American exceptionalism
The United States comprises 4% of the world's population
✓ 16% of the world's Covid confirmed deaths
✓ 40% of world's guns
✓ Only industrialized nation in the world with states making abortion illegal
It took only 10 months from sequencing #SARSCoV2 to validation of mRNA vaccines with 95% efficacy in large, placebo-controlled, randomized clinical trials
The "Delta" (L452R) mutation found in both the BA.2.12.1 and BA.4/BA.5 variants is key to both immune escape and enhanced cell fusion (not present in BA.1 or BA.2). And people with prior Delta infections have better neutralization to these variants biorxiv.org/content/10.110…
Interesting new @NEJM report by same group, @ShanLuLiu1 and team @OhioState,
for Deltacron's (no L452R mutation, recombinant Omicron w/ Delta) substantial immune evasion with no enhanced sensitivity to serum from Delta wave nejm.org/doi/full/10.10…
A big day for life science
The Tabula Sapiens, like a Periodic Table of Human Cells, ~500,000 cells analyzed, 24 tissues / organs @ScienceMagazine
"a broadly useful reference to deeply understand and explore human biology at cellular resolution" science.org/doi/10.1126/sc…
A contemporary assessment of sensors and #AI algorithms for a broad range of use cases including individualized nutrition, pandemic surveillance, disease management and digital therapeutics