Why don’t you recognize the Covid recovered?
How does it feel to be discriminatory towards people who recovered from C19 and have better immunity than your cultish obsession over a vaccine that doesn’t stop transmission?
Woke cult.
I once donated my time to present genomics to your students.
Never again will I help your discriminatory school.
Over 150 articles that demonstrate the Covid recovered have better immunity than your experimental liability free vaccine that doesn’t stop transmission.
The Persistence length of dsRNA is an interesting thought.
4.2kb is about 1um in length. 43T of these is 43,730 kilometers.
The Circumference of the Earth is ~40,000km.
A 100ug injection is enough degradation resistant RNA in your body to circle the Earth.
Caveat... The shot is 99+% ssRNA (in theory) which has a shorter persistence length since it folds on itself but for illustrative purposes, dsRNA is shown. The 4.2Kb is the length of the ssRNA in the shot.
The Antartica metagenomic samples that @jbloom_lab nicely covered has some quirks.
NCBI claims its Illumina Data
Fastq files have headers that look like MGISeq data.
So I decided to take a look at their Adaptor sequences as each sequencer has their own unique flow cell primers
TrimGalore indeed confirms these are MGISEQ reads.
This paper has the MGISEQ adaptor sequences- frontiersin.org/articles/10.33…
Why does this matter? The authors posit that this could be a result of the high index hopping problem seen on Illumina platforms.
MGISEQs documented index hopping rate is orders of magnitude lower than Illumina. bmcgenomics.biomedcentral.com/articles/10.11…