BTI relative risk and absolute excess burden at 6 months for death, particularly increased for clot-related, lung sequelae
Less risk of #LongCovid sequelae with BTI compared with unvaccinated Covid
This graph breaks down the risk of BTI by out-patient or hospitalized/ICU. For the common, non-severe breakthrough infections, the risks are still increased during 6-month follow-up for multiple outcomes
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It took only 10 months from sequencing #SARSCoV2 to validation of mRNA vaccines with 95% efficacy in large, placebo-controlled, randomized clinical trials
The "Delta" (L452R) mutation found in both the BA.2.12.1 and BA.4/BA.5 variants is key to both immune escape and enhanced cell fusion (not present in BA.1 or BA.2). And people with prior Delta infections have better neutralization to these variants biorxiv.org/content/10.110…
Interesting new @NEJM report by same group, @ShanLuLiu1 and team @OhioState,
for Deltacron's (no L452R mutation, recombinant Omicron w/ Delta) substantial immune evasion with no enhanced sensitivity to serum from Delta wave nejm.org/doi/full/10.10…
A big day for life science
The Tabula Sapiens, like a Periodic Table of Human Cells, ~500,000 cells analyzed, 24 tissues / organs @ScienceMagazine
"a broadly useful reference to deeply understand and explore human biology at cellular resolution" science.org/doi/10.1126/sc…
A contemporary assessment of sensors and #AI algorithms for a broad range of use cases including individualized nutrition, pandemic surveillance, disease management and digital therapeutics
You know it's an usual moment in the pandemic when New Zealand leads the world in cases per capita, And is on the descent from its Omicron wave @OurWorldInDatanewsnodes.com/worldmonitor/
New Zealand with a total of 674 deaths for the entire pandemic, chance of dying approximately 1 in 7800, compared with the US, approaching 1 million confirmed deaths, 1 in 333 (24-fold)
A highly Unusual moment (anything but usual).
Sorry for my typo.