#LongCOVID can trigger high level of inflammation and consequent cause damage in the brain and other organs, or blood clotting, leading to a "perpetual and viscous cycle" of chronic symptoms. 2/5 #LongCOVIDConference
There is no single impact either. Examples of patients scans show inflammation, ischemic lesions, haemorrhagic transformation, and microhemorrhages.
“So you can see any pattern of involvement in the brain”- says Dr Paul Edison @ImperialBRC 3/5 #LongCOVIDConference
There may also be a possible mechanism of progressive neurodegeneration in people long past the acute phase as scans show loss of grey matter and other complications - Dr Paul Edison on neurological complications of #LongCOVID 4/5 #LongCOVIDConference
Given that we have the tools through which to study these patients with neurological complications, these must be utilised for a longer-term understanding of their experience and their condition. 5/5 #LongCOVID#LongCOVIDConference
Follow #LongCOVIDConference to join in the conversation and to stay updated on the latest research being discussed at our conference.
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@hugh_montgomery “What's the relationship between asthma and #LongCovid? @ollieosul – “It seems ppl with asthma in the military fared similar to those w/o asthma @Breathe_to_win “we were preparing for a devastating effect on asthma patients, but that wasn’t borne out”
Q: “If you were to get #COVID, would you rest & wait or try to improve your outcome through exercise” @hugh_montgomery
A: @Breathe_to_win “Data into other infections suggests light exercise if able is beneficial. Rest for 48h and then if symptoms allow – light exercise.
Shortness of breath is one of the major symptoms. Traditional pulmonary rehabilitation is difficult to implement on scale. We require a ‘highly individualised approach to help those experiencing #LongCOVID’ says @MMcNarry#LongCOVIDConference 2/6
Respiratory muscle training helps to strengthen the breathing muscles, worked for other types of respiratory conditions. @MMcNarry carried out study, where participants used a small handheld breathing device. This tracked every breath & gave participants instant feedback 3/6
In Brazil, response to chikungunya offers a comparable: "What made chikungunya crippling to the health system is that a small % of people who get it go on to have chronic symptoms which then have a huge impact on people and livelihood." - Prof @Daltmann10 1/4 #LongCOVIDConference
Awareness and knowledge are changing through the pandemic. We’re building better evidence as time has gone.
A #LongCOVID biosignature offers a diagnostic test to help us understand what’s gone wrong and where to go next. 2/4 #LongCOVIDConference
Omicron is significantly different form previous variants – we don’t know how it’ll affect #longCOVID and what the future holds. 3/4 #LondCOVIDConference
‘Long COVID is an uncharted pathophysiology’ We’re still none the wiser in decoding the unknowns. Is long COVID a story of months, years or lifetime?
Prof Danny Altmann @Daltmann10 speaking at the #LongCOVIDConference 1/5
If 10-20% COVID19 infections lead to #LongCOVID. We already face a legacy of 20-240 million long term cases to manage globally 2/5 #LongCOVIDConference
A lot of the research effort at the beginning was purely observational and not interventional. Now we need to manage patients well and offer therapeutics. 3/5 #LongCOVIDConference
In the initial reporting, there was a large focus on death and survival. But "LongCOVID does not paint a black and white picture," says @Dr2NisreenAlwan. The grey area of chronic post-viral illness is missing from the narrative. 2/7 #LongCOVIDConference
Even now, #LongCOVID is unacknowledged by UK policy makers and is missing from health policy discussions, despite 1.3 million people suffering from the condition. (data from ONS survey) 3/7 #LongCOVIDConference