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Tracy Høeg, MD, PhD Profile picture
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Feb 28 • 4 tweets • 2 min read
At #UrgencyOfNormal we are working on a few new slides to help the public understand the risks of covid to kids. This compares infection fatality rate
from influenza (🔵) by year, based on CDC estimates
w/that of COVID-19 2020-2022 (🟠)
TY to Ram Duriseti, MD PhD for this
Link to covid data here: cdc.gov/coronavirus/20…

Influenza data cdc.gov/flu/about/burd…
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More from @TracyBethHoeg

Tracy Høeg, MD, PhD Profile picture
Mar 1
Danish vs NY child vax data:
🇩🇰w/up-to-date vax data (NY data ended 1/30)
In Denmark
Case rates 6-11, 12-15 & 16-19 all slightly *lower* in unvax'ed (🟠) than 2 doses (🔵)
Hospitalizations rates: *unvaccinated* (light blue) 5-11 & 12-15 years have lowest hospitalization rates 1/ Image
Links to the different displays of current @SSI_dk 🇩🇰data
covid19danmark.dk/#gennembrudsin…
experience.arcgis.com/experience/aa4…
2/
When I look at these hospitalization & infection rates in the 6-11 and 12-15 year olds, I see no clear difference in vaccine effectiveness to suggest the lower dose is less effective; I'm just not seeing effectiveness at all but we really need to know previous infection status 3/ ImageImage
Read 7 tweets
Tracy Høeg, MD, PhD Profile picture
Feb 27
Be it 2 or 3 doses of mRNA vax of course @ZDoggMD was right that it doesn't make sense to mandate vax for kids' for entry to a museum
Latest Danish data showing
2 (🔵) & 3(🟢) doses vax no lower case rates than 0 vax (🟠)
& all doses approx same household secondary attack rate 1/
Data on the left from @KT_Baek (who also just left Twitter) using @SSI_dk data & study on the right here (medrxiv.org/content/10.110…). People arguing for mandating child vax I think aren't clear about what they are trying to achieve. It's not going to reliably decrease transmission
People suggesting all kids are more likely to benefit from vaccination than be harmed have yet to produce data that shows this to be the case for healthy kids who have already been infected. In this study >70% of 12-17 had been infected in May of 2021!
academic.oup.com/ofid/article/9…
Read 7 tweets
Tracy Høeg, MD, PhD Profile picture
Feb 19
Many suggest "hybrid immunity" (hx of infection + vax) is superior to immunity from infection alone, but we now have 2 large studies not detecting additional benefit of vax after infection for prevention of hospitalization.
This best was just published 👇:
acpjournals.org/doi/10.7326/M2…
This Israeli study is very large & well done bc of their case-control design which matched vax'ed & controls for age, sex, socioec status status, comorbidities & exposure period. They found 1 dose of vax atfter infection offers no detectable additional benefit vs hospitalization
The second from MMWR is here finding the hospitalization rate among previously infected plus vaccinated was not lower than those who were previously infected but unvaccinated.
Figure on the right from @PeterAttiaMD

cdc.gov/mmwr/volumes/7…
Read 7 tweets
Tracy Høeg, MD, PhD Profile picture
Jan 28
🇩🇰Data from Denmark, still showing 0 correlation of vax or booster w/covid infection
🟠unvaccinated
🔵fully vaccinated
🟢3 doses
The idea vax mandates prevent transmission needs to be dropped, esp considering the study in next tweet
TY @SSI_dk @KT_Baek
covid19danmark.dk/#gennembrudsin…
This study, also from Denmark, found very similar secondary attack rates w/omicron after 0, 2 or 3 doses of vax, meaning once people are infected, the vax does not effectively prevent them from spreading to others in their household

See blue circles

medrxiv.org/content/10.110…
With this in mind, check out this discussion w/@VPrasadMDMPH & @ID_ethics about why mandating COVID-19 vaccination in children now is non-sensical, unethical and may lead to erosion of trust in public health and increase overall vaccine hesitancy
Read 4 tweets
Tracy Høeg, MD, PhD Profile picture
Jan 25
“We need to make sure schools are safe” said @DrPanMD about mandating vax for all school kids in California
For a vax that doesn't prevent transmission & has yet-to-be-fully-defined side effects, requiring it for kids to get an education is non-sensical🧵
latimes.com/california/sto…
1. Vax does not prevent infection
2. Those already infected gain no clear additional protection against severe disease from vaccination
Read 5 tweets
Tracy Høeg, MD, PhD Profile picture
Jan 22
🇩🇰New important Danish data
-HIGHER rates of infection among vaccinated 5-11 yos, even when adjusting for testing rate
-Boosters not associated w/lower infection rates
🟠unvaccinated
🔵2 doses
🟢booster
Data on severe disease & thoughts on mandates 👇
covid19danmark.dk/#gennembrudsin…
Here are COVID ICU (left) & hosp (right) admissions by vax category & age. Boosters have no clear association w/severe disease <age 40-50. This is consistent w/ Israeli data published in NEJM which found no significant correlation w/severe disease <age 40 nejm.org/doi/full/10.10…
Given the above, it's hard to argue college booster mandates are based in science. And, given even small risk of severe adverse events, are unethical. So this explanation 👇 sadly makes more sense than anything based in good public health or compassion
Read 7 tweets

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