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May 7 13 tweets 8 min read
Dr. Scott Commings. Beyone Meat: What alpha-gal syndrome teaches us about the immune response to tick bites.
Dr. @scott_commins says they first began to notice patients complaining of delayed reactions to beef in mid-2000's.
Commings says Initially the only test they had for Alpha-gal was a two step skin test.
Alpha-gal by the numbers. From 2013 to 2018 positive test results went from a few dozen patients to over 30,000. #ticks #alphagalsyndrome #allergies
Management of alpha-gal syndrome includes avoiding mammalian meats, and products that are derived from these products.
Commings says rhere are two types of alpha-gal syndrome & clinical presentations. #AGS
.@scott_commins says, in general Alpha-gal syndrome is managed through avoidance. #AGS
Initially they didn't understand the role ticks had in creating Alpha-gal syndrome. By performing blood tests after known tick bites they now know #AGS is triggered by tick bites.
We have an entire page on our website devoted to Alpha-gal Syndrome - Symptoms, Diagnosis & Treatment lymedisease.org/alpha-gal-synd… via @Lymenews
This is not comprehensive data but it does show a large spread of Alpha-gal syndrome. In the US it appears to come from the Lone star tick (and possibly the I. scapularis & I pacificus). In Japan & other parts of the world other ticks are involved.
Commins currently using Rhapsody to detect surface markers to determine how ticks actually cause alpha-gal allergy and other illnesses
In summary, this is how tick bites lead alpha-gal syndrome @scott_commins
Apologies Dr. @scott_commins autocorrect kept adding a “g” to your last name.

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More from @Lymenews

May 7
Next is Dr. @aucott_john on Lyme disease and infection associated chronic illness. Lessons from COVID Long Haulers and ME/CFS.
Infection associated illness is not new. #LymeDiseaseAwarenessMonth
Dr @aucott_john quickly noticed the symptoms of #LongCOVID were very similar to #LongLyme. Can occur in patients with mild illnesss. Something similar in how these diseases are affecting humans (P.S. Long-haul does not occur post-flu.) #LymeDiseaseAwarenessMonth
Patients with chronic illnesses are often disbelieved. It is difficult as there are no diagnostic tests to prove "Long haul" is real.
Read 16 tweets
May 7
Jeff says they were able to present the @liv_lyme @TicktrackerAPP to the The National Association and County and City Health Officials (NACCHO) and the Centers for Disease Control and Prevention (CDC) during Vector Week. #LymeDiseaseAwarenessMonth
Since it's launch in 2018 @TicktrackerAPP has had over 8,000 submissions. Submissions peak in May-June. American dog tick was number one tick identified. #LymeDiseaseAwarenessMonth
Detail on @TicktrackerAPP submissions. They are working to improve the program to help better identify ticks especially nymphs. #LymeDiseaseAwarenessMonth
Read 5 tweets
May 7
Tickborne Disease Updates from Sue Visser, DrPH, MS Associate Directors for Policy and Extramural Program @CDCgov Division of Vector-borne Diseases Image
Visser pointing out that surveillance is comes from the states. ImageImage
Visser. Pointing out the challenges and opportunities for #LymeDisease surveillance. #LymeDiseaseAwarenessMonth ImageImage
Read 7 tweets
May 7
Dr. Jayakumar Rajadas on the striking similarities & possible therapeutic options for #LongCOVID & #LongLyme #LymeDiseaseAwarenessMonth
Dr. Rajadas, a pharmacologist by training, finding doxycycline is not clearing infection in the lab. However, mitomycin & azlocillin are working well. Prefers fewest number of molecules as treatment option (1 or 2 at most). #LymeDiseaseAwarenessMonth
Rajadas finding TLR2 interaction in both Borrelia and SARS-Cov-2 surface proteins, also elevation of quinolinic acid. #LymeDiseaseAwarenessMonth
Read 9 tweets
May 7
Next is Dr. Saravanan Thangamani @Thangamani_Lab Emergence of ticks and tick-borne diseases in NY.
Deer tick
Lone star tick
Dog tick
Asian longhorned tick
Dr. @Thangamani_Lab reviewing the many pathogens carried by Deer tick, Lone star tick, Dog tick, Gulf coast tick, and the invasive Asian longhorned tick. #LymeDiseaseAwarenessMonth
Dr. @Thangamani_Lab started a citizen science project in 2019 that allows citizens to send in ticks that they are able to use for research. number of ticks and the % pathogens they carry are increasing. #LymeDiseaseAwarenessMonth upstate.edu/whatsup/2021/0…
Read 5 tweets
May 7
Dr. Monica Embers | Persistent Lyme Disease: Supportive Evidence and Potential Solutions. #LymeDiseaseAwarenessMonth
Embers "there are three potential causes of post-treatment #LymeDisease
Inflammatory response
Continuous infection
Autoimmune
The standard treatment for #LymeDisease utilizes a bacteriostatic antibiotic which slows the growth of the bacteria and relies on the immune system to clear the infection.
Read 9 tweets

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